Literature DB >> 33446324

Immune Escape in Prostate Cancer: Known and Predicted Mechanisms and Targets.

Boris A Reva1, Tatiana Omelchenko2, Sujit S Nair3, Ashutosh K Tewari3.   

Abstract

Complex immune evasion mechanisms and lack of biomarkers predicting responsiveness to immune checkpoint blockade therapies compromise immunotherapy's therapeutic efficacy for patients with prostate cancer. The authors review established and nominated immune evasion mechanisms in prostate cancer and discuss how the precise treatment strategies can be developed to improve efficacy of immunotherapy.
Copyright © 2020 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  IFN-γ signaling; Immune evasion; Immunotherapy; Prostate cancer

Year:  2020        PMID： 33446324     DOI： 10.1016/j.ucl.2020.10.004

Source DB:  PubMed          Journal:  Urol Clin North Am        ISSN： 0094-0143            Impact factor:   2.241


  2 in total

1.  Reprogrammed Schwann Cells Organize into Dynamic Tracks that Promote Pancreatic Cancer Invasion.

Authors:  Sylvie Deborde; Laxmi Gusain; Ann Powers; Andrea Marcadis; Yasong Yu; Chun-Hao Chen; Anna Frants; Elizabeth Kao; Laura H Tang; Efsevia Vakiani; Masataka Amisaki; Vinod P Balachandran; Annalisa Calo; Tatiana Omelchenko; Kristjan R Jessen; Boris Reva; Richard J Wong
Journal:  Cancer Discov       Date:  2022-10-05       Impact factor: 38.272

2.  LMX1B Activated Circular RNA GFRA1 Modulates the Tumorigenic Properties and Immune Escape of Prostate Cancer.

Authors:  Min Meng; Yi-Chen Wu
Journal:  J Immunol Res       Date:  2022-07-04       Impact factor: 4.493
  2 in total

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