| Literature DB >> 33415828 |
Katherukamem Rajukumar1, Dhanapal Senthilkumar1, Govindarajulu Venkatesh1, Fateh Singh1, Vishnu P Patil1, Subbiah Kombiah1, Chakradhar Tosh1, Chandan K Dubey1, Arnab Sen2, Nagendra N Barman3, Amitav Chakravarty4, Biswajit Dutta3, Seema R Pegu5, Arpita Bharali3, Vijendra P Singh1.
Abstract
African swine fever (ASF) is the most dreaded disease of pigs, which can cause mortality of up to 100%. Following disease outbreaks with high mortality in pigs in two states of north-east India, namely Arunachal Pradesh and Assam in early 2020, we confirmed the first occurrence of African swine fever (ASF) in domestic pigs in India by real-time PCR, virus isolation and nucleotide sequencing. Genetic analyses in three independent genomic regions (B646L gene encoding the p72 protein, E183L gene encoding the p54 protein and the central variable region (CVR) of B602L gene) showed that the Indian ASF viruses are similar to the post-2007-p72-genotype II viruses reported from Asia and Europe, suggesting the transboundary expansion of ongoing ASF outbreaks in the region.Entities:
Keywords: ASF; African swine fever; African swine fever virus; CVR; India; genotype II; p54; p72; phylogenetic analysis; pigs
Year: 2021 PMID： 33415828 DOI： 10.1111/tbed.13986
Source DB: PubMed Journal: Transbound Emerg Dis ISSN： 1865-1674 Impact factor: 5.005