Literature DB >> 334235

Atypical fibroxanthoma of the skin. Presentation of 5 cases and a review of the literature.

T H Starink, R Hausman, L Van Delden, H Neering.   

Abstract

A typical fibroxanthoma is a solitary tumour of the skin, which occurs mostly on sun-exposed areas in elderly people. The diagnosis can only be made with certainty on the typical histological findings, which suggest a bizarre malignant tumour. Although metastasizing tumours are reported in the literature, the authors believe that the true atypical fibroxanthoma is benign. Correct diagnosis obviates the need for unnecessary radical surgery. The possibility of atypical fibroxanthoma should always be considered when a histologically bizarre tumour is found on sun-damaged or irradiation-damaged skin in elderly patients or on previously traumatized sites. In this paper five cases are added to the 346 cases culled from the literature. Electron microscopic investigations in one case demonstrated cells with delicate cytoplasmic fibrils in small bundles. This does not necessarily suggest filaments of myofibroblasts, as has been previously reported.

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Year:  1977        PMID: 334235     DOI: 10.1111/j.1365-2133.1977.tb15062.x

Source DB:  PubMed          Journal:  Br J Dermatol        ISSN: 0007-0963            Impact factor:   9.302


  5 in total

1.  [Metastasizing atypical fibroxanthoma or malignant fibrous histiocytoma. Clinical and histological picture, nosology, nomenclature].

Authors:  S Hödl
Journal:  Arch Dermatol Res       Date:  1982       Impact factor: 3.017

2.  Incidence and Clinical Features of Rare Cutaneous Malignancies in Olmsted County, Minnesota, 2000 to 2010.

Authors:  Stanislav N Tolkachjov; Adam R Schmitt; John G Muzic; Amy L Weaver; Christian L Baum
Journal:  Dermatol Surg       Date:  2017-01       Impact factor: 3.398

3.  Characterization of a dermal derived malignant mesenchymal tumor arising in ultraviolet irradiated mice.

Authors:  R G Phelps; L E Bernstein; N Harpaz; R E Gordon; F A Cruickshank; E Schwartz
Journal:  Am J Pathol       Date:  1989-07       Impact factor: 4.307

4.  Atypical fibroxanthoma in a young woman: An unusual case presentation.

Authors:  Mark M Melendez; Xiaoti Xu; Steve A McClain; Su-I Daniel Huang
Journal:  Can J Plast Surg       Date:  2007

5.  Atypical fibroxanthoma.

Authors:  Akio Sakamoto
Journal:  Clin Med Oncol       Date:  2008-02-09
  5 in total

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