Madhu Gupta1, Ravi Kanojia2, Adarsh Bansal3, Shivani Aloona3, Monica Rana3, Arun Bansal4, Jayashree Muralidharan4, Kushaljit Singh Sodhi5, Akshay Saxena5, Mini P Singh6, Bhavneet Bharti4, Rajesh Kumar3, Geeta Gathwala7, Poonam Dalal7, Suraj Chawla8, Nayana P Nair9. 1. Department of Community Medicine and School of Public Health, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India. madhugupta21@gmail.com. 2. Department of Pediatric Surgery, Advanced Pediatric Centre, Postgraduate Institute of Medical Education and Research, Chandigarh, India. 3. Department of Community Medicine and School of Public Health, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India. 4. Department of Pediatrics, Advanced Pediatrics Centre, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India. 5. Department of Radiodiagnosis and Imaging, Postgraduate Institute of Medical Education and Research, Chandigarh, India. 6. Department of Virology, Postgraduate Institute of Medical Education and Research, Chandigarh, India. 7. Department of Pediatrics, Postgraduate Institute of Medical Sciences, Rohtak, Haryana, India. 8. Department of Community Medicine, Shaheed Hasan Khan Mewati Medical College, Nalhar, Nuh, Haryana, India. 9. The Wellcome Trust Research Laboratory, Christian Medical College, Vellore, Tamil Nadu, India.
Abstract
OBJECTIVE: To describe epidemiology of intussusception post-introduction of the rotavirus vaccine. METHODS: Hospital-based active surveillance system was set up in three tertiary care hospitals in Chandigarh and Haryana, India, to enroll children <2 y of age admitted with intussusception as per Brighton Collaboration Level-I criteria. The clinical characteristics, treatment modalities, seasonal trends, and outcome of the illness episodes were described. RESULTS: A total of 224 cases were reported. Majority were males (71%) and infants (69.5%). Number of intussusception was more in summer season. Location of intussusception was ileo-colic in 85% of the cases. Nearly 54% cases were treated conservatively and 46% needed surgical intervention. CONCLUSION: Surveillance data provided the epidemiological description of intussusception cases post-introduction of the rotavirus vaccine in northern India. This data could be used to assess the impact of vaccine and safety with a special focus on intussusception.
OBJECTIVE: To describe epidemiology of intussusception post-introduction of the rotavirus vaccine. METHODS: Hospital-based active surveillance system was set up in three tertiary care hospitals in Chandigarh and Haryana, India, to enroll children <2 y of age admitted with intussusception as per Brighton Collaboration Level-I criteria. The clinical characteristics, treatment modalities, seasonal trends, and outcome of the illness episodes were described. RESULTS: A total of 224 cases were reported. Majority were males (71%) and infants (69.5%). Number of intussusception was more in summer season. Location of intussusception was ileo-colic in 85% of the cases. Nearly 54% cases were treated conservatively and 46% needed surgical intervention. CONCLUSION: Surveillance data provided the epidemiological description of intussusception cases post-introduction of the rotavirus vaccine in northern India. This data could be used to assess the impact of vaccine and safety with a special focus on intussusception.
Authors: Irving Charles Boudville; Kong Boo Phua; Seng Hock Quak; Bee Wah Lee; Htay Htay Han; Thomas Verstraeten; Hans Ludwig Bock Journal: Ann Acad Med Singapore Date: 2006-10 Impact factor: 2.473