Literature DB >> 33447606

Nonoperative Antibiotic Treatment of Appendicitis in Adults: A Survey among Clinically Active Surgeons.

Alexander Reinisch1, Martin Reichert2, Andreas Hecker2, Winfried Padberg2, Frank Ulrich1, Juliane Liese2.   

Abstract

BACKGROUND: As a result of well-publicized studies, the nonsurgical antibiotic therapy of uncomplicated acute appendicitis has been propagated since 2006. A final assessment regarding efficiency and long-term results is not possible; however, nonoperative therapy of acute appendicitis is actually being discussed more diversely and receives a lot of attention. It is still unknown how far this therapy has found its way into everyday clinical care.
METHODS: An online questionnaire was sent to 1,400 randomly selected specialists for general/visceral surgery in Germany. Representativeness was achieved by a preselection according to the geographical origin and the care level of the hospitals.
RESULTS: 14% of surgeons stated that they methodically treat appendicitis conservatively. 38.1% do so in exceptional cases, while 48.8% reject this therapy. For methodically use, sonography or computed tomography is demanded beforehand. Nonoperative therapy is performed more often in metropolitan areas and maximum-care/university hospitals. Patients' request for antibiotic therapy is an important factor for conservative treatment. The main argument against this therapy is "medical doubts." 26% of the surgeons would treat their own appendicitis conservatively. There are distinct associations between the application of conservative therapy, satisfaction with it, and expectations about future development. The response rate was 19.9%.
CONCLUSION: The nonoperative antibiotic therapy of appendicitis is part of clinical practice in Germany. There are differences in preconditions as well as in the acceptance of this therapeutic option with a high proportion of general rejection.
Copyright © 2020 by S. Karger AG, Basel.

Entities:  

Keywords:  Antibiotics; Appendicitis; Nonoperative treatment

Year:  2020        PMID: 33447606      PMCID: PMC7768103          DOI: 10.1159/000506058

Source DB:  PubMed          Journal:  Visc Med        ISSN: 2297-4725


  23 in total

Review 1.  Clinical practice. Acute appendicitis--appendectomy or the "antibiotics first" strategy.

Authors:  David R Flum
Journal:  N Engl J Med       Date:  2015-05-14       Impact factor: 91.245

2.  The efficacy of antibiotic treatment versus surgical treatment of uncomplicated acute appendicitis: Systematic review and network meta-analysis of randomized controlled trial.

Authors:  Napaphat Poprom; Pawin Numthavaj; Chumpon Wilasrusmee; Sasivimol Rattanasiri; John Attia; Mark McEvoy; Ammarin Thakkinstian
Journal:  Am J Surg       Date:  2018-10-09       Impact factor: 2.565

3.  A survey of the practice and attitudes of surgeons regarding the treatment of appendicitis.

Authors:  D Dante Yeh; Joseph V Sakran; Rishi Rattan; Ambar Mehta; Gabriel Ruiz; Howard Lieberman; Michelle Mulder; Nicholas Namias; Tanya Zakrison; Gerd Daniel Pust
Journal:  Am J Surg       Date:  2018-09-01       Impact factor: 2.565

4.  Appendectomy versus antibiotic treatment in acute appendicitis. a prospective multicenter randomized controlled trial.

Authors:  Johan Styrud; Staffan Eriksson; Ingemar Nilsson; Gunnar Ahlberg; Staffan Haapaniemi; Gunnar Neovius; Lars Rex; Ibrahim Badume; Lars Granström
Journal:  World J Surg       Date:  2006-06       Impact factor: 3.352

5.  [Uncomplicated appendicitis: is surgery always necessary?].

Authors:  Uwe Glatz
Journal:  Dtsch Med Wochenschr       Date:  2014-08       Impact factor: 0.628

6.  Antibiotic Therapy vs Appendectomy for Treatment of Uncomplicated Acute Appendicitis: The APPAC Randomized Clinical Trial.

Authors:  Paulina Salminen; Hannu Paajanen; Tero Rautio; Pia Nordström; Markku Aarnio; Tuomo Rantanen; Risto Tuominen; Saija Hurme; Johanna Virtanen; Jukka-Pekka Mecklin; Juhani Sand; Airi Jartti; Irina Rinta-Kiikka; Juha M Grönroos
Journal:  JAMA       Date:  2015-06-16       Impact factor: 56.272

7.  Antibiotic Treatment and Appendectomy for Uncomplicated Acute Appendicitis in Adults and Children: A Systematic Review and Meta-analysis.

Authors:  Mauro Podda; Chiara Gerardi; Nicola Cillara; Nicola Fearnhead; Carlos Augusto Gomes; Arianna Birindelli; Andrea Mulliri; Richard Justin Davies; Salomone Di Saverio
Journal:  Ann Surg       Date:  2019-12       Impact factor: 12.969

8.  Comparison of operative and non operative management of acute appendicitis.

Authors:  Ahmet Nuray Turhan; Selin Kapan; Ersen Kütükçü; Hakan Yiğitbaş; Sinan Hatipoğlu; Erşan Aygün
Journal:  Ulus Travma Acil Cerrahi Derg       Date:  2009-09

9.  Antibiotics for appendicitis! Not so fast.

Authors:  Mazhar Khalil; Peter Rhee; Tahereh Orouji Jokar; Narong Kulvatunyou; Terence O'Keeffe; Andrew Tang; Ahmed Hassan; Lynn Gries; Rifat Latifi; Bellal Joseph
Journal:  J Trauma Acute Care Surg       Date:  2016-06       Impact factor: 3.313

10.  Diagnosis and management of acute appendicitis. EAES consensus development conference 2015.

Authors:  Ramon R Gorter; Hasan H Eker; Marguerite A W Gorter-Stam; Gabor S A Abis; Amish Acharya; Marjolein Ankersmit; Stavros A Antoniou; Simone Arolfo; Benjamin Babic; Luigi Boni; Marlieke Bruntink; Dieuwertje A van Dam; Barbara Defoort; Charlotte L Deijen; F Borja DeLacy; Peter Mnyh Go; Annelieke M K Harmsen; Rick S van den Helder; Florin Iordache; Johannes C F Ket; Filip E Muysoms; M Mahir Ozmen; Michail Papoulas; Michael Rhodes; Jennifer Straatman; Mark Tenhagen; Victor Turrado; Andras Vereczkei; Ramon Vilallonga; Jort D Deelder; Jaap Bonjer
Journal:  Surg Endosc       Date:  2016-09-22       Impact factor: 4.584

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  2 in total

1.  Two years later: Is the SARS-CoV-2 pandemic still having an impact on emergency surgery? An international cross-sectional survey among WSES members.

Authors:  Martin Reichert; Massimo Sartelli; Markus A Weigand; Matthias Hecker; Philip U Oppelt; Julia Noll; Ingolf H Askevold; Juliane Liese; Winfried Padberg; Federico Coccolini; Fausto Catena; Andreas Hecker
Journal:  World J Emerg Surg       Date:  2022-06-16       Impact factor: 8.165

Review 2.  Acute appendicitis-advances and controversies.

Authors:  Thomas Zheng Jie Teng; Xuan Rong Thong; Kai Yuan Lau; Sunder Balasubramaniam; Vishal G Shelat
Journal:  World J Gastrointest Surg       Date:  2021-11-27
  2 in total

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