Ju Hee Kim1,2, Jung Eun Lee2, So Min Shim2, Eun Kyo Ha3, Dong Keon Yon1, Ok Hyang Kim1, Ji Hyeon Baek1, Hyun Yong Koh4, Kyu Young Chae1, Seung Won Lee2, Man Yong Han1. 1. Department of Pediatrics, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, Korea. 2. Department of Data Science, Sejong University College of Software Convergence, Seoul, Korea. 3. Department of Pediatrics, Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea. 4. F.M. Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Abstract
Background: An adequate large-scale pediatric cohort based on nationwide administrative data is lacking in Korea. Purpose: This study established the National Investigation of Birth Cohort in Korea study 2008 (NICKs-2008) based on data from a nationwide population-based health screening program and data on healthcare utilization for children. Methods: The NICKs-2008 study consisted of the Korean National Health Insurance System (NHIS) and the National Health Screening Program for Infants and Children (NHSPIC) databases comprising children born in 2008 (n = 469,248) and 2009 (n = 448,459) in the Republic of Korea. The NHIS database contains data on age, sex, residential area, income, healthcare utilization (International Classification of Diseases-10 codes, procedure codes, and drug classification codes), and healthcare providers. The NHSPIC consists of seven screening rounds. These screening sessions comprised physical examination, developmental screening (rounds 2-7), a general health questionnaire, and age-specific anticipatory guidance. Results: During the 10-year follow-up, 2,718 children (0.3%) died, including more boys than girls (hazard ratio = 1.145, p < 0.001). A total of 848,048 children participated in at least one of the seven rounds of the NHSPIC, while 96,046 participated in all seven screening programs. A total of 823 infants (0.1%) weighed less than 1000 g, 3177 (0.4%) weighed 1000-1499 g, 37,166 (4.4%) weighed 1500-2499 g, 773,081 (91.4%) weighed 2500-4000 g, and 32,016 (5.1%) weighed over 4000 g. There were 23,404 (5.5%) premature babies in 2008 compared to 23,368 (5.6%) in 2009. The developmental screening test indicated appropriate development in 95-98% of children, follow-up requirements for 1-4% of children, and recommendations for further evaluation for 1% of children. Conclusion: The NICKs-2008, which integrates data from the NHIS and NHSPIC databases, can be used to analyze disease onset prior to hospitalization based on information such as lifestyle, eating habits, and risk factors.
Background: An adequate large-scale pediatric cohort based on nationwide administrative data is lacking in Korea. Purpose: This study established the National Investigation of Birth Cohort in Korea study 2008 (NICKs-2008) based on data from a nationwide population-based health screening program and data on healthcare utilization for children. Methods: The NICKs-2008 study consisted of the Korean National Health Insurance System (NHIS) and the National Health Screening Program for Infants and Children (NHSPIC) databases comprising children born in 2008 (n = 469,248) and 2009 (n = 448,459) in the Republic of Korea. The NHIS database contains data on age, sex, residential area, income, healthcare utilization (International Classification of Diseases-10 codes, procedure codes, and drug classification codes), and healthcare providers. The NHSPIC consists of seven screening rounds. These screening sessions comprised physical examination, developmental screening (rounds 2-7), a general health questionnaire, and age-specific anticipatory guidance. Results: During the 10-year follow-up, 2,718 children (0.3%) died, including more boys than girls (hazard ratio = 1.145, p < 0.001). A total of 848,048 children participated in at least one of the seven rounds of the NHSPIC, while 96,046 participated in all seven screening programs. A total of 823 infants (0.1%) weighed less than 1000 g, 3177 (0.4%) weighed 1000-1499 g, 37,166 (4.4%) weighed 1500-2499 g, 773,081 (91.4%) weighed 2500-4000 g, and 32,016 (5.1%) weighed over 4000 g. There were 23,404 (5.5%) premature babies in 2008 compared to 23,368 (5.6%) in 2009. The developmental screening test indicated appropriate development in 95-98% of children, follow-up requirements for 1-4% of children, and recommendations for further evaluation for 1% of children. Conclusion: The NICKs-2008, which integrates data from the NHIS and NHSPIC databases, can be used to analyze disease onset prior to hospitalization based on information such as lifestyle, eating habits, and risk factors.
Entities:
Keywords:
Children; Cohort profile; Health screening; Infant; National cohort
Authors: Won Seok Lee; Kyung Suk Lee; Eun Kyo Ha; Ju Hee Kim; So Min Shim; Seung Won Lee; Man Yong Han Journal: Sci Rep Date: 2022-06-17 Impact factor: 4.996
Authors: Ji Hee Kwak; Eun Kyo Ha; Ju Hee Kim; Hye Ryung Cha; Seung Won Lee; Man Yong Han Journal: J Am Heart Assoc Date: 2022-06-14 Impact factor: 6.106