Guiying Ren1, Juan Qi2, Yuliang Zou3. 1. Department of Medicine, The First Affiliated Hospital of Xi'an Jiaotong University, No. 277 West Yanta Road, Yanta District, Xi'an, Shaanxi 710061, China. 2. Department of Tumor Radiotherapy, The First Affiliated Hospital of Xi'an Jiaotong University, No. 277 West Yanta Road, Yanta District, Xi'an, Shaanxi 710061, China. 3. Department of Medicine, The First Affiliated Hospital of Xi'an Jiaotong University, No. 277 West Yanta Road, Yanta District, Xi'an, Shaanxi 710061, China. Electronic address: zouyuliangfl@126.com.
Abstract
AIMS: Meta-analyses on the association between white rice intake and incident type 2 diabetes (T2D) have been inconsistent. Since the last meta-analysis, more studies have been published with inconsistent results. We aimed to examine the rice-T2D association in Asian populations in an updated meta-analysis. METHODS: We systematically searched the Medline and Embase databases between January 2012 (the date of the first meta-analysis) and December 2020 for prospective studies examining T2D risk and baseline rice intake. Random-effects models were applied to pool relative risks (RRs). Meta regression analyses were used to evaluate the influence of sex. RESULTS: Six articles with eleven comparisons in Asian countries were included in the current meta-analysis. A total of 12,395 incident T2D cases were ascertained from 256,818 participants. The pooled RR was 1.25 (95% confidence interval [CI]: 1.17-1.33) comparing extreme categories of rice intake with higher heterogeneity (I2 = 88%, P < 0.0001). When stratified by sex, the RR was 1.58 (1.26-1.99) among women and 1.30 (0.85-1.98) among men (P-interaction = 0.42). CONCLUSIONS: A positive association between rice intake and incident T2D in Asian populations was found, especially among women.
AIMS: Meta-analyses on the association between white rice intake and incident type 2 diabetes (T2D) have been inconsistent. Since the last meta-analysis, more studies have been published with inconsistent results. We aimed to examine the rice-T2D association in Asian populations in an updated meta-analysis. METHODS: We systematically searched the Medline and Embase databases between January 2012 (the date of the first meta-analysis) and December 2020 for prospective studies examining T2D risk and baseline rice intake. Random-effects models were applied to pool relative risks (RRs). Meta regression analyses were used to evaluate the influence of sex. RESULTS: Six articles with eleven comparisons in Asian countries were included in the current meta-analysis. A total of 12,395 incident T2D cases were ascertained from 256,818 participants. The pooled RR was 1.25 (95% confidence interval [CI]: 1.17-1.33) comparing extreme categories of rice intake with higher heterogeneity (I2 = 88%, P < 0.0001). When stratified by sex, the RR was 1.58 (1.26-1.99) among women and 1.30 (0.85-1.98) among men (P-interaction = 0.42). CONCLUSIONS: A positive association between rice intake and incident T2D in Asian populations was found, especially among women.
Authors: Jiayue Yu; Bhavadharini Balaji; Maria Tinajero; Sarah Jarvis; Tauseef Khan; Sudha Vasudevan; Viren Ranawana; Amudha Poobalan; Shilpa Bhupathiraju; Qi Sun; Walter Willett; Frank B Hu; David J A Jenkins; Viswanathan Mohan; Vasanti S Malik Journal: BMJ Open Date: 2022-09-27 Impact factor: 3.006