Literature DB >> 33427134

Estimated number of N95 respirators needed for healthcare workers in acute-care hospitals during the coronavirus disease 2019 (COVID-19) pandemic.

Patrick T Wedlock1, Kelly J O'Shea1, Madellena Conte2, Sarah M Bartsch1, Samuel L Randall1, Marie C Ferguson1, Sarah N Cox1, Sheryl S Siegmund1, Sarah Kulkarni2, Denis Nash2, Michael Y Lin3, Bruce Y Lee1.   

Abstract

OBJECTIVE: Due to shortages of N95 respirators during the coronavirus disease 2019 (COVID-19) pandemic, it is necessary to estimate the number of N95s required for healthcare workers (HCWs) to inform manufacturing targets and resource allocation.
METHODS: We developed a model to determine the number of N95 respirators needed for HCWs both in a single acute-care hospital and the United States.
RESULTS: For an acute-care hospital with 400 all-cause monthly admissions, the number of N95 respirators needed to manage COVID-19 patients admitted during a month ranges from 113 (95% interpercentile range [IPR], 50-229) if 0.5% of admissions are COVID-19 patients to 22,101 (95% IPR, 5,904-25,881) if 100% of admissions are COVID-19 patients (assuming single use per respirator, and 10 encounters between HCWs and each COVID-19 patient per day). The number of N95s needed decreases to a range of 22 (95% IPR, 10-43) to 4,445 (95% IPR, 1,975-8,684) if each N95 is used for 5 patient encounters. Varying monthly all-cause admissions to 2,000 requires 6,645-13,404 respirators with a 60% COVID-19 admission prevalence, 10 HCW-patient encounters, and reusing N95s 5-10 times. Nationally, the number of N95 respirators needed over the course of the pandemic ranges from 86 million (95% IPR, 37.1-200.6 million) to 1.6 billion (95% IPR, 0.7-3.6 billion) as 5%-90% of the population is exposed (single-use). This number ranges from 17.4 million (95% IPR, 7.3-41 million) to 312.3 million (95% IPR, 131.5-737.3 million) using each respirator for 5 encounters.
CONCLUSIONS: We quantified the number of N95 respirators needed for a given acute-care hospital and nationally during the COVID-19 pandemic under varying conditions.

Entities:  

Year:  2021        PMID: 33427134      PMCID: PMC7884668          DOI: 10.1017/ice.2020.1418

Source DB:  PubMed          Journal:  Infect Control Hosp Epidemiol        ISSN: 0899-823X            Impact factor:   3.254


  20 in total

Review 1.  The Potential Health Care Costs And Resource Use Associated With COVID-19 In The United States.

Authors:  Sarah M Bartsch; Marie C Ferguson; James A McKinnell; Kelly J O'Shea; Patrick T Wedlock; Sheryl S Siegmund; Bruce Y Lee
Journal:  Health Aff (Millwood)       Date:  2020-04-23       Impact factor: 6.301

2.  The annual impact of seasonal influenza in the US: measuring disease burden and costs.

Authors:  Noelle-Angelique M Molinari; Ismael R Ortega-Sanchez; Mark L Messonnier; William W Thompson; Pascale M Wortley; Eric Weintraub; Carolyn B Bridges
Journal:  Vaccine       Date:  2007-04-20       Impact factor: 3.641

3.  Characteristics and Outcomes of 21 Critically Ill Patients With COVID-19 in Washington State.

Authors:  Matt Arentz; Eric Yim; Lindy Klaff; Sharukh Lokhandwala; Francis X Riedo; Maria Chong; Melissa Lee
Journal:  JAMA       Date:  2020-04-28       Impact factor: 56.272

4.  Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China.

Authors:  Dawei Wang; Bo Hu; Chang Hu; Fangfang Zhu; Xing Liu; Jing Zhang; Binbin Wang; Hui Xiang; Zhenshun Cheng; Yong Xiong; Yan Zhao; Yirong Li; Xinghuan Wang; Zhiyong Peng
Journal:  JAMA       Date:  2020-03-17       Impact factor: 56.272

5.  Incidence, clinical outcomes, and transmission dynamics of severe coronavirus disease 2019 in California and Washington: prospective cohort study.

Authors:  Joseph A Lewnard; Vincent X Liu; Michael L Jackson; Mark A Schmidt; Britta L Jewell; Jean P Flores; Chris Jentz; Graham R Northrup; Ayesha Mahmud; Arthur L Reingold; Maya Petersen; Nicholas P Jewell; Scott Young; Jim Bellows
Journal:  BMJ       Date:  2020-05-22

6.  Older age and comorbidity are independent mortality predictors in a large cohort of 1305 COVID-19 patients in Michigan, United States.

Authors:  Z Imam; F Odish; I Gill; D O'Connor; J Armstrong; A Vanood; O Ibironke; A Hanna; A Ranski; A Halalau
Journal:  J Intern Med       Date:  2020-06-22       Impact factor: 13.068

7.  ICU and Ventilator Mortality Among Critically Ill Adults With Coronavirus Disease 2019.

Authors:  Sara C Auld; Mark Caridi-Scheible; James M Blum; Chad Robichaux; Colleen Kraft; Jesse T Jacob; Craig S Jabaley; David Carpenter; Roberta Kaplow; Alfonso C Hernandez-Romieu; Max W Adelman; Greg S Martin; Craig M Coopersmith; David J Murphy
Journal:  Crit Care Med       Date:  2020-09       Impact factor: 9.296

8.  Vaccine Efficacy Needed for a COVID-19 Coronavirus Vaccine to Prevent or Stop an Epidemic as the Sole Intervention.

Authors:  Sarah M Bartsch; Kelly J O'Shea; Marie C Ferguson; Maria Elena Bottazzi; Patrick T Wedlock; Ulrich Strych; James A McKinnell; Sheryl S Siegmund; Sarah N Cox; Peter J Hotez; Bruce Y Lee
Journal:  Am J Prev Med       Date:  2020-07-15       Impact factor: 5.043

9.  Characteristics and Clinical Outcomes of Adult Patients Hospitalized with COVID-19 - Georgia, March 2020.

Authors:  Jeremy A W Gold; Karen K Wong; Christine M Szablewski; Priti R Patel; John Rossow; Juliana da Silva; Pavithra Natarajan; Sapna Bamrah Morris; Robyn Neblett Fanfair; Jessica Rogers-Brown; Beau B Bruce; Sean D Browning; Alfonso C Hernandez-Romieu; Nathan W Furukawa; Mohleen Kang; Mary E Evans; Nadine Oosmanally; Melissa Tobin-D'Angelo; Cherie Drenzek; David J Murphy; Julie Hollberg; James M Blum; Robert Jansen; David W Wright; William M Sewell; Jack D Owens; Benjamin Lefkove; Frank W Brown; Deron C Burton; Timothy M Uyeki; Stephanie R Bialek; Brendan R Jackson
Journal:  MMWR Morb Mortal Wkly Rep       Date:  2020-05-08       Impact factor: 17.586

10.  COVID-19 in 2 Persons with Mild Upper Respiratory Tract Symptoms on a Cruise Ship, Japan.

Authors:  Takeshi Arashiro; Keiichi Furukawa; Akira Nakamura
Journal:  Emerg Infect Dis       Date:  2020-06-17       Impact factor: 6.883

View more
  2 in total

1.  Estimated N95 Respirator Needs for Nonhealthcare Essential Workers in the United States During Communicable Respiratory Infectious Disease Pandemics.

Authors:  Ethan D Fechter-Leggett; Kathleen B Fedan; Jean M Cox-Ganser; Martin I Meltzer; Bishwa B Adhikari; Chad H Dowell
Journal:  Health Secur       Date:  2022-02-01

2.  Maintaining face mask use before and after achieving different COVID-19 vaccination coverage levels: a modelling study.

Authors:  Sarah M Bartsch; Kelly J O'Shea; Kevin L Chin; Ulrich Strych; Marie C Ferguson; Maria Elena Bottazzi; Patrick T Wedlock; Sarah N Cox; Sheryl S Siegmund; Peter J Hotez; Bruce Y Lee
Journal:  Lancet Public Health       Date:  2022-03-08
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.