Literature DB >> 33422423

GSDME: A Potential Ally in Cancer Detection and Treatment.

J Ibrahim1, E De Schutter2, K Op de Beeck3.   

Abstract

Gasdermin E (GSDME) is an executioner of caspase-3 mediated regulated pyroptosis, and as such plays an important role in several cancers. Recent findings highlighted the potential of GSDME as a biomarker that can be implemented in cancer diagnosis, monitoring, and therapy.
Copyright © 2020 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  GSDME, epigenetics; biomarker; cancer; pyroptosis; therapy

Mesh：

Substances：

Year:  2021        PMID： 33422423     DOI： 10.1016/j.trecan.2020.12.002

Source DB:  PubMed          Journal:  Trends Cancer        ISSN： 2405-8025


  5 in total

Review 1.  Pyroptosis, metabolism, and tumor immune microenvironment.

Authors:  Tiantian Du; Jie Gao; Peilong Li; Yunshan Wang; Qiuchen Qi; Xiaoyan Liu; Juan Li; Chuanxin Wang; Lutao Du
Journal:  Clin Transl Med       Date:  2021-08

2.  DFNA5 regulates immune cells infiltration and exhaustion.

Authors:  Jian Hu; Wenceng Pei; Minren Jiang; Ying Huang; Fuyun Dong; Zhenyou Jiang; Ying Xu; Zihuang Li
Journal:  Cancer Cell Int       Date:  2022-03-05       Impact factor: 5.722

3.  Potential Application of Pyroptosis in Kidney Renal Clear Cell Carcinoma Immunotherapy and Targeted Therapy.

Authors:  Xiaochen Qi; Xiangyu Che; Quanlin Li; Qifei Wang; Guangzhen Wu
Journal:  Front Pharmacol       Date:  2022-06-15       Impact factor: 5.988

4.  BI 2536 induces gasdermin E-dependent pyroptosis in ovarian cancer.

Authors:  Jianting Huo; Yuhong Shen; Yuchen Zhang; Lifei Shen
Journal:  Front Oncol       Date:  2022-08-09       Impact factor: 5.738

5.  The Pyroptosis-Related Signature Predicts Prognosis and Indicates Immune Microenvironment Infiltration in Gastric Cancer.

Authors:  Wei Shao; Zongcheng Yang; Yue Fu; Lixin Zheng; Fen Liu; Li Chai; Jihui Jia
Journal:  Front Cell Dev Biol       Date:  2021-06-11
  5 in total

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