| Literature DB >> 33424598 |
Andrea Montesel1, Claudio Bucolo2, Victoria Mouvet1, Emmanuelle Moret1, Chiara M Eandi1.
Abstract
We report a case of central retinal artery occlusion (CRAO) in a patient with a previous history of severe COVID-19 disease. This disease has been associated with inflammatory-induced homeostasis changes leading to endothelial dysfunction and a procoagulant state with multi-organ involvement, but the burden of thromboembolic complications in COVID-19 patients is currently unknown. The pathogenesis of retinal artery occlusions is a multifactorial process where inflammation and hypercoagulation state are established risk factors. Even if our experience may represent a coincidental relationship, it is likely that COVID-19 patients could be at risk of developing retinal vascular occlusions. A focused ophthalmological surveillance is advisable to prevent and manage this possible cause of severe vision loss that has an important impact in health care system.Entities:
Keywords: SARS-CoV-2; case report; central retinal artery occlusion; coronavirus disease-2019; severe acute respiratory syndrome coronavirus 2; thrombosis
Year: 2020 PMID: 33424598 PMCID: PMC7785811 DOI: 10.3389/fphar.2020.588384
Source DB: PubMed Journal: Front Pharmacol ISSN: 1663-9812 Impact factor: 5.810