Literature DB >> 33419177

Lung Ultrasound Is Often, but Not Always, Normal in Healthy Subjects: Considerations for COVID-19 Pandemic.

Alberto Raiteri1, Margherita Alvisi1, Ilaria Serio1,2, Federico Stefanini2, Francesco Tovoli1,2, Fabio Piscaglia1,2.   

Abstract

BACKGROUND: Lung ultrasound (LU) is becoming an increasingly important diagnostic tool in detecting lung involvement in Corona Virus Disease 2019 (COVID-19). The aim of this study was to ascertain the likelihood of finding LU abnormalities; mimicking lung involvement; in COVID-19 negative healthy individuals.
METHODS: We performed LU on 265 healthcare workers; not presenting COVID-19 major symptoms and in good health; during the course of a serological screening program for COVID-19 in our General Hospital. LU results were reported as total Lung Ultrasound Score (LUS) using a 12-zone method of reporting.
RESULTS: 250/265 subjects were included in the COVID-19 negative group. LU was not completely normal (LUS ≠ 0) in 65/250 COVID-19 negative subjects (26%) and in 12/15 (80%) poorly symptomatic COVID-19 positive subjects; with a multifocal pattern in 12.7% vs. 66.7% of cases respectively. Age and COVID-19 positivity were independent predictors of total LUS. A total LUS ≥ 2 had a sensitivity of 66.67% and a specificity of 85.60% in detecting COVID-19 positivity.
CONCLUSIONS: A slightly altered LU can be quite frequent in healthy COVID-19 negative subjects. LU can have a role in confirming but not screening COVID-19 poorly symptomatic cases.

Entities:  

Keywords:  COVID-19; healthy individuals; interstitial syndrome; lung ultrasound; point-of-care ultrasound; subpleural consolidations

Year:  2021        PMID: 33419177      PMCID: PMC7825526          DOI: 10.3390/diagnostics11010082

Source DB:  PubMed          Journal:  Diagnostics (Basel)        ISSN: 2075-4418


  10 in total

Review 1.  Ultrasound for "lung monitoring" of ventilated patients.

Authors:  Belaïd Bouhemad; Silvia Mongodi; Gabriele Via; Isabelle Rouquette
Journal:  Anesthesiology       Date:  2015-02       Impact factor: 7.892

2.  Benefits, Open questions and Challenges of the use of Ultrasound in the COVID-19 pandemic era. The views of a panel of worldwide international experts.

Authors:  Fabio Piscaglia; Federico Stefanini; Vito Cantisani; Paul S Sidhu; Richard Barr; Annalisa Berzigotti; Maria Cristina Chammas; Jean-Michel Correas; Christoph Frank Dietrich; Steven Feinstein; Pintong Huang; Christian Jenssen; Yuko Kono; Masatoshi Kudo; Ping Liang; Andrej Lyshchik; Christian Nolsøe; Xyaoyan Xie; Francesco Tovoli
Journal:  Ultraschall Med       Date:  2020-04-15       Impact factor: 6.548

3.  Interpreting Diagnostic Tests for SARS-CoV-2.

Authors:  Nandini Sethuraman; Sundararaj Stanleyraj Jeremiah; Akihide Ryo
Journal:  JAMA       Date:  2020-06-09       Impact factor: 56.272

Review 4.  Ultrasound of the pleurae and lungs.

Authors:  Christoph F Dietrich; Gebhard Mathis; Xin-Wu Cui; Andre Ignee; Michael Hocke; Tim O Hirche
Journal:  Ultrasound Med Biol       Date:  2015-02       Impact factor: 2.998

5.  Lung ultrasound in the frontline diagnosis of COVID-19 infection.

Authors:  Yale Tung-Chen; Maria Angélica Rivera-Núñez; Ana María Martínez-Virto
Journal:  Med Clin (Barc)       Date:  2020-06-12       Impact factor: 1.725

6.  Lung Ultrasound in COVID-19 Pneumonia: Correlations with Chest CT on Hospital admission.

Authors:  Antonio Nouvenne; Marco Davìd Zani; Gianluca Milanese; Alberto Parise; Marco Baciarello; Elena Giovanna Bignami; Anna Odone; Nicola Sverzellati; Tiziana Meschi; Andrea Ticinesi
Journal:  Respiration       Date:  2020-06-22       Impact factor: 3.580

7.  Clinical Characteristics of Coronavirus Disease 2019 in China.

Authors:  Wei-Jie Guan; Zheng-Yi Ni; Yu Hu; Wen-Hua Liang; Chun-Quan Ou; Jian-Xing He; Lei Liu; Hong Shan; Chun-Liang Lei; David S C Hui; Bin Du; Lan-Juan Li; Guang Zeng; Kwok-Yung Yuen; Ru-Chong Chen; Chun-Li Tang; Tao Wang; Ping-Yan Chen; Jie Xiang; Shi-Yue Li; Jin-Lin Wang; Zi-Jing Liang; Yi-Xiang Peng; Li Wei; Yong Liu; Ya-Hua Hu; Peng Peng; Jian-Ming Wang; Ji-Yang Liu; Zhong Chen; Gang Li; Zhi-Jian Zheng; Shao-Qin Qiu; Jie Luo; Chang-Jiang Ye; Shao-Yong Zhu; Nan-Shan Zhong
Journal:  N Engl J Med       Date:  2020-02-28       Impact factor: 91.245

8.  Why, when, and how to use lung ultrasound during the COVID-19 pandemic: enthusiasm and caution.

Authors:  Luna Gargani; Hatem Soliman-Aboumarie; Giovanni Volpicelli; Francesco Corradi; Maria Concetta Pastore; Matteo Cameli
Journal:  Eur Heart J Cardiovasc Imaging       Date:  2020-09-01       Impact factor: 6.875

9.  Frequency and Distribution of Chest Radiographic Findings in Patients Positive for COVID-19.

Authors:  Ho Yuen Frank Wong; Hiu Yin Sonia Lam; Ambrose Ho-Tung Fong; Siu Ting Leung; Thomas Wing-Yan Chin; Christine Shing Yen Lo; Macy Mei-Sze Lui; Jonan Chun Yin Lee; Keith Wan-Hang Chiu; Tom Wai-Hin Chung; Elaine Yuen Phin Lee; Eric Yuk Fai Wan; Ivan Fan Ngai Hung; Tina Poy Wing Lam; Michael D Kuo; Ming-Yen Ng
Journal:  Radiology       Date:  2020-03-27       Impact factor: 11.105

Review 10.  Operational Strategies to Prevent Coronavirus Disease 2019 (COVID-19) Spread in Radiology: Experience From a Singapore Radiology Department After Severe Acute Respiratory Syndrome.

Authors:  Yonggeng Goh; Wynne Chua; Joseph K T Lee; Bertrand Wei Leng Ang; Chong Ri Liang; Choon Ann Tan; Denise Ai Wen Choong; Hui Xiang Hoon; Michael Kah Leong Ong; Swee Tian Quek
Journal:  J Am Coll Radiol       Date:  2020-04-03       Impact factor: 5.532

  10 in total
  2 in total

1.  Pulmonary Function and Psychological Burden Three Months after COVID-19: Proposal of a Comprehensive Multidimensional Assessment Protocol.

Authors:  Guido Vagheggini; Francesca Marzetti; Mario Miniati; Lorenzo Bernardeschi; Mario Miccoli; Giulia Boni Brivio; Simone Meini; Eugenia Panait; Elena Cini; Angelo Gemignani
Journal:  Healthcare (Basel)       Date:  2022-03-25

Review 2.  Lung Ultrasound: A Diagnostic Leading Tool for SARS-CoV-2 Pneumonia: A Narrative Review.

Authors:  Luigi Maggi; Anna Maria Biava; Silvia Fiorelli; Flaminia Coluzzi; Alberto Ricci; Monica Rocco
Journal:  Diagnostics (Basel)       Date:  2021-12-17
  2 in total

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