Literature DB >> 33428659

Results of a previously unreported extravesical ureteroneocystostomy technique without ureteral stenting in 500 consecutive kidney transplant recipients.

Gaetano Ciancio1,2,3, Ahmed Farag1,3,4, Javier Gonzalez5, Paolo Vincenzi1,3, Jeffrey J Gaynor1,3.   

Abstract

Urologic complications can still occur following kidney transplantation, sometimes requiring multiple radiological and/or surgical procedures to fully correct the problem. Previously proposed extravesical ureteral reimplantation techniques still carry non-negligible risks of the patient developing urologic complications. About 10 years ago, a new set of modifications to the Lich-Gregoir technique was developed at our center, with the goal of further minimizing the occurrence of urologic complications, and without the need for initial ureteral stent placement. It was believed that an improvement in the surgical technique to minimize the risk of developing urologic complications was possible without the need for stent placement at the time of transplant. In this report, we describe the advantages of this technique (i.e., mobilized bladder, longer spatulation of the ureter, inclusion of bladder mucosa with detrusor muscle layer in the ureteral anastomosis, and use of a right angle clamp in the ureteral orifice to ensure that it does not become stenosed). We also retrospectively report our experience in using this technique among 500 consecutive (prospectively followed) kidney transplant recipients transplanted at our center since 2014. During the first 12mo post-transplant, only 1.4%(7/500) of patients developed a urologic complication; additionally, only 1.0%(5/500) required surgical repair of their original ureteroneocystostomy. Five patients(1.0%) developed a urinary leak, with 3/5 having distal ureteral necrosis, and 1/5 subsequently developing a ureteral stricture. Two other patients developed ureteral stenosis, one due to stricture and one due to ureteral stones. These overall results are excellent when compared with other reports in the literature, especially those in which routine stenting was performed. In summary, we believe that the advantages in using this modified extravesical ureteroneocystostomy technique clearly help in lowering the early post-transplant risk of developing urologic complications. Importantly, these results were achieved without the need for ureteral stent placement at the time of transplant.

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Year:  2021        PMID: 33428659      PMCID: PMC7799771          DOI: 10.1371/journal.pone.0244248

Source DB:  PubMed          Journal:  PLoS One        ISSN: 1932-6203            Impact factor:   3.240


  46 in total

1.  Urinary complications after kidney transplantation can be reduced.

Authors:  P Blanchet; Y Hammoudi; P Eschwège; S Droupy; H Bensadoun; C Hiesse; B Charpentier; G Benoit
Journal:  Transplant Proc       Date:  2000-12       Impact factor: 1.066

2.  Long-term comparative outcomes between 2 common ureteroneocystostomy techniques for renal transplantation.

Authors:  Jeffrey L Veale; Jay Yew; David W Gjertson; Craig V Smith; Jennifer S Singer; J Thomas Rosenthal; H Albin Gritsch
Journal:  J Urol       Date:  2007-02       Impact factor: 7.450

Review 3.  Surgical anatomy of the ureter.

Authors:  Rosemarie Fröber
Journal:  BJU Int       Date:  2007-10       Impact factor: 5.588

4.  Urologic complications in more than 2500 kidney transplantations performed at the Saint Barnabas healthcare system.

Authors:  M Whang; M Yballe; S Geffner; H S Fletcher; S Palekar; S Mulgaonkar
Journal:  Transplant Proc       Date:  2011-06       Impact factor: 1.066

5.  The urological complications of renal transplantation: a series of 1535 patients.

Authors:  E H Streeter; D M Little; D W Cranston; P J Morris
Journal:  BJU Int       Date:  2002-11       Impact factor: 5.588

6.  External ureteroneocystostomy and ureteroureterostomy in renal transplantation.

Authors:  J C McDonald; M S Rohr; G D Frentz
Journal:  Ann Surg       Date:  1979-11       Impact factor: 12.969

7.  Ureteroneocystostomy in renal transplantation.

Authors:  M W Woodruff; P Bachrach; A Corica; H E Marden
Journal:  Urology       Date:  1973-05       Impact factor: 2.649

8.  Recurrent urinary tract infections in kidney transplant recipients.

Authors:  Subhashis Mitra; George John Alangaden
Journal:  Curr Infect Dis Rep       Date:  2011-12       Impact factor: 3.725

9.  Parallel incision, unstented extravesical ureteroneocystostomy: followup of 203 kidney transplants.

Authors:  J M Barry; D A Hatch
Journal:  J Urol       Date:  1985-08       Impact factor: 7.450

10.  The Banff 2015 Kidney Meeting Report: Current Challenges in Rejection Classification and Prospects for Adopting Molecular Pathology.

Authors:  A Loupy; M Haas; K Solez; L Racusen; D Glotz; D Seron; B J Nankivell; R B Colvin; M Afrouzian; E Akalin; N Alachkar; S Bagnasco; J U Becker; L Cornell; C Drachenberg; D Dragun; H de Kort; I W Gibson; E S Kraus; C Lefaucheur; C Legendre; H Liapis; T Muthukumar; V Nickeleit; B Orandi; W Park; M Rabant; P Randhawa; E F Reed; C Roufosse; S V Seshan; B Sis; H K Singh; C Schinstock; A Tambur; A Zeevi; M Mengel
Journal:  Am J Transplant       Date:  2017-01       Impact factor: 8.086

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  6 in total

1.  Predictors of Kidney Delayed Graft Function and Its Prognostic Impact following Combined Liver-Kidney Transplantation: A Recent Single-Center Experience.

Authors:  Paolo Vincenzi; Jeffrey J Gaynor; Rodrigo Vianna; Gaetano Ciancio
Journal:  J Clin Med       Date:  2022-05-11       Impact factor: 4.964

2.  Evidence to support a drain-free strategy in kidney transplantation using a retrospective comparison of 500 consecutively transplanted cases at a single center.

Authors:  Ahmed Farag; Jeffrey J Gaynor; Giuseppe Serena; Gaetano Ciancio
Journal:  BMC Surg       Date:  2021-02-05       Impact factor: 2.102

3.  Creating a Single Inflow Orifice From Living Donor Kidney Allografts With Multiple Renal Arteries.

Authors:  Marina M Tabbara; Giselle Guerra; Juliano Riella; Phillipe Abreu; Angel Alvarez; Rodrigo Vianna; Linda Chen; Mahmoud Morsi; Jeffrey J Gaynor; Javier Gonzalez; Gaetano Ciancio
Journal:  Transpl Int       Date:  2022-04-14       Impact factor: 3.842

4.  Complex Vascular Reconstruction of an En Bloc Pediatric Kidney Damaged during Organ Procurement.

Authors:  Juliano Riella; Marina M Tabbara; Phillipe Abreu; Javier Gonzalez; Gaetano Ciancio; José Maria Figueiro
Journal:  Case Rep Transplant       Date:  2022-06-16

5.  Risk Factors for Urologic Complications After Kidney Transplantation and Impact in Graft Survival.

Authors:  Laura Nino-Torres; Andrea Garcia-Lopez; Nasly Patino-Jaramillo; Fernando Giron-Luque; Alejandro Nino-Murcia
Journal:  Res Rep Urol       Date:  2022-09-28

6.  Midline Rotation of the Right Renal Hilum During Hand-Assisted Laparoscopic Living Donor Nephrectomy.

Authors:  Gaetano Ciancio; Ahmed Farag; Jeffrey J Gaynor; Mahmoud Morsi; Linda Chen; George W Burke
Journal:  JSLS       Date:  2021 Apr-Jun       Impact factor: 2.172

  6 in total

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