Literature DB >> 33415150

Antiepileptic Drug Management in Acute Ischemic Stroke: Are Vascular Neurologists Utilizing Electroencephalograms? An Observational Cohort Study.

Rahul Rao1, Dominique J Monlezun1, Tara Kimbrough1, Brian J Burkett1, Alyana Samai1, Sheryl Martin-Schild1.   

Abstract

INTRODUCTION: This study examines the utility of electroencephalography (EEG) in clinical decision making in acute ischemic stroke (AIS) patients in regards to the prescription of antiseizure medications.
METHODS: Patients were grouped as having positive EEG (+) for epileptiform activity or negative EEG (-). These studies were no more than 30 minutes in length. Patients' charts were retrospectively reviewed for antiepileptic drug (AED) use before, during, and on discharge from AIS hospitalization.
RESULTS: Of the 509 patients meeting inclusion criteria, 24 (4.7%) had a positive EEG. Patients did not significantly differ with respect to any demographic or baseline characteristics with the exception of prior history of seizure. In the EEG- group, AEDs were discontinued in only 3.5% of patients. In the EEG+ group, only 37.5% of patients had an initiation or change to their AED regimen within 36 hours of the study. 62.5% of the EEG+ group had a cortical stroke. Significance. Our results indicate that vascular neurologists are not using spot EEGs to routinely guide inpatient AED management. EEGs may have greater utility in those with a prior history of seizures and cortical strokes. Longer or continuous EEG monitoring may have better utility in the AIS population if there is clinical suspicion of seizure.
Copyright © 2020 Rahul Rao et al.

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Year:  2020        PMID: 33415150      PMCID: PMC7769647          DOI: 10.1155/2020/6250531

Source DB:  PubMed          Journal:  Biomed Res Int            Impact factor:   3.411


  21 in total

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Journal:  Brain Topogr       Date:  2010-06-24       Impact factor: 3.020

Review 6.  Incidence and management of seizures after ischemic stroke: Systematic review and meta-analysis.

Authors:  Jeffrey Z Wang; Manav V Vyas; Gustavo Saposnik; Jorge G Burneo
Journal:  Neurology       Date:  2017-08-23       Impact factor: 9.910

7.  How seizure detection by continuous electroencephalographic monitoring affects the prescribing of antiepileptic medications.

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8.  Complications of acute stroke and the occurrence of early seizures.

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Journal:  Cerebrovasc Dis       Date:  2013-05-31       Impact factor: 2.762

9.  Anticonvulsant use and outcomes after intracerebral hemorrhage.

Authors:  Andrew M Naidech; Rajeev K Garg; Storm Liebling; Kimberly Levasseur; Micheal P Macken; Stephan U Schuele; H Hunt Batjer
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10.  Early EEG predicts poststroke epilepsy.

Authors:  Carla Bentes; Hugo Martins; Ana Rita Peralta; Carlos Morgado; Carlos Casimiro; Ana Catarina Franco; Ana Catarina Fonseca; Ruth Geraldes; Patrícia Canhão; Teresa Pinho E Melo; Teresa Paiva; José M Ferro
Journal:  Epilepsia Open       Date:  2018-03-07
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