Literature DB >> 33419159

SARS-CoV-2 Testing for Asymptomatic Patients with Cancer Prior and during Treatment: A Single Centre Experience.

Nicholas Meti1, Houman Tahmasebi1, Angela Leahey2, Angela Boudreau2, Alia Thawer3, Janice Stewart2, Paige Reason2, Kirsty Albright2, Jerome A Leis1,4, Kevin Katz1,5, Matthew C Cheung1,2, Simron Singh1,2.   

Abstract

Patients with cancer are more vulnerable to severe COVID-19. As a result, routine SARS-CoV-2 testing of asymptomatic patients with cancer is recommended prior to treatment. However, there is limited evidence of its clinical usefulness. The objective of this study is to evaluate the value of routine testing of asymptomatic patients with cancer. Asymptomatic patients with cancer attending Odette Cancer Centre (Toronto, ON, Canada) were tested for SARS-CoV-2 prior to and during treatment cycles. Results were compared to positivity rates of SARS-CoV-2 locally and provincially. All 890 asymptomatic patients tested negative. Positivity rates in the province were 1.5%, in hospital were 1.0%, and among OCC's symptomatic cancer patients were 0% over the study period. Given our findings and the low SARS-CoV-2 community positivity rates, we recommend a dynamic testing model of asymptomatic patients that triggers testing during increasing community positivity rates of SARS-CoV-2.

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Year:  2021        PMID: 33419159      PMCID: PMC7903264          DOI: 10.3390/curroncol28010032

Source DB:  PubMed          Journal:  Curr Oncol        ISSN: 1198-0052            Impact factor:   3.677


  8 in total

1.  Systematic Assessment of Multiple Routine and Near Real-Time Indicators to Classify the Severity of Influenza Seasons and Pandemics in the United States, 2003-2004 Through 2015-2016.

Authors:  Matthew Biggerstaff; Krista Kniss; Daniel B Jernigan; Lynnette Brammer; Joseph Bresee; Shikha Garg; Erin Burns; Carrie Reed
Journal:  Am J Epidemiol       Date:  2018-05-01       Impact factor: 4.897

2.  Prevalence of respiratory viruses among adults, by season, age, respiratory tract region and type of medical unit in Paris, France, from 2011 to 2016.

Authors:  Benoit Visseaux; Charles Burdet; Guillaume Voiriot; François-Xavier Lescure; Taous Chougar; Olivier Brugière; Bruno Crestani; Enrique Casalino; Charlotte Charpentier; Diane Descamps; Jean-François Timsit; Yazdan Yazdanpanah; Nadhira Houhou-Fidouh
Journal:  PLoS One       Date:  2017-07-14       Impact factor: 3.240

3.  Patients with Cancer Appear More Vulnerable to SARS-CoV-2: A Multicenter Study during the COVID-19 Outbreak.

Authors:  Mengyuan Dai; Dianbo Liu; Miao Liu; Fuxiang Zhou; Guiling Li; Zhen Chen; Zhian Zhang; Hua You; Meng Wu; Qichao Zheng; Yong Xiong; Huihua Xiong; Chun Wang; Changchun Chen; Fei Xiong; Yan Zhang; Yaqin Peng; Siping Ge; Bo Zhen; Tingting Yu; Ling Wang; Hua Wang; Yu Liu; Yeshan Chen; Junhua Mei; Xiaojia Gao; Zhuyan Li; Lijuan Gan; Can He; Zhen Li; Yuying Shi; Yuwen Qi; Jing Yang; Daniel G Tenen; Li Chai; Lorelei A Mucci; Mauricio Santillana; Hongbing Cai
Journal:  Cancer Discov       Date:  2020-04-28       Impact factor: 39.397

4.  Screening for COVID-19 in Asymptomatic Patients With Cancer in a Hospital in the United Arab Emirates.

Authors:  Humaid O Al-Shamsi; Eric A Coomes; Sadir Alrawi
Journal:  JAMA Oncol       Date:  2020-10-01       Impact factor: 31.777

5.  Projecting the transmission dynamics of SARS-CoV-2 through the postpandemic period.

Authors:  Stephen M Kissler; Christine Tedijanto; Yonatan H Grad; Marc Lipsitch; Edward Goldstein
Journal:  Science       Date:  2020-04-14       Impact factor: 47.728

Review 6.  A Practical Approach to the Management of Cancer Patients During the Novel Coronavirus Disease 2019 (COVID-19) Pandemic: An International Collaborative Group.

Authors:  Humaid O Al-Shamsi; Waleed Alhazzani; Ahmad Alhuraiji; Eric A Coomes; Roy F Chemaly; Meshari Almuhanna; Robert A Wolff; Nuhad K Ibrahim; Melvin L K Chua; Sebastien J Hotte; Brandon M Meyers; Tarek Elfiki; Giuseppe Curigliano; Cathy Eng; Axel Grothey; Conghua Xie
Journal:  Oncologist       Date:  2020-04-27

7.  A War on Two Fronts: Cancer Care in the Time of COVID-19.

Authors:  Alexander Kutikov; David S Weinberg; Martin J Edelman; Eric M Horwitz; Robert G Uzzo; Richard I Fisher
Journal:  Ann Intern Med       Date:  2020-03-27       Impact factor: 25.391

8.  Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China.

Authors:  Wenhua Liang; Weijie Guan; Ruchong Chen; Wei Wang; Jianfu Li; Ke Xu; Caichen Li; Qing Ai; Weixiang Lu; Hengrui Liang; Shiyue Li; Jianxing He
Journal:  Lancet Oncol       Date:  2020-02-14       Impact factor: 41.316

  8 in total
  4 in total

1.  Systematic SARS-CoV-2-testing for asymptomatic cancer patients treated at a public healthcare tertiary centre in Brazil.

Authors:  Aline F Fares; Luiza A Fadul; Barbara Benetton; Mauricio L Nogueira; Marcia Lanza; Daniel V Araújo
Journal:  Ecancermedicalscience       Date:  2021-07-26

2.  Risk stratification by anamnesis increases SARS-CoV-2 test efficiency in cancer patients.

Authors:  Christian Cornelius Arnold; Jens von der Grün; Mark Christoph Brekner; Jörg Licher; Emmanouil Fokas; Claus Rödel; Maximilian Fleischmann
Journal:  Strahlenther Onkol       Date:  2021-10-07       Impact factor: 3.621

3.  Natural immunity to SARS-CoV-2 and breakthrough infections in vaccinated and unvaccinated patients with cancer.

Authors:  Alessio Cortellini; Juan Aguilar-Company; Ramon Salazar; Mark Bower; Ailsa Sita-Lumsden; Andrea Plaja; Alvin J X Lee; Alexia Bertuzzi; Carlo Tondini; Nikolaos Diamantis; Clara Martinez-Vila; Aleix Prat; Eleanor Apthorp; Alessandra Gennari; David J Pinato
Journal:  Br J Cancer       Date:  2022-08-22       Impact factor: 9.075

4.  IL4I1 binds to TMPRSS13 and competes with SARS-CoV-2 spike.

Authors:  Jérôme Gatineau; Charlotte Nidercorne; Aurélie Dupont; Marie-Line Puiffe; José L Cohen; Valérie Molinier-Frenkel; Florence Niedergang; Flavia Castellano
Journal:  Front Immunol       Date:  2022-09-05       Impact factor: 8.786

  4 in total

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