| Literature DB >> 3344569 |
S A Stefanski1, M R Elwell, K Mitsumori, K Yoshitomi, K Dittrich, H D Giles.
Abstract
Tissue sections and records of 56 rats with chordoma, identified in the National Toxicology Program's (NTP) data base of approximately 115,000 rats, were examined to determine morphological characteristics, incidence, and aspects of biological behavior. Chordomas occurred in aged rats, originated predominantly in lumbosacral vertebrae, were highly malignant, occurred three times more often in male versus female rats, and commonly produced bilateral posterior paresis, paralysis, and/or distention of the colon and rectum.Entities:
Mesh:
Year: 1988 PMID: 3344569 DOI: 10.1177/030098588802500106
Source DB: PubMed Journal: Vet Pathol ISSN: 0300-9858 Impact factor: 2.221