Literature DB >> 3342025

The complete sequence of a frog alpha-tubulin gene and its regulated expression in mouse L-cells.

D J Smith1.   

Abstract

A frog alpha-tubulin cDNA and a frog alpha-tubulin gene, closely related to the cDNA, were cloned and sequenced and the structure of the gene deduced. The gene was introduced into mouse L-cells in order to investigate the transcription and regulation of the gene. The gene was transcribed and there was processing of the transcripts. Furthermore, the gene displayed the correct autoregulatory feedback control.

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Year:  1988        PMID: 3342025      PMCID: PMC1148726          DOI: 10.1042/bj2490465

Source DB:  PubMed          Journal:  Biochem J        ISSN: 0264-6021            Impact factor:   3.857


  37 in total

1.  DELETION OF THYMIDINE KINASE ACTIVITY FROM L CELLS RESISTANT TO BROMODEOXYURIDINE.

Authors:  S KIT; D R DUBBS; L J PIEKARSKI; T C HSU
Journal:  Exp Cell Res       Date:  1963-08       Impact factor: 3.905

2.  Transformation of mammalian cells with genes from procaryotes and eucaryotes.

Authors:  M Wigler; R Sweet; G K Sim; B Wold; A Pellicer; E Lacy; T Maniatis; S Silverstein; R Axel
Journal:  Cell       Date:  1979-04       Impact factor: 41.582

3.  Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids.

Authors:  A J Berk; P A Sharp
Journal:  Cell       Date:  1977-11       Impact factor: 41.582

4.  Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I.

Authors:  P W Rigby; M Dieckmann; C Rhodes; P Berg
Journal:  J Mol Biol       Date:  1977-06-15       Impact factor: 5.469

5.  Mechanisms of regulating tubulin synthesis in cultured mammalian cells.

Authors:  A Ben-Ze'ev; S R Farmer; S Penman
Journal:  Cell       Date:  1979-06       Impact factor: 41.582

Review 6.  Molecular biology and genetics of tubulin.

Authors:  D W Cleveland; K F Sullivan
Journal:  Annu Rev Biochem       Date:  1985       Impact factor: 23.643

7.  Nucleotide and corresponding amino acid sequences encoded by alpha and beta tubulin mRNAs.

Authors:  P Valenzuela; M Quiroga; J Zaldivar; W J Rutter; M W Kirschner; D W Cleveland
Journal:  Nature       Date:  1981-02-19       Impact factor: 49.962

8.  Reconstruction of appropriate tubulin and actin gene regulation after transient transfection of cloned beta-tubulin and beta-actin genes.

Authors:  J T Lau; M F Pittenger; D W Cleveland
Journal:  Mol Cell Biol       Date:  1985-07       Impact factor: 4.272

9.  Retention of autoregulatory control of tubulin synthesis in cytoplasts: demonstration of a cytoplasmic mechanism that regulates the level of tubulin expression.

Authors:  M F Pittenger; D W Cleveland
Journal:  J Cell Biol       Date:  1985-11       Impact factor: 10.539

10.  Cell motility by labile association of molecules. The nature of mitotic spindle fibers and their role in chromosome movement.

Authors:  S Inoué; H Sato
Journal:  J Gen Physiol       Date:  1967-07       Impact factor: 4.086

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  4 in total

1.  An oocyte-expressed alpha-tubulin gene in Xenopus laevis; sequences required for the initiation of transcription.

Authors:  K M Middleton; G T Morgan
Journal:  Nucleic Acids Res       Date:  1989-07-11       Impact factor: 16.971

2.  The 5' splice site: phylogenetic evolution and variable geometry of association with U1RNA.

Authors:  M Jacob; H Gallinaro
Journal:  Nucleic Acids Res       Date:  1989-03-25       Impact factor: 16.971

3.  Premature termination of transcription can be induced on an injected alpha-tubulin gene in Xenopus oocytes.

Authors:  K M Middleton; G T Morgan
Journal:  Mol Cell Biol       Date:  1990-02       Impact factor: 4.272

4.  Alternative 3' processing of Xenopus alpha-tubulin mRNAs; efficient use of a CAUAAA polyadenylation signal.

Authors:  K G Rabbitts; G T Morgan
Journal:  Nucleic Acids Res       Date:  1992-06-25       Impact factor: 16.971

  4 in total

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