| Literature DB >> 33422556 |
Yang Wang1, Bo Hu2, Rongguang Lu2, Fanshu Ma3, Shuang Lv2, Hailing Zhang2, Xue Bai2, Lei Zhang2, Ning Shi3, Xintong Li4, Sining Fan5, Shizhen Lian2, Xijun Yan6, Yanzhu Zhu7.
Abstract
Mink enteritis virus (MEV) is a major pathogen inducing acute hemorrhagic enteritis in mink. This study aims to determine the pathogenicity of the isolated MEV strain (SMPV-11) compared with the attenuated MEV strain (MEV-F61) in the mink. The two MEV strains were inoculated in the two mink groups, respectively. Then the clinical symptom, hematological, serological, and histopathological change were evaluated. Our findings showed that there were differences in the clinical features and pathological changes of the SMPV-11 and MEV-F61 in the mink. It indicates that SMPV-11 is a virulent strain, and it can be the potential MEV vaccine strain in the mink.Entities:
Keywords: Attenuated strain; Clinical feature; Mink enteritis virus; Virulent strain
Mesh：
Year: 2021 PMID： 33422556 DOI： 10.1016/j.virusres.2021.198294
Source DB: PubMed Journal: Virus Res ISSN： 0168-1702 Impact factor: 3.303