Literature DB >> 33430601

Tubulin Detyrosination: An Emerging Therapeutic Target in Hypertrophic Cardiomyopathy.

Kenneth B Margulies1,2,3, Benjamin L Prosser2,3,4.   

Abstract

Entities:  

Keywords:  Editorials; cardiomegaly; cardiomyopathy, hypertrophic; mutation; myosins

Mesh：

Substances：

Year:  2021        PMID： 33430601      PMCID： PMC7855801          DOI： 10.1161/CIRCHEARTFAILURE.120.008006

Source DB:  PubMed          Journal:  Circ Heart Fail        ISSN： 1941-3289            Impact factor:   10.447


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  8 in total

1.  Parthenolide induces a distinct pattern of oxidative stress in cardiac myocytes.

Authors:  Mazen Kurdi; Mark C Bowers; Joana Dado; George W Booz
Journal:  Free Radic Biol Med       Date:  2006-11-15       Impact factor: 7.376

2.  Detyrosinated microtubules buckle and bear load in contracting cardiomyocytes.

Authors:  Patrick Robison; Matthew A Caporizzo; Hossein Ahmadzadeh; Alexey I Bogush; Christina Yingxian Chen; Kenneth B Margulies; Vivek B Shenoy; Benjamin L Prosser
Journal:  Science       Date:  2016-04-22       Impact factor: 47.728

3.  Depletion of Vasohibin 1 Speeds Contraction and Relaxation in Failing Human Cardiomyocytes.

Authors:  Christina Yingxian Chen; Alexander K Salomon; Matthew A Caporizzo; Sam Curry; Neil A Kelly; Kenneth Bedi; Alexey I Bogush; Elisabeth Krämer; Saskia Schlossarek; Philip Janiak; Marie-Jo Moutin; Lucie Carrier; Kenneth B Margulies; Benjamin L Prosser
Journal:  Circ Res       Date:  2020-04-10       Impact factor: 17.367

Review 4.  Surgery insight: Septal myectomy for obstructive hypertrophic cardiomyopathy--the Mayo Clinic experience.

Authors:  Joseph A Dearani; Steve R Ommen; Bernard J Gersh; Hartzell V Schaff; Gordon K Danielson
Journal:  Nat Clin Pract Cardiovasc Med       Date:  2007-09

5.  Microtubules Increase Diastolic Stiffness in Failing Human Cardiomyocytes and Myocardium.

Authors:  Matthew A Caporizzo; Christina Yingxian Chen; Ken Bedi; Kenneth B Margulies; Benjamin L Prosser
Journal:  Circulation       Date:  2020-01-16       Impact factor: 29.690

6.  Microtubules regulate cardiomyocyte transversal Young's modulus.

Authors:  Pamela Swiatlowska; Jose L Sanchez-Alonso; Peter T Wright; Pavel Novak; Julia Gorelik
Journal:  Proc Natl Acad Sci U S A       Date:  2020-01-27       Impact factor: 11.205

7.  Proteomic and Functional Studies Reveal Detyrosinated Tubulin as Treatment Target in Sarcomere Mutation-Induced Hypertrophic Cardiomyopathy.

Authors:  Jolanda van der Velden; Diederik W D Kuster; Maike Schuldt; Jiayi Pei; Magdalena Harakalova; Larissa M Dorsch; Saskia Schlossarek; Michal Mokry; Jaco C Knol; Thang V Pham; Tim Schelfhorst; Sander R Piersma; Cris Dos Remedios; Michiel Dalinghaus; Michelle Michels; Folkert W Asselbergs; Marie-Jo Moutin; Lucie Carrier; Connie R Jimenez
Journal:  Circ Heart Fail       Date:  2021-01-12       Impact factor: 8.790

8.  Suppression of detyrosinated microtubules improves cardiomyocyte function in human heart failure.

Authors:  Christina Yingxian Chen; Matthew A Caporizzo; Kenneth Bedi; Alexia Vite; Alexey I Bogush; Patrick Robison; Julie G Heffler; Alex K Salomon; Neil A Kelly; Apoorva Babu; Michael P Morley; Kenneth B Margulies; Benjamin L Prosser
Journal:  Nat Med       Date:  2018-06-11       Impact factor: 53.440
  8 in total
  2 in total

Review 1.  Cardiomyocyte Microtubules: Control of Mechanics, Transport, and Remodeling.

Authors:  Keita Uchida; Emily A Scarborough; Benjamin L Prosser
Journal:  Annu Rev Physiol       Date:  2021-10-06       Impact factor: 22.163

Review 2.  The microtubule cytoskeleton in cardiac mechanics and heart failure.

Authors:  Matthew A Caporizzo; Benjamin L Prosser
Journal:  Nat Rev Cardiol       Date:  2022-04-19       Impact factor: 49.421
  2 in total

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