Literature DB >> 33435952

Gaining insight into the views of outpatients with Huntington's disease regarding their future and the way they deal with their poor prognosis: a qualitative study.

Marina R Ekkel1, Marja F I A Depla2, Els M L Verschuur3, Ruth B Veenhuizen2,4, Cees M P M Hertogh2, Bregje D Onwuteaka-Philipsen5.   

Abstract

BACKGROUND: Huntington's disease (HD) has a poor prognosis. Decision-making capacity and communication ability may become lost as the disease progresses. Therefore, HD patients are encouraged to engage in advance care planning (ACP). To improve ACP for HD patients, there is a need to better understand how these patients face their poor prognosis. AIM: To gain insight into the views of HD patients who receive outpatient care regarding their future and the way they deal with the poor prognosis of their disease.
METHODS: A qualitative study using semi-structured interviews with 12 patients with HD (7 outpatient clinic, 3 day care, 2 assisted living facility). Audio-recorded interviews were transcribed verbatim. Through reading and re-reading interviews, writing memos and discussions in the research team, strategies were identified.
RESULTS: Three strategies emerged for facing a future with HD. Participants saw the future: 1) as a period that you have to prepare for; 2) as a period that you would rather not think about; 3) as a period that you do not have to worry about yet. Participants could adopt more than one strategy at a time. Even though participants realized that they would deteriorate and would need more care in the future, they tried to keep this knowledge 'at a distance', with the motivation of keeping daily life as manageable as possible.
CONCLUSIONS: Official ACP guidelines recommend discussing goals and preferences for future treatment and care, but patients tend to want to live in the present. Further research is needed to elucidate the best approach to deal with this discrepancy.

Entities:  

Keywords:  Advance care planning; Huntington’s disease; Neurodegenerative disease; Patients’ perspectives; Qualitative research

Year:  2021        PMID: 33435952      PMCID: PMC7802313          DOI: 10.1186/s12904-020-00706-x

Source DB:  PubMed          Journal:  BMC Palliat Care        ISSN: 1472-684X            Impact factor:   3.234


  25 in total

Review 1.  The effects of advance care planning on end-of-life care: a systematic review.

Authors:  Arianne Brinkman-Stoppelenburg; Judith A C Rietjens; Agnes van der Heide
Journal:  Palliat Med       Date:  2014-03-20       Impact factor: 4.762

Review 2.  The effects of cognitive behavioral and mindfulness-based therapies on psychological distress in patients with multiple sclerosis, Parkinson's disease and Huntington's disease: Two meta-analyses.

Authors:  Ires Ghielen; Sonja Rutten; Rosa E Boeschoten; Marieke Houniet-de Gier; Erwin E H van Wegen; Odile A van den Heuvel; Pim Cuijpers
Journal:  J Psychosom Res       Date:  2019-05-13       Impact factor: 3.006

Review 3.  Definition and recommendations for advance care planning: an international consensus supported by the European Association for Palliative Care.

Authors:  Judith A C Rietjens; Rebecca L Sudore; Michael Connolly; Johannes J van Delden; Margaret A Drickamer; Mirjam Droger; Agnes van der Heide; Daren K Heyland; Dirk Houttekier; Daisy J A Janssen; Luciano Orsi; Sheila Payne; Jane Seymour; Ralf J Jox; Ida J Korfage
Journal:  Lancet Oncol       Date:  2017-09       Impact factor: 41.316

4.  Factors Associated With End-of-Life Planning in Huntington Disease.

Authors:  Nancy R Downing; Siera Goodnight; Sena Chae; Joel S Perlmutter; Michael McCormack; Elizabeth Hahn; Stacey K Barton; Noelle Carlozzi
Journal:  Am J Hosp Palliat Care       Date:  2017-06-28       Impact factor: 2.500

Review 5.  Late stage care in Huntington's disease.

Authors:  Sheila A Simpson
Journal:  Brain Res Bull       Date:  2006-11-16       Impact factor: 4.077

6.  Huntington's disease: a caring approach to the end of life.

Authors:  Joseph Klager; Ayana Duckett; Susan Sandler; Carol Moskowitz
Journal:  Care Manag J       Date:  2008

7.  The influence of gender on phenotype and disease progression in patients with Huntington's disease.

Authors:  Daniel Zielonka; Johan Marinus; Raymund A C Roos; Giuseppe De Michele; Stefano Di Donato; Hein Putter; Jerzy Marcinkowski; Ferdinando Squitieri; Anna Rita Bentivoglio; G Bernhard Landwehrmeyer
Journal:  Parkinsonism Relat Disord       Date:  2012-10-25       Impact factor: 4.891

8.  Predictors of nursing home placement in Huntington disease.

Authors:  V L Wheelock; T Tempkin; K Marder; M Nance; R H Myers; H Zhao; E Kayson; C Orme; I Shoulson
Journal:  Neurology       Date:  2003-03-25       Impact factor: 9.910

Review 9.  Huntington's disease: a clinical review.

Authors:  Raymund A C Roos
Journal:  Orphanet J Rare Dis       Date:  2010-12-20       Impact factor: 4.123

10.  Planning for an uncertain future in progressive neurological disease: a qualitative study of patient and family decision-making with a focus on eating and drinking.

Authors:  Gemma Clarke; Elizabeth Fistein; Anthony Holland; Jake Tobin; Sam Barclay; Stephen Barclay
Journal:  BMC Neurol       Date:  2018-08-16       Impact factor: 2.474

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  3 in total

1.  Using a Clinical Formulation to Understand Psychological Distress in People Affected by Huntington's Disease: A Descriptive, Evidence-Based Model.

Authors:  Maria Dale; Ashleigh Wood; Nicolò Zarotti; Fiona Eccles; Sarah Gunn; Reza Kiani; Amanda Mobley; Noelle Robertson; Jane Simpson
Journal:  J Pers Med       Date:  2022-07-27

2.  Patient perspectives on advance euthanasia directives in Huntington's disease. A qualitative interview study.

Authors:  Marina R Ekkel; Marja F I A Depla; Els M L Verschuur; Ruth B Veenhuizen; Cees M P M Hertogh; Bregje D Onwuteaka-Philipsen
Journal:  BMC Med Ethics       Date:  2022-10-10       Impact factor: 2.834

3.  More than Just a Brain Disorder: A Five-Point Manifesto for Psychological Care for People with Huntington's Disease.

Authors:  Nicolò Zarotti; Maria Dale; Fiona J R Eccles; Jane Simpson
Journal:  J Pers Med       Date:  2022-01-07
  3 in total

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