Literature DB >> 33435156

The Role of Noncoding RNAs in the Regulation of Anoikis and Anchorage-Independent Growth in Cancer.

Han Yeoung Lee1, Seung Wan Son1, Sokviseth Moeng1, Soo Young Choi1, Jong Kook Park1.   

Abstract

Cancer is a global health concern, and the prognosis of patients with cancer is associated with metastasis. Multistep processes are involved in cancer metastasis. Accumulating evidence has shown that cancer cells acquire the capacity of anoikis resistance and anchorage-independent cell growth, which are critical prerequisite features of metastatic cancer cells. Multiple cellular factors and events, such as apoptosis, survival factors, cell cycle, EMT, stemness, autophagy, and integrins influence the anoikis resistance and anchorage-independent cell growth in cancer. Noncoding RNAs (ncRNAs), such as microRNAs (miRNAs) and long noncoding RNAs (lncRNAs), are dysregulated in cancer. They regulate cellular signaling pathways and events, eventually contributing to cancer aggressiveness. This review presents the role of miRNAs and lncRNAs in modulating anoikis resistance and anchorage-independent cell growth. We also discuss the feasibility of ncRNA-based therapy and the natural features of ncRNAs that need to be contemplated for more beneficial therapeutic strategies against cancer.

Entities:  

Keywords:  anchorage-independent growth; anoikis; apoptosis; cancer; long noncoding RNA; metastasis; microRNA; noncoding RNA

Mesh：

Substances：

Year:  2021        PMID： 33435156      PMCID： PMC7827914          DOI： 10.3390/ijms22020627

Source DB:  PubMed          Journal:  Int J Mol Sci        ISSN： 1422-0067            Impact factor:   5.923


  292 in total

1.  Tumour invasion and metastasis initiated by microRNA-10b in breast cancer.

Authors:  Li Ma; Julie Teruya-Feldstein; Robert A Weinberg
Journal:  Nature       Date:  2007-09-26       Impact factor: 49.962

2.  The Alternative Splicing of Cytoplasmic Polyadenylation Element Binding Protein 2 Drives Anoikis Resistance and the Metastasis of Triple Negative Breast Cancer.

Authors:  Ryan M Johnson; Ngoc T Vu; Brian P Griffin; Amanda E Gentry; Kellie J Archer; Charles E Chalfant; Margaret A Park
Journal:  J Biol Chem       Date:  2015-08-24       Impact factor: 5.157

3.  The role of miR-766-5p in cell migration and invasion in colorectal cancer.

Authors:  Bin Jia; Lei Xia; Fang Cao
Journal:  Exp Ther Med       Date:  2018-01-08       Impact factor: 2.447

4.  TOPK promotes epithelial-mesenchymal transition and invasion of breast cancer cells through upregulation of TBX3 in TGF-β1/Smad signaling.

Authors:  Young-Ju Lee; Jung-Hwan Park; Sang-Muk Oh
Journal:  Biochem Biophys Res Commun       Date:  2019-11-20       Impact factor: 3.575

5.  Anoikis resistance: an essential prerequisite for tumor metastasis.

Authors:  Yong-Nyun Kim; Kyung Hee Koo; Jee Young Sung; Un-Jung Yun; Hyeryeong Kim
Journal:  Int J Cell Biol       Date:  2012-02-23

6.  Critical role of miR-10b in B-RafV600E dependent anchorage independent growth and invasion of melanoma cells.

Authors:  Ila Datar; Gardiyawasam Kalpana; Jungmin Choi; Tupa Basuroy; Robert Trumbly; Sri Krishna Chaitanya Arudra; Michael D McPhee; Ivana de la Serna; Kam C Yeung
Journal:  PLoS One       Date:  2019-04-17       Impact factor: 3.240

7.  Overexpression of SNHG12 regulates the viability and invasion of renal cell carcinoma cells through modulation of HIF1α.

Authors:  Qiguang Chen; Wei Zhou; Shu-Qi Du; Da-Xin Gong; Jun Li; Jian-Bin Bi; Zhen-Hua Li; Zhe Zhang; Ze-Liang Li; Xian-Kui Liu; Chui-Ze Kong
Journal:  Cancer Cell Int       Date:  2019-05-14       Impact factor: 5.722

Review 8.  Pan-cancer analysis of long non-coding RNA NEAT1 in various cancers.

Authors:  Shufen Li; Jingming Li; Chen Chen; Rongsheng Zhang; Kankan Wang
Journal:  Genes Dis       Date:  2017-11-21

9.  Long Non-Coding RNA LEF1-AS1 Promotes Migration, Invasion and Metastasis of Colon Cancer Cells Through miR-30-5p/SOX9 Axis.

Authors:  Ting Sun; Zhexian Liu; Rui Zhang; Siping Ma; Tao Lin; Yanxi Li; Shihua Yang; Wanchuan Zhang; Yongpeng Wang
Journal:  Onco Targets Ther       Date:  2020-04-07       Impact factor: 4.147

Review 10.  Long Non-Coding RNA HOTAIR in Breast Cancer Therapy.

Authors:  Monica Cantile; Maurizio Di Bonito; Margherita Cerrone; Francesca Collina; Michelino De Laurentiis; Gerardo Botti
Journal:  Cancers (Basel)       Date:  2020-05-09       Impact factor: 6.639
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  5 in total

Review 1.  Long Noncoding RNA and Circular RNA: Two Rising Stars in Regulating Epithelial-Mesenchymal Transition of Pancreatic Cancer.

Authors:  Xiaoying Yang; Cheng Qin; Bangbo Zhao; Tianhao Li; Yuanyang Wang; Zeru Li; Tianyu Li; Weibin Wang
Journal:  Front Oncol       Date:  2022-06-03       Impact factor: 5.738

Review 2.  Noncoding RNAs Associated with Therapeutic Resistance in Pancreatic Cancer.

Authors:  Seung Wan Son; Mun Gyu Song; Ba Da Yun; Jong Kook Park
Journal:  Biomedicines       Date:  2021-03-07

Review 3.  The Hypoxia-Long Noncoding RNA Interaction in Solid Cancers.

Authors:  Seung Wan Son; Ba Da Yun; Mun Gyu Song; Jin Kyeong Lee; Soo Young Choi; Hyo Jeong Kuh; Jong Kook Park
Journal:  Int J Mol Sci       Date:  2021-07-06       Impact factor: 5.923

Review 4.  Oncogenic Role of Exosomal Circular and Long Noncoding RNAs in Gastrointestinal Cancers.

Authors:  Ba Da Yun; Ye Ji Choi; Seung Wan Son; Gabriel Adelman Cipolla; Fernanda Costa Brandão Berti; Danielle Malheiros; Tae-Jin Oh; Hyo Jeong Kuh; Soo Young Choi; Jong Kook Park
Journal:  Int J Mol Sci       Date:  2022-01-15       Impact factor: 5.923

Review 5.  Lemongrass Essential Oil Components with Antimicrobial and Anticancer Activities.

Authors:  Mohammad Mukarram; Sadaf Choudhary; Mo Ahamad Khan; Palmiro Poltronieri; M Masroor A Khan; Jamin Ali; Daniel Kurjak; Mohd Shahid
Journal:  Antioxidants (Basel)       Date:  2021-12-22
  5 in total

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