Literature DB >> 33427923

Functional outcome after cord detethering in fecally incontinent patients with anorectal malformations.

Emilio Fernandez-Portilla1, Leticia Moreno-Acosta2, Alfredo Dominguez-Muñoz2, Vicente Gonzalez-Carranza3, Fernando Chico-Ponce de Leon3, Roberto Davila-Perez2.   

Abstract

PURPOSE: Tethered cord (TC) occurs in 36% of patients with anorectal malformations (ARMs), for whom the benefit of detethering surgery remains unclear regarding bowel and/or bladder function. This study aimed to examine whether cord detethering could improve fecal and urinary incontinence in these patients.
METHODS: This was a retrospective study of TC patients (>3 years old) with fecal incontinence and ARMs, who underwent detethering surgery between 2016 and 2020 and were followed up for at least 6 months.
RESULTS: Of the 27 included patients, 55% had sacral ratios between 0.4 and 0.7, and in 37% it was < 0.4; the remaining 8% was over 0.7; 52% suffered from colonic hypermotility. After detethering surgery, partial fecal continence was achieved in five patients (18%); total fecal continence, in ten patients (37%); 12 (44%) remained fecally incontinent. Partial urinary continence was obtained in four cases (14%), and the number of patients with total urinary continence rose from 7 (25%) to 15 (55%). Lower extremity symptoms were also improved in 72% of the cases. Patients with colonic hypomotility were found to have a better functional outcome than those with colonic hypermotility (69% vs. 43%, respectively).
CONCLUSION: Our study demonstrated that detethering surgery led to remarkably improved bowel and bladder control in ARM patients with fecal incontinence, which, surprisingly, was not associated with sacral ratio.

Entities:  

Keywords:  Anorectal malformations; Fecal incontinence; Tethered cord; Urinary incontinence

Mesh:

Year:  2021        PMID: 33427923     DOI: 10.1007/s00383-020-04834-6

Source DB:  PubMed          Journal:  Pediatr Surg Int        ISSN: 0179-0358            Impact factor:   1.827


  17 in total

1.  Long-term functional outcome after untethering surgery for a tethered spinal cord in patients with anorectal malformations.

Authors:  Mikihiro Inoue; Keiichi Uchida; Kohei Otake; Yuka Nagano; Tadanobu Shimura; Kiyoshi Hashimoto; Kohei Matsushita; Yuhki Koike; Toshio Matsubara; Masato Kusunoki
Journal:  Pediatr Surg Int       Date:  2017-08-04       Impact factor: 1.827

Review 2.  The tethered spinal cord: diagnosis, significance, and management.

Authors:  D G McLone; F La Marca
Journal:  Semin Pediatr Neurol       Date:  1997-09       Impact factor: 1.636

3.  Screening and Treatment of Tethered Spinal Cord in Anorectal Malformation Patients.

Authors:  Desiree van den Hondel; Cornelius Sloots; T H Rob de Jong; Maarten Lequin; Rene Wijnen
Journal:  Eur J Pediatr Surg       Date:  2015-09-21       Impact factor: 2.191

4.  Tethered cord in children with anorectal malformations with emphasis on rectobladder neck fistula.

Authors:  I Samuk; A Bischoff; E Freud; A Pena
Journal:  Pediatr Surg Int       Date:  2018-11-09       Impact factor: 1.827

5.  The tethered spinal cord: its protean manifestations, diagnosis and surgical correction.

Authors:  H J Hoffman; E B Hendrick; R P Humphreys
Journal:  Childs Brain       Date:  1976

6.  Pathophysiology of "tethered cord syndrome".

Authors:  S Yamada; D E Zinke; D Sanders
Journal:  J Neurosurg       Date:  1981-04       Impact factor: 5.115

Review 7.  Tethered cord syndrome: an updated review.

Authors:  Sean M Lew; Karl F Kothbauer
Journal:  Pediatr Neurosurg       Date:  2007       Impact factor: 1.162

8.  Embryological and clinical implications of the association between anorectal malformations and spinal dysraphisms.

Authors:  Giorgia Totonelli; Raffaella Messina; Francesco Morini; Giovanni Mosiello; Paolo Palma; Marianna Scuglia; Barbara D Iacobelli; Pietro Bagolan
Journal:  Pediatr Surg Int       Date:  2017-06-10       Impact factor: 1.827

9.  Spinal cord anomalies in patients with anorectal malformations without severe sacral abnormalities or meningomyelocele: outcomes after expectant, conservative management.

Authors:  Kristiina Kyrklund; Mikko P Pakarinen; Seppo Taskinen; Reetta Kivisaari; Risto J Rintala
Journal:  J Neurosurg Spine       Date:  2016-07-22

10.  Long-term outcomes of surgical treatment for tethered cord syndrome.

Authors:  Hirotaka Haro; Hiromichi Komori; Atsushi Okawa; Shigenori Kawabata; Kenichi Shinomiya
Journal:  J Spinal Disord Tech       Date:  2004-02
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