| Literature DB >> 33425150 |
Abstract
Heerfordt's syndrome is a rare manifestation of sarcoidosis combining uveitis, parotidomegaly, facial paralysis and fever in its classic form. It is an active form of the disease whose diagnosis is facilitated by salivary gland biopsy. We conducted clinical observation of a 17-year-old female patient with uveitis, right parotidomegaly and right facial paralysis characterized by violent onset. After laboratory tests and imaging exam (parotid ultrasound), biopsy of minor salivary glands established the diagnosis of sarcoidosis. A pre-therapeutic assessment allowed for the initiation of oral corticosteroid therapy with favorable outcome and total remission. Heerfordt's syndrome is a rare clinical form of sarcoidosis, with favorable outcome in most cases. Specific diagnostic approach (excluding differential diagnoses, especially the incomplete forms) is necessary, based on therapeutic advances in this area. Copyright: Smail Kharoubi et al.Entities:
Keywords: Granulomatosis; angiotensin; converting enzyme; facial paralysis; parotidomegaly
Year: 2020 PMID: 33425150 PMCID: PMC7755359 DOI: 10.11604/pamj.2020.37.117.25338
Source DB: PubMed Journal: Pan Afr Med J