Literature DB >> 33452975

Study of Translocation of Stabilized NO Forms through Rat Skin using Electron Paramagnetic Resonance Method.

A A Timoshin1, K B Shumaev2,3, V L Lakomkin2, A A Abramov2, E K Ruuge2,4.   

Abstract

We studied the effect of dinitrosyl-iron complexes with N-acetyl-L-cysteine as a thiol-containing ligand (DNIC-Acc) after transdermal administration to rats. Electron paramagnetic resonance spectroscopy with a lipophilic NO spin trap (a complex of iron and diethyldithiocarbamate ions) showed that DNIC-Acc administration significantly increased the total level of NO in the lung and liver tissues of the animal, which was accompanied by a slight decrease in the mean BP (<10%).

Entities:  

Keywords:  N-acetyl-L-cysteine; dinitrosyl-iron complexes; electron paramagnetic resonance; nitric oxide; spin trap

Year:  2021        PMID： 33452975     DOI： 10.1007/s10517-021-05056-z

Source DB:  PubMed          Journal:  Bull Exp Biol Med        ISSN： 0007-4888            Impact factor:   0.804


  8 in total

1.  Dinitrosyl iron complexes: Formation and antiradical action in heart mitochondria.

Authors:  Konstantin B Shumaev; Arina L Dudylina; Marina V Ivanova; Igor S Pugachenko; Enno K Ruuge
Journal:  Biofactors       Date:  2018-02-22       Impact factor: 6.113

2.  Determination of in vivo nitric oxide levels in animal tissues using a novel spin trapping technology.

Authors:  Anatoly F Vanin; Alexander A Timoshin
Journal:  Methods Mol Biol       Date:  2011

3.  Inhibition of the malate-aspartate shuttle by pre-ischaemic aminooxyacetate loading of the heart induces cardioprotection.

Authors:  Nicolaj Brejnholt Støttrup; Bo Løfgren; Rune Dupont Birkler; Jan Møller Nielsen; Lixing Wang; Christopher Anthony Caldarone; Steen Buus Kristiansen; Hussain Contractor; Mogens Johannsen; Hans Erik Bøtker; Torsten Toftegaard Nielsen
Journal:  Cardiovasc Res       Date:  2010-06-18       Impact factor: 10.787

4.  Polynuclear water-soluble dinitrosyl iron complexes with cysteine or glutathione ligands: electron paramagnetic resonance and optical studies.

Authors:  Anatoly F Vanin; Alexander P Poltorakov; Vasak D Mikoyan; Lyudmila N Kubrina; Dosymzhan S Burbaev
Journal:  Nitric Oxide       Date:  2010-05-27       Impact factor: 4.427

5.  Protein-bound dinitrosyl-iron complexes appearing in blood of rabbit added with a low-molecular dinitrosyl-iron complex: EPR studies.

Authors:  Alexander A Timoshin; Anatoly F Vanin; Tsvetina R Orlova; Natalia A Sanina; Enno K Ruuge; Sergey M Aldoshin; Evgeny I Chazov
Journal:  Nitric Oxide       Date:  2006-10-06       Impact factor: 4.427

6.  Hypotensive Effect and Accumulation of Dinitrosyl Iron Complexes in Blood and Tissues after Intravenous and Subcutaneous Injection.

Authors:  A A Timoshin; V L Lakomkin; A A Abramov; E K Ruuge; A F Vanin
Journal:  Bull Exp Biol Med       Date:  2016-12-02       Impact factor: 0.804

7.  Water-Soluble Dinitrosyl Iron Complex (DNIC): a Nitric Oxide Vehicle Triggering Cancer Cell Death via Apoptosis.

Authors:  Shou-Cheng Wu; Chung-Yen Lu; Yi-Lin Chen; Feng-Chun Lo; Ting-Yin Wang; Yu-Jen Chen; Shyng-Shiou Yuan; Wen-Feng Liaw; Yun-Ming Wang
Journal:  Inorg Chem       Date:  2016-08-30       Impact factor: 5.165

8.  Interaction of reactive oxygen and nitrogen species with albumin- and methemoglobin-bound dinitrosyl-iron complexes.

Authors:  Konstantin B Shumaev; Andrey A Gubkin; Vladimir A Serezhenkov; Irina I Lobysheva; Olga V Kosmachevskaya; Enno K Ruuge; Vadim Z Lankin; Alexey F Topunov; Anatoly F Vanin
Journal:  Nitric Oxide       Date:  2007-10-01       Impact factor: 4.427
  8 in total

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