Literature DB >> 3342338

Cardiovascular effects of microinjection of adenosine into the nucleus tractus solitarius.

R A Barraco1, C J Janusz, P M Polasek, M Parizon, P A Roberts.   

Abstract

Rats were anesthetized with urethane and limited occipital craniotomy was conducted to expose the caudal medulla in the region of the obex. Microinjections of adenosine were made into the nucleus tractus solitarius and heart rate and blood pressure responses recorded. Adenosine produced dose-related decreases in blood pressure and heart rate. The data indicate that adenosine may play a neuromodulatory role in central cardiovascular control areas.

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Year:  1988        PMID： 3342338     DOI： 10.1016/0361-9230(88)90016-0

Source DB:  PubMed          Journal:  Brain Res Bull        ISSN： 0361-9230            Impact factor:   4.077


  10 in total

1.  Vasovagal syncope in patients with reduced left ventricular function.

Authors:  Christopher M Stanton; Phillip A Low; David O Hodge; Win-Kuang Shen
Journal:  Clin Auton Res       Date:  2007-01-09       Impact factor: 4.435

2.  Role of central and peripheral adenosine receptors in the cardiovascular responses to intraperitoneal injections of adenosine A1 and A2A subtype receptor agonists.

Authors:  Charles W Schindler; Marzena Karcz-Kubicha; Eric B Thorndike; Christa E Müller; Srihari R Tella; Sergi Ferré; Steven R Goldberg
Journal:  Br J Pharmacol       Date:  2005-03       Impact factor: 8.739

3.  Physiological roles of A1 and A2A adenosine receptors in regulating heart rate, body temperature, and locomotion as revealed using knockout mice and caffeine.

Authors:  Jiang-Ning Yang; Jiang-Fan Chen; Bertil B Fredholm
Journal:  Am J Physiol Heart Circ Physiol       Date:  2009-02-13       Impact factor: 4.733

4.  Role of brainstem adenosine A1 receptors in the cardiovascular response to hypothalamic defence area stimulation in the anaesthetized rat.

Authors:  J H St Lambert; M R Dashwood; K M Spyer
Journal:  Br J Pharmacol       Date:  1996-01       Impact factor: 8.739

5.  Mice heterozygous for both A1 and A(2A) adenosine receptor genes show similarities to mice given long-term caffeine.

Authors:  Jiang-Ning Yang; Olga Björklund; Karin Lindström-Törnqvist; Eva Lindgren; Therese M Eriksson; Johan Kahlström; Jiang-Fan Chen; Michael A Schwarzschild; Irene Tobler; Bertil B Fredholm
Journal:  J Appl Physiol (1985)       Date:  2008-11-26

6.  Age-dependent changes in adenosine A1 receptor distribution and density within the nucleus tractus solitarii of normotensive and hypertensive rats.

Authors:  D C Carrettiero; D R Fior-Chadi
Journal:  J Neural Transm (Vienna)       Date:  2008-05-08       Impact factor: 3.575

7.  Vasopressin is a major vasoconstrictor involved in hindlimb vascular responses to stimulation of adenosine A(1) receptors in the nucleus of the solitary tract.

Authors:  Joseph M McClure; Noreen F Rossi; Haiping Chen; Donal S O'Leary; Tadeusz J Scislo
Journal:  Am J Physiol Heart Circ Physiol       Date:  2009-09-11       Impact factor: 4.733

8.  The effect of two selective A1 -receptor agonists and the bitopic ligand VCP746 on heart rate and regional vascular conductance in conscious rats.

Authors:  Samantha L Cooper; Julie March; Andrea R Sabbatini; Stephen J Hill; Manuela Jörg; Peter J Scammells; Jeanette Woolard
Journal:  Br J Pharmacol       Date:  2020-01-01       Impact factor: 8.739

9.  Selective deletion of the A1 adenosine receptor abolishes heart-rate slowing effects of intravascular adenosine in vivo.

Authors:  Michael Koeppen; Tobias Eckle; Holger K Eltzschig
Journal:  PLoS One       Date:  2009-08-26       Impact factor: 3.240

Review 10.  Brain stem adenosine receptors modulate centrally mediated hypotensive responses in conscious rats: A review.

Authors:  Noha N Nassar; Abdel A Abdel-Rahman
Journal:  J Adv Res       Date:  2014-12-18       Impact factor: 10.479
  10 in total

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