Literature DB >> 33438774

Immune subversion by HIV: part B.

Christophe Vanpouille1, Leonid Margolis1.   

Abstract

While HIV-1 infects T but not B cells, it nevertheless impairs the function of B cells and thereby contribute to the failure to produce neutralizing antibodies. In this issue, Kaw et al describe the mechanisms leading to this failure and report a key role for the HIV-1 protein NEF in preventing B-cell maturation into antibody-producing plasma cells.
© 2020 The Authors. This article is a U.S. Government work and is in the public domain in the USA.

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Year:  2020        PMID： 33438774      PMCID： PMC7737603          DOI： 10.15252/embj.2020107167

Source DB:  PubMed          Journal:  EMBO J        ISSN： 0261-4189            Impact factor:   14.012


  12 in total

1.  HIV-1 Nef increases T cell activation in a stimulus-dependent manner.

Authors:  J A Schrager; J W Marsh
Journal:  Proc Natl Acad Sci U S A       Date:  1999-07-06       Impact factor: 11.205

2.  Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection.

Authors:  Gilad Doitsh; Nicole L K Galloway; Xin Geng; Zhiyuan Yang; Kathryn M Monroe; Orlando Zepeda; Peter W Hunt; Hiroyu Hatano; Stefanie Sowinski; Isa Muñoz-Arias; Warner C Greene
Journal:  Nature       Date:  2014-01-23       Impact factor: 49.962

Review 3.  Structure, function, and inhibitor targeting of HIV-1 Nef-effector kinase complexes.

Authors:  Ryan P Staudt; John J Alvarado; Lori A Emert-Sedlak; Haibin Shi; Sherry T Shu; Thomas E Wales; John R Engen; Thomas E Smithgall
Journal:  J Biol Chem       Date:  2020-08-29       Impact factor: 5.157

Review 4.  B-cell responses to HIV infection.

Authors:  Susan Moir; Anthony S Fauci
Journal:  Immunol Rev       Date:  2017-01       Impact factor: 12.988

5.  HIV F/3' orf encodes a phosphorylated GTP-binding protein resembling an oncogene product.

Authors:  B Guy; M P Kieny; Y Riviere; C Le Peuch; K Dott; M Girard; L Montagnier; J P Lecocq
Journal:  Nature       Date:  1987 Nov 19-25       Impact factor: 49.962

6.  Adipocyte extracellular vesicles carry enzymes and fatty acids that stimulate mitochondrial metabolism and remodeling in tumor cells.

Authors:  Emily Clement; Ikrame Lazar; Camille Attané; Lorry Carrié; Stéphanie Dauvillier; Manuelle Ducoux-Petit; David Esteve; Thomas Menneteau; Mohamed Moutahir; Sophie Le Gonidec; Stéphane Dalle; Philippe Valet; Odile Burlet-Schiltz; Catherine Muller; Laurence Nieto
Journal:  EMBO J       Date:  2020-01-10       Impact factor: 11.598

Review 7.  B cells in HIV infection and disease.

Authors:  Susan Moir; Anthony S Fauci
Journal:  Nat Rev Immunol       Date:  2009-04       Impact factor: 53.106

8.  Endocytosis of major histocompatibility complex class I molecules is induced by the HIV-1 Nef protein.

Authors:  O Schwartz; V Maréchal; S Le Gall; F Lemonnier; J M Heard
Journal:  Nat Med       Date:  1996-03       Impact factor: 53.440

9.  Human immunodeficiency virus impairs reverse cholesterol transport from macrophages.

Authors:  Zahedi Mujawar; Honor Rose; Matthew P Morrow; Tatiana Pushkarsky; Larisa Dubrovsky; Nigora Mukhamedova; Ying Fu; Anthony Dart; Jan M Orenstein; Yuri V Bobryshev; Michael Bukrinsky; Dmitri Sviridov
Journal:  PLoS Biol       Date:  2006-10       Impact factor: 8.029

10.  HIV-1 infection of CD4 T cells impairs antigen-specific B cell function.

Authors:  Sheetal Kaw; Swetha Ananth; Nikolaos Tsopoulidis; Katharina Morath; Bahar M Coban; Ralph Hohenberger; Olcay C Bulut; Florian Klein; Bettina Stolp; Oliver T Fackler
Journal:  EMBO J       Date:  2020-11-04       Impact factor: 14.012
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