Qi Chen1, Yueyun Sang2, Lifang Ren3, Jinping Wu4, Yajun Chen5, Menglei Zheng6, Guolin Bian7, Hanying Sun3,8. 1. Department of Chronic Disease and Mental Health, YinZhou Center for Disease Control and Prevention, Ningbo, China. 47229942@qq.com. 2. Ningbo Mental Health Center, Ningbo Kangning Hospital, Ningbo, China. sangyueyun@sina.cn. 3. Department of Chronic Disease and Mental Health, YinZhou Center for Disease Control and Prevention, Ningbo, China. 4. Department of Community Health, Hengxi Community Health Center, Ningbo, China. 5. Department of Community Health, Maoshan Community Health Center, Ningbo, China. 6. Department of Community Health, Shounan Community Health Center, Ningbo, China. 7. Ningbo Mental Health Center, Ningbo Kangning Hospital, Ningbo, China. 8. LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
Abstract
BACKGROUND: The traditional general practitioner-based model (community-based rehabilitation [CBR]) for Chinese schizophrenia patients lacks sufficient content, usefulness, and theoretical basis for rehabilitation. Based on previous research, we postulate that Metacognitive Training (MCT) is effective in the community for schizophrenic patients. METHOD: A randomized controlled, assessor-blinded trial was conducted. A total of 124 schizophrenia patients were recruited from Ningbo China and were randomly assigned to an intervention or a control group. A general practitioner (GP) training plan was carried out before intervention. Intervention and control groups received two CBR follow-ups once a month, while the intervention group, received an additional eight once-a-in-week session of MCT. The Positive and Negative Syndrome Scale (PANSS), and the Psychotic Symptom Rating Scales (PSYRATS) were the primary outcome instruments, while the Quality of Life Scale (SQLS) was the secondary outcome instrument. RESULTS: In the post-treatment between-groups assessment, the patients in the intervention group showed significantly more reductions on PSYRATS delusions, PSYRATS total, PANSS P6, PANSS core delusions, PANSS positive, PANSS negative, PANSS general and PANSS total, and a significant improvement in SQLS psychosocial aspect. CONCLUSIONS: The study provides preliminary evidence for the usefulness of MCT as a complementary measure for community-based rehabilitation of schizophrenia patients. TRIAL REGISTRATION: ISRCTN, ISRCTN17333276 . Registered 09 August 2020 - Retrospectively registered.
RCT Entities:
BACKGROUND: The traditional general practitioner-based model (community-based rehabilitation [CBR]) for Chinese schizophreniapatients lacks sufficient content, usefulness, and theoretical basis for rehabilitation. Based on previous research, we postulate that Metacognitive Training (MCT) is effective in the community for schizophrenicpatients. METHOD: A randomized controlled, assessor-blinded trial was conducted. A total of 124 schizophreniapatients were recruited from Ningbo China and were randomly assigned to an intervention or a control group. A general practitioner (GP) training plan was carried out before intervention. Intervention and control groups received two CBR follow-ups once a month, while the intervention group, received an additional eight once-a-in-week session of MCT. The Positive and Negative Syndrome Scale (PANSS), and the Psychotic Symptom Rating Scales (PSYRATS) were the primary outcome instruments, while the Quality of Life Scale (SQLS) was the secondary outcome instrument. RESULTS: In the post-treatment between-groups assessment, the patients in the intervention group showed significantly more reductions on PSYRATS delusions, PSYRATS total, PANSS P6, PANSS core delusions, PANSS positive, PANSS negative, PANSS general and PANSS total, and a significant improvement in SQLS psychosocial aspect. CONCLUSIONS: The study provides preliminary evidence for the usefulness of MCT as a complementary measure for community-based rehabilitation of schizophreniapatients. TRIAL REGISTRATION: ISRCTN, ISRCTN17333276 . Registered 09 August 2020 - Retrospectively registered.
Entities:
Keywords:
Community rehabilitation; General practitioner; Metacognition; Schizophrenia
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