Naga Vaishnavi Gadela1, Devika Umashanker2, Andrew Scatola3, Abhishek Jaiswal4. 1. Department of Internal Medicine, University of Connecticut, Farmington, CT, 06030, USA. 2. Medical Weight Management, Department of Bariatric Surgery, Hartford Hospital, Hartford, CT, 06106, USA. 3. Hartford HealthCare Heart and Vascular Institute, Hartford Hospital, 85 Jefferson Street, Suite#JB208, Hartford, CT, 06106, USA. 4. Hartford HealthCare Heart and Vascular Institute, Hartford Hospital, 85 Jefferson Street, Suite#JB208, Hartford, CT, 06106, USA. Jais.abhishek@gmail.com.
Abstract
PURPOSE OF REVIEW: To discuss clinical outcomes, changes in weight, and weight loss strategies of patients with obesity post left ventricular assist device (LVAD) implantation. RECENT FINDINGS: Despite increased complications in patients with obesity after LVAD implantation, survival is comparable to patients without obesity. A minority of patients with obesity lose significant weight and become eligible for heart transplantation after LVAD implantation. In fact, a great majority of such patients gain weight post-implantation. Obesity by itself should not be considered prohibitive for LVAD therapy but, rather, should be incorporated into the overall risk assessment for LVAD implantation. Concerted strategies should be developed to promote sustainable weight loss in patients with obesity and LVAD to improve quality of life, eligibility, and outcomes after heart transplantation. Investigation of the long-term impact of weight loss on patients with obesity with LVAD is warranted.
PURPOSE OF REVIEW: To discuss clinical outcomes, changes in weight, and weight loss strategies of patients with obesity post left ventricular assist device (LVAD) implantation. RECENT FINDINGS: Despite increased complications in patients with obesity after LVAD implantation, survival is comparable to patients without obesity. A minority of patients with obesity lose significant weight and become eligible for heart transplantation after LVAD implantation. In fact, a great majority of such patients gain weight post-implantation. Obesity by itself should not be considered prohibitive for LVAD therapy but, rather, should be incorporated into the overall risk assessment for LVAD implantation. Concerted strategies should be developed to promote sustainable weight loss in patients with obesity and LVAD to improve quality of life, eligibility, and outcomes after heart transplantation. Investigation of the long-term impact of weight loss on patients with obesity with LVAD is warranted.
Authors: Mandeep R Mehra; Charles E Canter; Margaret M Hannan; Marc J Semigran; Patricia A Uber; David A Baran; Lara Danziger-Isakov; James K Kirklin; Richard Kirk; Sudhir S Kushwaha; Lars H Lund; Luciano Potena; Heather J Ross; David O Taylor; Erik A M Verschuuren; Andreas Zuckermann Journal: J Heart Lung Transplant Date: 2016-01 Impact factor: 10.247
Authors: M A Alpert; B E Terry; M Mulekar; M V Cohen; C V Massey; T M Fan; H Panayiotou; V Mukerji Journal: Am J Cardiol Date: 1997-09-15 Impact factor: 2.778
Authors: Zachary J Ward; Sara N Bleich; Angie L Cradock; Jessica L Barrett; Catherine M Giles; Chasmine Flax; Michael W Long; Steven L Gortmaker Journal: N Engl J Med Date: 2019-12-19 Impact factor: 91.245
Authors: Emer Joyce; Anuradha Lala; Susanna R Stevens; Lauren B Cooper; Omar F AbouEzzeddine; John D Groarke; Justin L Grodin; Eugene Braunwald; Kevin J Anstrom; Margaret M Redfield; Lynne W Stevenson Journal: JACC Heart Fail Date: 2016-12 Impact factor: 12.035
Authors: Faraz S Ahmad; Hongyan Ning; Jonathan D Rich; Clyde W Yancy; Donald M Lloyd-Jones; John T Wilkins Journal: JACC Heart Fail Date: 2016-10-12 Impact factor: 12.035
Authors: Kevin J Clerkin; Yoshifumi Naka; Donna M Mancini; Paolo C Colombo; Veli K Topkara Journal: JACC Heart Fail Date: 2016-09-07 Impact factor: 12.035
Authors: Satish Kenchaiah; Jane C Evans; Daniel Levy; Peter W F Wilson; Emelia J Benjamin; Martin G Larson; William B Kannel; Ramachandran S Vasan Journal: N Engl J Med Date: 2002-08-01 Impact factor: 91.245
Authors: Amanda R Vest; William W Wong; Joronia Chery; Alex Coston; Laura Telfer; Matthew Lawrence; Didjana Celkupa; Michael S Kiernan; Gregory Couper; Masashi Kawabori; Edward Saltzman Journal: Circ Heart Fail Date: 2022-04-05 Impact factor: 10.447
Authors: Daniele Masarone; Andrea Petraio; Antonio Fiorentino; Santo Dellegrottaglie; Fabio Valente; Ernesto Ammendola; Gerardo Nigro; Giuseppe Pacileo Journal: Front Cardiovasc Med Date: 2022-02-16