Literature DB >> 33446890

Predicting adult neuroscience intensive care unit admission from emergency department triage using a retrospective, tabular-free text machine learning approach.

Eyal Klang1, Benjamin R Kummer2,3, Neha S Dangayach4,5, Amy Zhong6, M Arash Kia1, Prem Timsina1, Ian Cossentino6, Anthony B Costa5, Matthew A Levin1,7, Eric K Oermann5.   

Abstract

Early admission to the neurosciences intensive care unit (NSICU) is associated with improved patient outcomes. Natural language processing offers new possibilities for mining free text in electronic health record data. We sought to develop a machine learning model using both tabular and free text data to identify patients requiring NSICU admission shortly after arrival to the emergency department (ED). We conducted a single-center, retrospective cohort study of adult patients at the Mount Sinai Hospital, an academic medical center in New York City. All patients presenting to our institutional ED between January 2014 and December 2018 were included. Structured (tabular) demographic, clinical, bed movement record data, and free text data from triage notes were extracted from our institutional data warehouse. A machine learning model was trained to predict likelihood of NSICU admission at 30 min from arrival to the ED. We identified 412,858 patients presenting to the ED over the study period, of whom 1900 (0.5%) were admitted to the NSICU. The daily median number of ED presentations was 231 (IQR 200-256) and the median time from ED presentation to the decision for NSICU admission was 169 min (IQR 80-324). A model trained only with text data had an area under the receiver-operating curve (AUC) of 0.90 (95% confidence interval (CI) 0.87-0.91). A structured data-only model had an AUC of 0.92 (95% CI 0.91-0.94). A combined model trained on structured and text data had an AUC of 0.93 (95% CI 0.92-0.95). At a false positive rate of 1:100 (99% specificity), the combined model was 58% sensitive for identifying NSICU admission. A machine learning model using structured and free text data can predict NSICU admission soon after ED arrival. This may potentially improve ED and NSICU resource allocation. Further studies should validate our findings.

Entities:  

Year:  2021        PMID: 33446890      PMCID: PMC7809037          DOI: 10.1038/s41598-021-80985-3

Source DB:  PubMed          Journal:  Sci Rep        ISSN: 2045-2322            Impact factor:   4.379


  43 in total

1.  The mutual information: detecting and evaluating dependencies between variables.

Authors:  R Steuer; J Kurths; C O Daub; J Weise; J Selbig
Journal:  Bioinformatics       Date:  2002       Impact factor: 6.937

2.  Overcrowding in emergency department: an international issue.

Authors:  Salvatore Di Somma; Lorenzo Paladino; Louella Vaughan; Irene Lalle; Laura Magrini; Massimo Magnanti
Journal:  Intern Emerg Med       Date:  2014-12-02       Impact factor: 3.397

3.  Prediction of emergency department patient disposition based on natural language processing of triage notes.

Authors:  Nicholas W Sterling; Rachel E Patzer; Mengyu Di; Justin D Schrager
Journal:  Int J Med Inform       Date:  2019-06-13       Impact factor: 4.046

4.  Predictive analytics and machine learning in stroke and neurovascular medicine.

Authors:  Hamidreza Saber; Melek Somai; Gary B Rajah; Fabien Scalzo; David S Liebeskind
Journal:  Neurol Res       Date:  2019-04-30       Impact factor: 2.448

5.  Progressive prediction of hospitalisation in the emergency department: uncovering hidden patterns to improve patient flow.

Authors:  Yuval Barak-Corren; Shlomo Hanan Israelit; Ben Y Reis
Journal:  Emerg Med J       Date:  2017-02-10       Impact factor: 2.740

Review 6.  Outcome in neurocritical care: advances in monitoring and treatment and effect of a specialized neurocritical care team.

Authors:  Jose I Suarez
Journal:  Crit Care Med       Date:  2006-09       Impact factor: 7.598

7.  Current state of trauma care in China, tools to predict death and ICU admission after arrival to hospital.

Authors:  Guilan Kong; Xiaofeng Yin; Tianbing Wang; Richard Body; Yu-Wang Chen; Jing Wang; Liying Cao; Shouling Wu; Jingli Gao; Guosheng Wang; Yonghua Hu; Baoguo Jiang
Journal:  Injury       Date:  2015-06-09       Impact factor: 2.586

8.  Assessment of Deep Natural Language Processing in Ascertaining Oncologic Outcomes From Radiology Reports.

Authors:  Kenneth L Kehl; Haitham Elmarakeby; Mizuki Nishino; Eliezer M Van Allen; Eva M Lepisto; Michael J Hassett; Bruce E Johnson; Deborah Schrag
Journal:  JAMA Oncol       Date:  2019-10-01       Impact factor: 31.777

9.  Machine Learning-Based Prediction of Korean Triage and Acuity Scale Level in Emergency Department Patients.

Authors:  Sae Won Choi; Taehoon Ko; Ki Jeong Hong; Kyung Hwan Kim
Journal:  Healthc Inform Res       Date:  2019-10-31

10.  Prediction of early unplanned intensive care unit readmission in a UK tertiary care hospital: a cross-sectional machine learning approach.

Authors:  Thomas Desautels; Ritankar Das; Jacob Calvert; Monica Trivedi; Charlotte Summers; David J Wales; Ari Ercole
Journal:  BMJ Open       Date:  2017-09-15       Impact factor: 2.692

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  5 in total

Review 1.  Machine Learning and Precision Medicine in Emergency Medicine: The Basics.

Authors:  Sangil Lee; Samuel H Lam; Thiago Augusto Hernandes Rocha; Ross J Fleischman; Catherine A Staton; Richard Taylor; Alexander T Limkakeng
Journal:  Cureus       Date:  2021-09-01

2.  Machine learning for prediction of intra-abdominal abscesses in patients with Crohn's disease visiting the emergency department.

Authors:  Asaf Levartovsky; Yiftach Barash; Shomron Ben-Horin; Bella Ungar; Shelly Soffer; Marianne M Amitai; Eyal Klang; Uri Kopylov
Journal:  Therap Adv Gastroenterol       Date:  2021-10-22       Impact factor: 4.409

Review 3.  Artificial intelligence and machine learning in emergency medicine: a narrative review.

Authors:  Brianna Mueller; Takahiro Kinoshita; Alexander Peebles; Mark A Graber; Sangil Lee
Journal:  Acute Med Surg       Date:  2022-03-01

4.  Machine learning to predict in-hospital mortality among patients with severe obesity: Proof of concept study.

Authors:  Shelly Soffer; Eyal Zimlichman; Matthew A Levin; Alexis M Zebrowski; Benjamin S Glicksberg; Robert Freeman; David L Reich; Eyal Klang
Journal:  Obes Sci Pract       Date:  2022-03-24

5.  Natural language processing in clinical neuroscience and psychiatry: A review.

Authors:  Claudio Crema; Giuseppe Attardi; Daniele Sartiano; Alberto Redolfi
Journal:  Front Psychiatry       Date:  2022-09-14       Impact factor: 5.435

  5 in total

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