M Hijazi1, S D Mihailescu2,3, J Horion4, A Goldenberg5, J P Marie6. 1. Department of Otorhinolaryngology-Head and Neck Surgery and Audiophonology, Eure-Seine Hospital, Evreux, France. Hijazi.mohamad@outlook.com. 2. Department of Biostatistics, Rouen University Hospital, Rouen, France. 3. CIRCE NEV (Innovation, Clinical Research and Educational Unit Normandie Evreux Vernon), Eure-Seine Hospital, Evreux, France. 4. Department of Radiology, University Hospital, Rouen, France. 5. Department of Genetics and Reference Center for Developmental Disorders, Normandy Center for Genomic and Personalized Medicine, UNIROUEN, Normandie Univ, Inserm U1245 and Rouen University Hospital, Rouen, France. 6. Department of Otorhinolaryngology-Head and Neck Surgery and Audiophonology, University Hospital, Rouen, France.
Abstract
PURPOSE: To evaluate short and long term results of stapes surgery in patients with osteogenesis imperfecta (OI), METHODS: Retrospective case series of 18 primary stapes surgeries performed on 11 hearing-impaired OI patients with evidence of stapes fixation, in a Tertiary referral center. We analysed pre-operative and post-operative hearing results at 1 month and at least 1 year RESULTS: The main operative findings were stapes fixation, thickened footplate and fragile or fractured stapes crura. No revision surgery was necessary. Hearing improvement was achieved in 94% of the cases. We obtained an air-bone gap closure to within 10 dB in 46% of the cases and to within 15 dB in 92% of the cases at 1-year follow-up. The mean hearing gain in air conduction (at 0.5, 1, 2 and 4 kHz) was 18.4 dB at 1 month and 22.4 dB at 1 year. CONCLUSION: Stapes surgery in OI gives good results with few complications in our series. A hearing gain is often obtained in spite of the sensorineural hearing loss caused by the natural progression of the disease.
PURPOSE: To evaluate short and long term results of stapes surgery in patients with osteogenesis imperfecta (OI), METHODS: Retrospective case series of 18 primary stapes surgeries performed on 11 hearing-impaired OIpatients with evidence of stapes fixation, in a Tertiary referral center. We analysed pre-operative and post-operative hearing results at 1 month and at least 1 year RESULTS: The main operative findings were stapes fixation, thickened footplate and fragile or fractured stapes crura. No revision surgery was necessary. Hearing improvement was achieved in 94% of the cases. We obtained an air-bone gap closure to within 10 dB in 46% of the cases and to within 15 dB in 92% of the cases at 1-year follow-up. The mean hearing gain in air conduction (at 0.5, 1, 2 and 4 kHz) was 18.4 dB at 1 month and 22.4 dB at 1 year. CONCLUSION: Stapes surgery in OI gives good results with few complications in our series. A hearing gain is often obtained in spite of the sensorineural hearing loss caused by the natural progression of the disease.
Authors: Freya K R Swinnen; Ingeborg J M Dhooge; Paul J Coucke; Patrizia D'Eufemia; Francesco Zardo; Ton J T M Garretsen; Cor W R J Cremers; Els M R De Leenheer Journal: Otol Neurotol Date: 2012-02 Impact factor: 2.311
Authors: Freya K R Swinnen; Els M R De Leenheer; Paul J Coucke; Cor W R J Cremers; Ingeborg J M Dhooge Journal: Audiol Neurootol Date: 2012-03-07 Impact factor: 1.854