Literature DB >> 33420601

Chinese Medicine in Fighting against Covid-19: Role and Inspiration.

Jin-Gen Li1, Hao Xu2.   

Abstract

Covid-19 pandemic has caused hundreds of thousands deaths and millions of infections and continued spreading violently. Although researchers are racing to find or develop effective drugs or vaccines, no drugs from modern medical system have been proven effective and the high mutant rates of the virus may lead it resistant to whatever drugs or vaccines developed following modern drug development procedure. Current evidence has demonstrated impressive healing effects of several Chinese medicines (CMs) for Covid-19, which urges us to reflect on the role of CM in the era of modern medicine. Undoubtedly, CM could be promising resources for developing drug candidates for the treatment of Covid-19 in a way similar to the development of artemisinin. But the theory that builds CM, like the emphasis of driving away exogenous pathogen (virus, etc.) by restoring self-healing capacity rather than killing the pathogen directly from the inside and the 'black-box' mode of diagnosing and treating patients, is as important, yet often ignored, an treasure as CM herbs and should be incorporated into modern medicine for future advancement and innovation of medical science.

Entities:  

Keywords:  Chinese medicine; Covid-19; SARS-CoV-2; coronavirus; herbal medicine

Mesh:

Substances:

Year:  2021        PMID: 33420601      PMCID: PMC7792556          DOI: 10.1007/s11655-020-2860-x

Source DB:  PubMed          Journal:  Chin J Integr Med        ISSN: 1672-0415            Impact factor:   1.978


  21 in total

1.  Chinese herbal medicine for coronavirus disease 2019: A systematic review and meta-analysis.

Authors:  Xingjiang Xiong; Pengqian Wang; Kelei Su; William C Cho; Yanwei Xing
Journal:  Pharmacol Res       Date:  2020-07-02       Impact factor: 7.658

2.  Hydroxychloroquine with or without Azithromycin in Mild-to-Moderate Covid-19.

Authors:  Alexandre B Cavalcanti; Fernando G Zampieri; Regis G Rosa; Luciano C P Azevedo; Viviane C Veiga; Alvaro Avezum; Lucas P Damiani; Aline Marcadenti; Letícia Kawano-Dourado; Thiago Lisboa; Debora L M Junqueira; Pedro G M de Barros E Silva; Lucas Tramujas; Erlon O Abreu-Silva; Ligia N Laranjeira; Aline T Soares; Leandro S Echenique; Adriano J Pereira; Flávio G R Freitas; Otávio C E Gebara; Vicente C S Dantas; Remo H M Furtado; Eveline P Milan; Nicole A Golin; Fábio F Cardoso; Israel S Maia; Conrado R Hoffmann Filho; Adrian P M Kormann; Roberto B Amazonas; Monalisa F Bocchi de Oliveira; Ary Serpa-Neto; Maicon Falavigna; Renato D Lopes; Flávia R Machado; Otavio Berwanger
Journal:  N Engl J Med       Date:  2020-07-23       Impact factor: 91.245

3.  Network pharmacology analysis of the therapeutic mechanisms of the traditional Chinese herbal formula Lian Hua Qing Wen in Corona virus disease 2019 (COVID-19), gives fundamental support to the clinical use of LHQW.

Authors:  Shichao Zheng; Jan P Baak; Shuang Li; Wenke Xiao; Hong Ren; Huan Yang; Yanxiong Gan; Chuanbiao Wen
Journal:  Phytomedicine       Date:  2020-09-06       Impact factor: 5.340

4.  Network pharmacology and molecular docking analysis on molecular targets and mechanisms of Huashi Baidu formula in the treatment of COVID-19.

Authors:  Quyuan Tao; Jiaxin Du; Xiantao Li; Jingyan Zeng; Bo Tan; Jianhua Xu; Wenjia Lin; Xin-Lin Chen
Journal:  Drug Dev Ind Pharm       Date:  2020-07-08       Impact factor: 3.225

5.  Treatment effects of xuebijing injection in severe septic patients with disseminated intravascular coagulation.

Authors:  Qin Yin; Chunsheng Li
Journal:  Evid Based Complement Alternat Med       Date:  2014-03-23       Impact factor: 2.629

6.  Traditional Chinese medicine Lianhua Qingwen treating corona virus disease 2019(COVID-19): Meta-analysis of randomized controlled trials.

Authors:  Mengjie Zeng; Linjun Li; Zhiquan Wu
Journal:  PLoS One       Date:  2020-09-11       Impact factor: 3.240

7.  Lianhuaqingwen exerts anti-viral and anti-inflammatory activity against novel coronavirus (SARS-CoV-2).

Authors:  Li Runfeng; Hou Yunlong; Huang Jicheng; Pan Weiqi; Ma Qinhai; Shi Yongxia; Li Chufang; Zhao Jin; Jia Zhenhua; Jiang Haiming; Zheng Kui; Huang Shuxiang; Dai Jun; Li Xiaobo; Hou Xiaotao; Wang Lin; Zhong Nanshan; Yang Zifeng
Journal:  Pharmacol Res       Date:  2020-03-20       Impact factor: 7.658

8.  Toona sinensis Roem tender leaf extract inhibits SARS coronavirus replication.

Authors:  Chung-Jen Chen; Martin Michaelis; Hseng-Kuang Hsu; Chin-Chuan Tsai; Kunder D Yang; Yang-Chang Wu; Jindrich Cinatl; Hans Wilhelm Doerr
Journal:  J Ethnopharmacol       Date:  2008-08-09       Impact factor: 4.360

Review 9.  Can Chinese Medicine Be Used for Prevention of Corona Virus Disease 2019 (COVID-19)? A Review of Historical Classics, Research Evidence and Current Prevention Programs.

Authors:  Hui Luo; Qiao-Ling Tang; Ya-Xi Shang; Shi-Bing Liang; Ming Yang; Nicola Robinson; Jian-Ping Liu
Journal:  Chin J Integr Med       Date:  2020-02-17       Impact factor: 1.978

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  2 in total

1.  Antiviral Effects of Artemisinin and Its Derivatives against SARS-CoV-2 Main Protease: Computational Evidences and Interactions with ACE2 Allelic Variants.

Authors:  Riadh Badraoui; Mongi Saoudi; Walid S Hamadou; Salem Elkahoui; Arif J Siddiqui; Jahoor M Alam; Arshad Jamal; Mohd Adnan; Abdel M E Suliemen; Mousa M Alreshidi; Dharmendra K Yadav; Houcine Naïli; Hmed Ben-Nasr
Journal:  Pharmaceuticals (Basel)       Date:  2022-01-22

2.  Microscopic Mass Spectrometry Imaging Reveals the Distribution of Phytochemicals in the Dried Root of Isatis tinctoria.

Authors:  Li-Xing Nie; Jing Dong; Lie-Yan Huang; Xiu-Yu Qian; Chao-Jie Lian; Shuai Kang; Zhong Dai; Shuang-Cheng Ma
Journal:  Front Pharmacol       Date:  2021-06-29       Impact factor: 5.810

  2 in total

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