Literature DB >> 33415734

Acute aortic dissection type A: Impact of aortic specialists on short and long term outcomes.

Habib Khan1, Azhar Hussain1, Sanjay Chaubey1, Mohamed Sameh1, Inga Salter1, Ranjit Deshpande1, Max Baghai1, Olaf Wendler1.   

Abstract

OBJECTIVES: Acute aortic dissection type-A (AADA) is a life threatening condition which requires emergency surgery. Surgery is usually performed by cardiac surgeons with various levels of aortic surgical experience. We compared the short-term perioperative outcome and long-term survival of patients operated by specialist aortic surgeons (SASs)and those who were operated by surgeons without specialist expertise.
METHODS: A single center retrospective review of 232 patients who underwent acute surgery for AADA was conducted between 2005 and 2020. The cohort was divided into those operated on by SASs (Group A, n = 186) and those operated on by nonaortic surgeons (Group B, n = 46). Statistical comparison was done using regression modelling and groups were propensity matched. Kaplan-Meier comparison was undertaken using STATA14.
RESULTS: Of 232 patients, 186 were operated on by an aortic specialist and 46 were operated by a nonaortic specialist. Overall 30-day mortality was 10% in Group A compared to 26.0% in Group B (unadjusted: p = .01, multivariate: p = .02, and propensity matched p = .05). Long-term mortality at 14 years was 26% in Group A compared to 52.0% in Group B (unadjusted: p = .001, multivariate: p = .001, and propensity matched: p = .01). Aortic surgeons performed a significantly higher number of aortic root procedures (43.0% vs. 17.3%, p = .001). The cross-clamp time and bypass time was significantly shorter in Group A patients (89 vs. 105 min, p < .01 and 153 vs. 185, p = < .001). Postoperative requirement for renal filtration was (19% vs. 37%, unadjusted p = .01, multivariate p = .03 and propensity matched p = .04). Although postoperative bleeding was less in Group A (4.0% vs. 11.0%, unadjusted p = .05) after propensity matching it was not statistically significant.
CONCLUSIONS: In patients with AADA, surgery performed by aortic specialist's results in improved outcomes. Aortic specialists replaced more of dissected aorta, resulting in an increased number of complex procedures, which may explain improved long-term survival after AADA in this cohort. This study adds further support in establishing a specialist aortic surgical service in cardiac centers.
© 2021 Wiley Periodicals LLC.

Entities:  

Keywords:  aorta; aortic dissection; aortic surgery; dissection

Mesh:

Year:  2021        PMID: 33415734     DOI: 10.1111/jocs.15292

Source DB:  PubMed          Journal:  J Card Surg        ISSN: 0886-0440            Impact factor:   1.620


  3 in total

1.  Th1, Th2, and Th17 cells are dysregulated, but only Th17 cells relate to C-reactive protein, D-dimer, and mortality risk in Stanford type A aortic dissection patients.

Authors:  Mowei Song; Li Deng; Hongtao Shen; Guofu Zhang; Hang Shi; Erjun Zhu; Qingping Xia; Hongguang Han
Journal:  J Clin Lab Anal       Date:  2022-05-06       Impact factor: 3.124

2.  Association of dissected ascending aorta diameter with preoperative adverse events in patients with acute type A aortic dissection.

Authors:  George Samanidis; Meletios Kanakis; Charalampos Georgiou; Konstantinos Perreas
Journal:  World J Cardiol       Date:  2022-04-26

3.  Early Results of a Novel Hybrid Prosthesis for Treatment of Acute Aortic Dissection Type A With Distal Anastomosis Line Beyond Aortic Arch Zone Zero.

Authors:  Arash Mehdiani; Yukiharu Sugimura; Louise Wollgarten; Moritz Benjamin Immohr; Sebastian Bauer; Hubert Schelzig; Markus Udo Wagenhäuser; Gerald Antoch; Artur Lichtenberg; Payam Akhyari
Journal:  Front Cardiovasc Med       Date:  2022-07-14
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.