S Sabater1, M R Pastor-Juan2, I Andres3, L López-Martinez2, V Lopez-Honrubia3, M I Tercero-Azorin2, M Sevillano3, E Lozano-Setien2, E Jimenez-Jimenez4, R Berenguer3, A Rovirosa5, S Castro-Larefors3, M Magdalena Marti-Laosa3, O Roche6, F Martinez-Terol7, M Arenas8. 1. Department of radiation oncology, Complejo hospitalario universitario de Albacete (CHUA), C/Hnos Falcó 37, 02006 Albacete, Spain. Electronic address: ssabaterm@gmail.com. 2. Department of radiology, Complejo hospitalario universitario de Albacete (CHUA), Albacete, Spain. 3. Department of radiation oncology, Complejo hospitalario universitario de Albacete (CHUA), C/Hnos Falcó 37, 02006 Albacete, Spain. 4. Department of radiation oncology, hospital universitario Santa Lucia, Cartagena, Spain. 5. Gynecological cancer unit, radiation oncology department, ICMHO, IDIBAPS, university of Barcelona, hospital clinic, Barcelona, Spain. 6. Laboratorio de oncología, unidad de medicina molecular, unidad asociada de biomedicina UCLM, unidad asociada al CSIC, centro regional de investigaciones biomédicas, universidad de Castilla-La Mancha, Albacete, Spain; Departamento de ciencias médicas, facultad de medicina de Albacete, universidad de Castilla-La Mancha, Albacete, Spain. 7. Complejo hospitalario universitario de Albacete (CHUA), Albacete, Spain. 8. Department of radiation oncology, hospital universitari Sant Joan, Reus, Spain.
Abstract
PURPOSE: The use of MRI for radiotherapy planning purposes is growing but image acquisition using radiotherapy set-ups has impaired image quality. Whether differences in image acquisition set-up could modify organ contouring has not been evaluated. Therefore, we aimed to evaluate differences in contouring between paired of image sets that were acquired in the same scanning session using different parameters. MATERIAL AND METHODS: Ten patients underwent RT treatment planning with MRI co-registration. MRI was carried out using two different set-ups during the same session, MRI radiotherapy set-ups and MRI diagnostic set-ups. Prostates and rectums were retrospectively contoured in both image sets by 5 radiation oncologists and 4 radiologists. Intra-observer analysis was carried out comparing organ volumes, the Dice coefficient and hausdorff distance values between two contouring rounds. Inter-observer analysis was carried out by comparing individual contours to a generated STAPLE consensus contour, which is considered the gold standard reference. RESULTS: No significant differences were observed between MRI acquisition set-ups. Significant differences were observed for the dice and hausdorff parameters, comparing individual contours to the STAPLE consensus contour, when analysing diagnostic images between rounds, although raw values were similar. CONCLUSION: Prostate and rectum contours did not differ significantly when using diagnostic or radiotherapy MRI acquisition set-ups.
PURPOSE: The use of MRI for radiotherapy planning purposes is growing but image acquisition using radiotherapy set-ups has impaired image quality. Whether differences in image acquisition set-up could modify organ contouring has not been evaluated. Therefore, we aimed to evaluate differences in contouring between paired of image sets that were acquired in the same scanning session using different parameters. MATERIAL AND METHODS: Ten patients underwent RT treatment planning with MRI co-registration. MRI was carried out using two different set-ups during the same session, MRI radiotherapy set-ups and MRI diagnostic set-ups. Prostates and rectums were retrospectively contoured in both image sets by 5 radiation oncologists and 4 radiologists. Intra-observer analysis was carried out comparing organ volumes, the Dice coefficient and hausdorff distance values between two contouring rounds. Inter-observer analysis was carried out by comparing individual contours to a generated STAPLE consensus contour, which is considered the gold standard reference. RESULTS: No significant differences were observed between MRI acquisition set-ups. Significant differences were observed for the dice and hausdorff parameters, comparing individual contours to the STAPLE consensus contour, when analysing diagnostic images between rounds, although raw values were similar. CONCLUSION: Prostate and rectum contours did not differ significantly when using diagnostic or radiotherapy MRI acquisition set-ups.
Authors: Simon K B Spohn; Ilias Sachpazidis; Rolf Wiehle; Benedikt Thomann; August Sigle; Peter Bronsert; Juri Ruf; Matthias Benndorf; Nils H Nicolay; Tanja Sprave; Anca L Grosu; Dimos Baltas; Constantinos Zamboglou Journal: Front Oncol Date: 2021-05-14 Impact factor: 6.244