Literature DB >> 3344615

Partial degeneration of autonomic nerves of the heart of methotrexate-treated guinea pigs.

M A Qayyum1, J A Fatani, M G el-Badawi.   

Abstract

In the present investigation partial degeneration of adrenergic and cholinergic nerves of the heart of guinea pigs following methotrexate treatment has been reported. No appreciable change was observed in the autonomic nerve fibres after 3 days of treatment. However, after prolonged treatment some nerve fibres showed signs of degeneration and a few adrenergic and cholinergic nerve fibres had disappeared.

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Year:  1988        PMID: 3344615     DOI: 10.1159/000146485

Source DB:  PubMed          Journal:  Acta Anat (Basel)        ISSN: 0001-5180


  1 in total

1.  In vitro inhibition of human erythrocyte acetylcholinesterase (EC3.1.1.7) by an antineoplastic drug methotrexate.

Authors:  M A Kamal; F H Nasim; A A al-Jafari
Journal:  Mol Cell Biochem       Date:  1996-06-07       Impact factor: 3.396

  1 in total

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