Literature DB >> 33438346

Evaluation of adding platelet-rich plasma to combined medical therapy in androgenetic alopecia.

Wafaa Mohammad Ramadan1, Arwa Mohammad Hassan1, Mayada A Ismail2, Yasmina Ahmed El Attar1.   

Abstract

BACKGROUND: Androgenetic alopecia (AGA) is a common hair loss disorder.
OBJECTIVES: To evaluate the therapeutic effects of platelet-rich plasma (PRP) in androgenetic alopecia.
METHODS: This study was done on 126 AGA patients, 42 patients survived as control group who received medical treatment, only other 84 patients were subdivided into two groups, and they received PRP sessions as co-adjuvant therapy using different methods administration. Patients were evaluated clinically, by dermoscopy and by digital dermoscopy to measure hair density and diameters before and after treatment.
RESULTS: PRP-treated patients showed statistically significant increase in hair density and diameter measurements than control group. These results increased by using microneedling as a method of PRP administration.
CONCLUSION: In AGA, the addition of "PRP with microneedling" to the combined medical treatment increases its efficacy and shortens the time needed for optimum improvement. STUDY
DESIGN: Single-blinded randomized controlled study.
© 2021 Wiley Periodicals LLC.

Entities:  

Keywords:  androgenetic alopecia; dermoscopy; microneedling; minoxidil; platelet-rich plasma

Mesh:

Year:  2021        PMID: 33438346     DOI: 10.1111/jocd.13935

Source DB:  PubMed          Journal:  J Cosmet Dermatol        ISSN: 1473-2130            Impact factor:   2.696


  3 in total

Review 1.  A Comprehensive Review of Microneedling as a Potential Treatment Option for Androgenetic Alopecia.

Authors:  Lingling Jia; Jiachao Xiong; Rong Guo; Yufei Li; Hua Jiang
Journal:  Aesthetic Plast Surg       Date:  2022-08-05       Impact factor: 2.708

Review 2.  Microneedling and Its Use in Hair Loss Disorders: A Systematic Review.

Authors:  Robert S English; Sophia Ruiz; Pedro DoAmaral
Journal:  Dermatol Ther (Heidelb)       Date:  2021-12-01

Review 3.  Treatment of Androgenetic Alopecia Using PRP to Target Dysregulated Mechanisms and Pathways.

Authors:  Rama Abdin; Yusheng Zhang; Joaquin J Jimenez
Journal:  Front Med (Lausanne)       Date:  2022-03-16
  3 in total

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