Literature DB >> 33425913

The Role of Complement in Myocardial Infarction Reperfusion Injury: An Underappreciated Therapeutic Target.

Carl-Wilhelm Vogel1.   

Abstract

This article reviews the pathogenetic role of the complement system in myocardial infarction reperfusion injury. The complement activation pathways involved in myocardial tissue injury are identified, as are the complement-derived effector molecules. The results of past anti-complement therapies are reviewed; as the more recent therapeutic concept of complement depletion with humanized CVF described.
Copyright © 2020 Vogel.

Entities:  

Keywords:  cobra venom factor; complement; complement depletion; humanized cobra venom factor; myocardial infarction; reperfusion injury

Year:  2020        PMID： 33425913      PMCID： PMC7793727          DOI： 10.3389/fcell.2020.606407

Source DB:  PubMed          Journal:  Front Cell Dev Biol        ISSN： 2296-634X


  4 in total

Review 1.  The Role of B Cells in Cardiomyopathy and Heart Failure.

Authors:  Kevin Bermea; Aashik Bhalodia; Angelo Huff; Sylvie Rousseau; Luigi Adamo
Journal:  Curr Cardiol Rep       Date:  2022-06-11       Impact factor: 3.955

2.  MKP-1 Overexpression Reduces Postischemic Myocardial Damage through Attenuation of ER Stress and Mitochondrial Damage.

Authors:  Xiaoling Hou; Lijun Li; Si Chen; Cheng Ge; Mingzhi Shen; Zhenhong Fu
Journal:  Oxid Med Cell Longev       Date:  2021-09-02       Impact factor: 6.543

3.  Cobra Venom Factor Boosts Arteriogenesis in Mice.

Authors:  Philipp Götz; Sharon O Azubuike-Osu; Anna Braumandl; Christoph Arnholdt; Matthias Kübler; Lisa Richter; Manuel Lasch; Lisa Bobrowski; Klaus T Preissner; Elisabeth Deindl
Journal:  Int J Mol Sci       Date:  2022-07-30       Impact factor: 6.208

4.  C3 Deficiency Leads to Increased Angiogenesis and Elevated Pro-Angiogenic Leukocyte Recruitment in Ischemic Muscle Tissue.

Authors:  Philipp Götz; Anna Braumandl; Matthias Kübler; Konda Kumaraswami; Hellen Ishikawa-Ankerhold; Manuel Lasch; Elisabeth Deindl
Journal:  Int J Mol Sci       Date:  2021-05-28       Impact factor: 5.923
  4 in total

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