Literature DB >> 33457373

Boldo-Induced Hepatotoxicity: A Case of Unexplained Jaundice.

Ana Oliveira Sá1, Teresa Pimentel1, Narciso Oliveira1.   

Abstract

An 87-year-old man was admitted with a 2-week history of asthenia, anorexia and jaundice. Blood tests showed increased serum liver enzymes. The aetiological study was inconclusive. The patient had a favourable clinical evolution during hospitalization with supportive care. His wife revealed that the patient had repeatedly consumed infusions of Peumus boldus (commonly known as boldo) leaves during the previous month. After common causes of hepatobiliary pathology were excluded, boldo-induced hepatotoxicity was considered probable. Cessation of its consumption led to complete clinical and laboratory recovery within a week. LEARNING POINTS: Herbal medicines are commonly used by the public.Peumus boldus leaves consumed as an infusion can be hepatotoxic and may cause otherwise unexplained jaundice or abnormal liver enzyme values, particularly in elderly patients.A detailed clinical history is crucial to establish the consumption of alternative medicines in order to identify possible adverse effects and toxicity. © EFIM 2020.

Entities:  

Keywords:  Peumus boldus; hepatotoxicity; herbal medicines

Year:  2020        PMID: 33457373      PMCID: PMC7806290          DOI: 10.12890/2020_002116

Source DB:  PubMed          Journal:  Eur J Case Rep Intern Med        ISSN: 2284-2594


  2 in total

1.  Caution in the use of boldo in herbal laxatives: a case of hepatotoxicity.

Authors:  Fabio Piscaglia; Simona Leoni; Annamaria Venturi; Franceschini Graziella; Gabriele Donati; Luigi Bolondi
Journal:  Scand J Gastroenterol       Date:  2005-02       Impact factor: 2.423

2.  Hidden Risks of Alternative Medicines: A Case of Boldo-Induced Hepatotoxicity.

Authors:  Ricardo J Ribeiro; Carina Silvestre; Cristina Duarte
Journal:  J Diet Suppl       Date:  2016-08-30
  2 in total

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