Literature DB >> 33430283

On Pilot Massive COVID-19 Testing by Antigen Tests in Europe. Case Study: Slovakia.

Jaroslav Frnda1, Marek Durica1.   

Abstract

This paper provides a summary of mass COVID-19 testing of almost the entire population in Slovakia by antigen tests. We focused on the results delivered by two testing rounds and analyzed the benefits and weaknesses of such type of testing. We prepared mathematical models to critically examine the effectiveness of the testing, and we also estimated the number of potentially sick people that would become infected by those marked as positives by antigen tests. Our calculations have proven that antigen testing in hotspots can flatten the curve of daily newly reported cases significantly, but in regions with low-risk of COVID-19, the benefit of such testing is questionable. As for the regions with low infection rates, we could only estimate the proportion of true and false-positive cases because the national health authority had not validated the results by RT-PCR tests. Therefore, this work can serve as an introductory study on the first nationwide testing by antigen tests in Europe.

Entities:  

Keywords:  COVID-19; estimation of infection rate; nationwide antigen testing

Year:  2021        PMID: 33430283      PMCID: PMC7839004          DOI: 10.3390/idr13010007

Source DB:  PubMed          Journal:  Infect Dis Rep        ISSN: 2036-7430


  14 in total

1.  Covid-19: identifying and isolating asymptomatic people helped eliminate virus in Italian village.

Authors:  Michael Day
Journal:  BMJ       Date:  2020-03-23

2.  Fast coronavirus tests: what they can and can't do.

Authors:  Giorgia Guglielmi
Journal:  Nature       Date:  2020-09       Impact factor: 49.962

3.  Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR.

Authors:  Victor M Corman; Olfert Landt; Marco Kaiser; Richard Molenkamp; Adam Meijer; Daniel Kw Chu; Tobias Bleicker; Sebastian Brünink; Julia Schneider; Marie Luisa Schmidt; Daphne Gjc Mulders; Bart L Haagmans; Bas van der Veer; Sharon van den Brink; Lisa Wijsman; Gabriel Goderski; Jean-Louis Romette; Joanna Ellis; Maria Zambon; Malik Peiris; Herman Goossens; Chantal Reusken; Marion Pg Koopmans; Christian Drosten
Journal:  Euro Surveill       Date:  2020-01

4.  Estimating unobserved SARS-CoV-2 infections in the United States.

Authors:  T Alex Perkins; Sean M Cavany; Sean M Moore; Rachel J Oidtman; Anita Lerch; Marya Poterek
Journal:  Proc Natl Acad Sci U S A       Date:  2020-08-21       Impact factor: 11.205

5.  Estimation of COVID-19 outbreak size in Italy.

Authors:  Ashleigh R Tuite; Victoria Ng; Erin Rees; David Fisman
Journal:  Lancet Infect Dis       Date:  2020-03-19       Impact factor: 25.071

Review 6.  In vitro diagnostics of coronavirus disease 2019: Technologies and application.

Authors:  Chih-Cheng Lai; Cheng-Yi Wang; Wen-Chien Ko; Po-Ren Hsueh
Journal:  J Microbiol Immunol Infect       Date:  2020-06-05       Impact factor: 4.399

7.  Comparison of automated SARS-CoV-2 antigen test for COVID-19 infection with quantitative RT-PCR using 313 nasopharyngeal swabs, including from seven serially followed patients.

Authors:  Yosuke Hirotsu; Makoto Maejima; Masahiro Shibusawa; Yuki Nagakubo; Kazuhiro Hosaka; Kenji Amemiya; Hitomi Sueki; Miyoko Hayakawa; Hitoshi Mochizuki; Toshiharu Tsutsui; Yumiko Kakizaki; Yoshihiro Miyashita; Shintaro Yagi; Satoshi Kojima; Masao Omata
Journal:  Int J Infect Dis       Date:  2020-08-12       Impact factor: 3.623

8.  Measuring the impact of COVID-19 confinement measures on human mobility using mobile positioning data. A European regional analysis.

Authors:  Carlos Santamaria; Francesco Sermi; Spyridon Spyratos; Stefano Maria Iacus; Alessandro Annunziato; Dario Tarchi; Michele Vespe
Journal:  Saf Sci       Date:  2020-09-12       Impact factor: 4.877

9.  Substantial undocumented infection facilitates the rapid dissemination of novel coronavirus (SARS-CoV-2).

Authors:  Ruiyun Li; Sen Pei; Bin Chen; Yimeng Song; Tao Zhang; Wan Yang; Jeffrey Shaman
Journal:  Science       Date:  2020-03-16       Impact factor: 47.728

10.  Exploring the growth of COVID-19 cases using exponential modelling across 42 countries and predicting signs of early containment using machine learning.

Authors:  Dharun Kasilingam; Sakthivel Puvaneswaran Sathiya Prabhakaran; Dinesh Kumar Rajendran; Varthini Rajagopal; Thangaraj Santhosh Kumar; Ajitha Soundararaj
Journal:  Transbound Emerg Dis       Date:  2020-09-17       Impact factor: 4.521

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  11 in total

Review 1.  Rapid, point-of-care antigen tests for diagnosis of SARS-CoV-2 infection.

Authors:  Jacqueline Dinnes; Pawana Sharma; Sarah Berhane; Susanna S van Wyk; Nicholas Nyaaba; Julie Domen; Melissa Taylor; Jane Cunningham; Clare Davenport; Sabine Dittrich; Devy Emperador; Lotty Hooft; Mariska Mg Leeflang; Matthew Df McInnes; René Spijker; Jan Y Verbakel; Yemisi Takwoingi; Sian Taylor-Phillips; Ann Van den Bruel; Jonathan J Deeks
Journal:  Cochrane Database Syst Rev       Date:  2022-07-22

Review 2.  Rapid Antigen Assays for SARS-CoV-2: Promise and Peril.

Authors:  Thao T Truong; Jennifer Dien Bard; Susan M Butler-Wu
Journal:  Clin Lab Med       Date:  2022-03-04       Impact factor: 2.172

3.  Heterogeneity in testing for infectious diseases.

Authors:  Christian Berrig; Viggo Andreasen; Bjarke Frost Nielsen
Journal:  R Soc Open Sci       Date:  2022-05-18       Impact factor: 3.653

Review 4.  Testing at scale during the COVID-19 pandemic.

Authors:  Tim R Mercer; Marc Salit
Journal:  Nat Rev Genet       Date:  2021-05-04       Impact factor: 59.581

5.  Perception of COVID-19 Testing in the Entire Population.

Authors:  Beata Gavurova; Viera Ivankova; Martin Rigelsky; Zdenek Caha; Tawfik Mudarri
Journal:  Front Public Health       Date:  2022-02-10

6.  Choice of SARS-CoV-2 diagnostic test: challenges and key considerations for the future.

Authors:  Fausto Baldanti; Nirmal K Ganguly; Guiqiang Wang; Martin Möckel; Luke A O'Neill; Harald Renz; Carlos Eduardo Dos Santos Ferreira; Kazuhiro Tateda; Barbara Van Der Pol
Journal:  Crit Rev Clin Lab Sci       Date:  2022-03-15       Impact factor: 6.250

Review 7.  Effectiveness of rapid antigen testing for screening of asymptomatic individuals to limit the transmission of SARS-CoV-2: A rapid review.

Authors:  Kieran A Walsh; Natasha Broderick; Susan Ahern; Christopher G Fawsitt; Katie M O'Brien; Marie Carrigan; Patricia Harrington; Michelle O'Neill; Susan M Smith; Susan Spillane; Conor Teljeur; Máirín Ryan
Journal:  Rev Med Virol       Date:  2022-03-29       Impact factor: 11.043

8.  Comparison of SARS-CoV-2 Detection by Rapid Antigen and by Three Commercial RT-qPCR Tests: A Study from Martin University Hospital in Slovakia.

Authors:  Zuzana Dankova; Elena Novakova; Maria Skerenova; Veronika Holubekova; Vincent Lucansky; Dana Dvorska; Dusan Brany; Zuzana Kolkova; Jan Strnadel; Sandra Mersakova; Katarina Janikova; Marek Samec; Michal Pokusa; Martin Petras; Miroslava Sarlinova; Ivana Kasubova; Dusan Loderer; Vladimira Sadlonova; Jana Kompanikova; Nina Kotlebova; Adriana Kompanikova; Martina Hrnciarova; Andrea Stanclova; Martina Antosova; Anton Dzian; Vladimir Nosal; Ivan Kocan; Dalibor Murgas; Dusan Krkoska; Andrea Calkovska; Erika Halasova
Journal:  Int J Environ Res Public Health       Date:  2021-07-01       Impact factor: 3.390

9.  Accuracy of novel antigen rapid diagnostics for SARS-CoV-2: A living systematic review and meta-analysis.

Authors:  Lukas E Brümmer; Stephan Katzenschlager; Mary Gaeddert; Christian Erdmann; Stephani Schmitz; Marc Bota; Maurizio Grilli; Jan Larmann; Markus A Weigand; Nira R Pollock; Aurélien Macé; Sergio Carmona; Stefano Ongarello; Jilian A Sacks; Claudia M Denkinger
Journal:  PLoS Med       Date:  2021-08-12       Impact factor: 11.069

10.  Prospective evaluation of the point-of-care use of a rapid antigenic SARS-CoV-2 immunochromatographic test in a paediatric emergency department.

Authors:  Quentin Ollier; Sylvie Pillet; Olivier Mory; Julie Gagnaire; Charlotte Thuiller; Nadine Annino; Amandine Gagneux-Brunon; Elisabeth Botelho-Nevers; Thomas Bourlet; Bruno Pozzetto; Aymeric Cantais
Journal:  Clin Microbiol Infect       Date:  2022-01-20       Impact factor: 13.310

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