| Literature DB >> 3342862 |
S Fucharoen1, P Winichagoon, V Thonglairuam, P Wasi.
Abstract
EF Bart's disease is an uncommon form of thalassaemia intermedia resulting from the co-inheritance of alpha-thalassaemia and haemoglobin E in the same subject. Starch-gel electrophoresis revealed two phenotypes in 19 patients with EF Bart's. 16 patients had Hbs CS + E + F + Bart's and the remainder had Hbs E + F + Bart's. DNA mapping and haemoglobin electrophoresis indicated that there are four genotypes, involving 5 abnormal globin genes, responsible for this thalassaemia syndrome.Entities:
Mesh：
Substances：
Year: 1988 PMID： 3342862 DOI： 10.1111/j.1600-0609.1988.tb00800.x
Source DB: PubMed Journal: Eur J Haematol ISSN： 0902-4441 Impact factor: 2.997