Literature DB >> 33424493

Fallacies and Possible Remedies of the SYNTAX Score.

Yong-Ming He1, Li Shen2, Jun-Bo Ge2.   

Abstract

Quite a few studies have revealed the clinical values regarding the outcome predictions in the cohort of the Synergy between Percutaneous Coronary Intervention with Taxus and Cardiac Surgery (SYNTAX) trial and decision-making with the SYNTAX score. The Evaluation of Xience Everolimus-Eluting Stent Versus Coronary Artery Bypass Surgery for Effectiveness of Left-Main Revascularization (EXCEL) and Nordic-Baltic-British left main revascularization (NOBLE) studies are the largest international randomized studies so far, comparing percutaneous coronary intervention (PCI) and coronary artery bypass graft (CABG) in the treatment of left main coronary artery disease. Unfortunately, both studies failed to validate the value of the SYNTAX score in the selection of revascularization strategies for patients with coronary artery diseases (CAD).. This scenario prompted us to reconsider the inherent fallacies of the SYNTAX score in its derivation. We pointed out eight fallacies for the SYNTAX score in this paper. A recently developed Coronary Artery Tree description and Lesion EvaluaTion (CatLet) score, available at http://www.catletscore.com, a novel angiographic scoring system, could be the remedies for the SYNTAX score.
Copyright © 2020 Yong-Ming He et al.

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Year:  2020        PMID： 33424493      PMCID： PMC7772031          DOI： 10.1155/2020/8822308

Source DB:  PubMed          Journal:  J Interv Cardiol        ISSN： 0896-4327            Impact factor:   2.279


  36 in total

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2.  Reproducibility and factors influencing the assessment of the SYNTAX score in the left main Xience study.

Authors:  Philippe Garot; Muriel Tafflet; Sundar Kumar; Neus Salvatella; Olivier Darremont; Xavier Jouven; Didier Carrié; Thierry Lefèvre; Varvara Russu; Marie-Claude Morice
Journal:  Catheter Cardiovasc Interv       Date:  2012-04-17       Impact factor: 2.692

3.  Anatomical and clinical characteristics to guide decision making between coronary artery bypass surgery and percutaneous coronary intervention for individual patients: development and validation of SYNTAX score II.

Authors:  Vasim Farooq; David van Klaveren; Ewout W Steyerberg; Emanuele Meliga; Yvonne Vergouwe; Alaide Chieffo; Arie Pieter Kappetein; Antonio Colombo; David R Holmes; Michael Mack; Ted Feldman; Marie-Claude Morice; Elisabeth Ståhle; Yoshinobu Onuma; Marie-angèle Morel; Hector M Garcia-Garcia; Gerrit Anne van Es; Keith D Dawkins; Friedrich W Mohr; Patrick W Serruys
Journal:  Lancet       Date:  2013-02-23       Impact factor: 79.321

4.  Percutaneous coronary angioplasty versus coronary artery bypass grafting in treatment of unprotected left main stenosis (NOBLE): a prospective, randomised, open-label, non-inferiority trial.

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Journal:  Lancet       Date:  2016-10-31       Impact factor: 79.321

Review 5.  Lowering risk score profile during PCI in multiple vessel disease is associated with low adverse events: The ERACI risk score.

Authors:  Alfredo E Rodriguez; Carlos Fernandez-Pereira; Juan Mieres; Hernan Pavlovsky; Juan Del Pozo; Alfredo M Rodriguez-Granillo; David Antoniucci
Journal:  Cardiovasc Revasc Med       Date:  2018-02-13

6.  Prognostic value of the SYNTAX score in patients with acute coronary syndromes undergoing percutaneous coronary intervention: analysis from the ACUITY (Acute Catheterization and Urgent Intervention Triage StrategY) trial.

Authors:  Tullio Palmerini; Philippe Genereux; Adriano Caixeta; Ecaterina Cristea; Alexandra Lansky; Roxana Mehran; George Dangas; Dana Lazar; Raquel Sanchez; Martin Fahy; Ke Xu; Gregg W Stone
Journal:  J Am Coll Cardiol       Date:  2011-06-14       Impact factor: 24.094

7.  Trial of everolimus-eluting stents or bypass surgery for coronary disease.

Authors:  Seung-Jung Park; Jung-Min Ahn; Young-Hak Kim; Duk-Woo Park; Sung-Cheol Yun; Jong-Young Lee; Soo-Jin Kang; Seung-Whan Lee; Cheol Whan Lee; Seong-Wook Park; Suk Jung Choo; Cheol Hyun Chung; Jae Won Lee; David J Cohen; Alan C Yeung; Seung Ho Hur; Ki Bae Seung; Tae Hoon Ahn; Hyuck Moon Kwon; Do-Sun Lim; Seung-Woon Rha; Myung-Ho Jeong; Bong-Ki Lee; Damras Tresukosol; Guo Sheng Fu; Tiong Kiam Ong
Journal:  N Engl J Med       Date:  2015-03-16       Impact factor: 91.245

8.  Value of the SYNTAX score for risk assessment in the all-comers population of the randomized multicenter LEADERS (Limus Eluted from A Durable versus ERodable Stent coating) trial.

Authors:  Joanna J Wykrzykowska; Scot Garg; Chrysafios Girasis; Ton de Vries; Marie-Angele Morel; Gerrit-Anne van Es; Pawel Buszman; Axel Linke; Thomas Ischinger; Volker Klauss; Roberto Corti; Franz Eberli; William Wijns; Marie-Claude Morice; Carlo di Mario; Robert Jan van Geuns; Peter Juni; Stephan Windecker; Patrick W Serruys
Journal:  J Am Coll Cardiol       Date:  2010-07-20       Impact factor: 24.094

9.  Assessment of the SYNTAX score in the Syntax study.

Authors:  Patrick W Serruys; Yoshinobu Onuma; Scot Garg; Giovanna Sarno; Marcel van den Brand; Arie-Pieter Kappetein; Nic Van Dyck; Michael Mack; David Holmes; Ted Feldman; Marie-Claude Morice; Antonio Colombo; Eric Bass; Katrin Leadley; Keith D Dawkins; Gerrit-Anne van Es; Marie-Angèle M Morel; Friedrich W Mohr
Journal:  EuroIntervention       Date:  2009-05       Impact factor: 6.534

10.  Inter- and intra-observer variability for the assessment of coronary artery tree description and lesion EvaluaTion (CatLet©) angiographic scoring system in patients with acute myocardial infarction.

Authors:  Jin-Mei Liu; Yang He; Ruo-Ling Teng; Xiao-Dong Qian; Yun-Lang Dai; Jian-Ping Xu; Xin Zhao; Ting-Bo Jiang; Yong-Ming He
Journal:  Chin Med J (Engl)       Date:  2020-11-10       Impact factor: 2.628
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  2 in total

1.  Addressing unmeasured confounding bias with a prior knowledge guided approach: coronary artery bypass grafting (CABG) versus percutaneous coronary intervention (PCI) in patients with stable ischemic heart disease.

Authors:  Lewei Duan; Ming-Sum Lee; Jason N Doctor; John L Adams
Journal:  Health Serv Outcomes Res Methodol       Date:  2022-06-21

2.  The predictive value of CatLet© angiographic scoring system for long-term prognosis in patients with acute myocardial infarction presenting > 12 h after symptom onset.

Authors:  Heng Wang; Yi He; Jia-Li Fan; Xu Li; Bing-Yuan Zhou; Ting-Bo Jiang; Yong-Ming He
Journal:  Front Cardiovasc Med       Date:  2022-09-21
  2 in total

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