Literature DB >> 33415091

Real-Time Estimation of R t for Supporting Public-Health Policies Against COVID-19.

Sebastián Contreras1, H Andrés Villavicencio1, David Medina-Ortiz1,2,3, Claudia P Saavedra4, Álvaro Olivera-Nappa1,2.   

Abstract

In the absence of a consensus protocol to slow down the spread of SARS-CoV-2, policymakers need real-time indicators to support decisions in public health matters. The Effective Reproduction Number (R t ) represents the number of secondary infections generated per each case and can be dramatically modified by applying effective interventions. However, current methodologies to calculate R t from data remain somewhat cumbersome, thus raising a barrier between its timely calculation and application by policymakers. In this work, we provide a simple mathematical formulation for obtaining the effective reproduction number in real-time using only and directly daily official case reports, obtained by modifying the equations describing the viral spread. We numerically explore the accuracy and limitations of the proposed methodology, which was demonstrated to provide accurate, timely, and intuitive results. We illustrate the use of our methodology to study the evolution of the pandemic in different iconic countries, and to assess the efficacy and promptness of different public health interventions.
Copyright © 2020 Contreras, Villavicencio, Medina-Ortiz, Saavedra and Olivera-Nappa.

Entities:  

Keywords:  COVID-19; SARS-CoV-2; effective reproduction number Rt; epidemiologic modeling; public-health policies

Mesh:

Year:  2020        PMID: 33415091      PMCID: PMC7783316          DOI: 10.3389/fpubh.2020.556689

Source DB:  PubMed          Journal:  Front Public Health        ISSN: 2296-2565


  10 in total

1.  A brief history of R0 and a recipe for its calculation.

Authors:  J A P Heesterbeek
Journal:  Acta Biotheor       Date:  2002       Impact factor: 1.774

2.  A note on generation times in epidemic models.

Authors:  Ake Svensson
Journal:  Math Biosci       Date:  2006-11-09       Impact factor: 2.144

3.  Estimating initial epidemic growth rates.

Authors:  Junling Ma; Jonathan Dushoff; Benjamin M Bolker; David J D Earn
Journal:  Bull Math Biol       Date:  2013-11-23       Impact factor: 1.758

4.  Theory versus data: how to calculate R0?

Authors:  Romulus Breban; Raffaele Vardavas; Sally Blower
Journal:  PLoS One       Date:  2007-03-14       Impact factor: 3.240

5.  Complexity of the Basic Reproduction Number (R0).

Authors:  Paul L Delamater; Erica J Street; Timothy F Leslie; Y Tony Yang; Kathryn H Jacobsen
Journal:  Emerg Infect Dis       Date:  2019-01       Impact factor: 6.883

6.  Transmissibility of 1918 pandemic influenza.

Authors:  Christina E Mills; James M Robins; Marc Lipsitch
Journal:  Nature       Date:  2004-12-16       Impact factor: 49.962

7.  A multi-group SEIRA model for the spread of COVID-19 among heterogeneous populations.

Authors:  Sebastián Contreras; H Andrés Villavicencio; David Medina-Ortiz; Juan Pablo Biron-Lattes; Álvaro Olivera-Nappa
Journal:  Chaos Solitons Fractals       Date:  2020-05-25       Impact factor: 5.944

8.  Statistically-based methodology for revealing real contagion trends and correcting delay-induced errors in the assessment of COVID-19 pandemic.

Authors:  Sebastián Contreras; Juan Pablo Biron-Lattes; H Andrés Villavicencio; David Medina-Ortiz; Nyna Llanovarced-Kawles; Álvaro Olivera-Nappa
Journal:  Chaos Solitons Fractals       Date:  2020-07-03       Impact factor: 9.922

9.  Modified SEIR and AI prediction of the epidemics trend of COVID-19 in China under public health interventions.

Authors:  Zifeng Yang; Zhiqi Zeng; Ke Wang; Sook-San Wong; Wenhua Liang; Mark Zanin; Peng Liu; Xudong Cao; Zhongqiang Gao; Zhitong Mai; Jingyi Liang; Xiaoqing Liu; Shiyue Li; Yimin Li; Feng Ye; Weijie Guan; Yifan Yang; Fei Li; Shengmei Luo; Yuqi Xie; Bin Liu; Zhoulang Wang; Shaobo Zhang; Yaonan Wang; Nanshan Zhong; Jianxing He
Journal:  J Thorac Dis       Date:  2020-03       Impact factor: 3.005

10.  Assessing the progression of the COVID-19 pandemic in Canada using testing data and time-dependent reproduction numbers.

Authors:  Rojiemiahd Edjoc; Nicole Atchessi; Amanda Lien; Ben A Smith; Imran Gabrani-Juma; Christine Abalos; Marianne Heisz
Journal:  Can J Public Health       Date:  2020-10-22
  10 in total
  5 in total

1.  Statistically-based methodology for revealing real contagion trends and correcting delay-induced errors in the assessment of COVID-19 pandemic.

Authors:  Sebastián Contreras; Juan Pablo Biron-Lattes; H Andrés Villavicencio; David Medina-Ortiz; Nyna Llanovarced-Kawles; Álvaro Olivera-Nappa
Journal:  Chaos Solitons Fractals       Date:  2020-07-03       Impact factor: 9.922

2.  Evaluating alternative hypotheses to explain the downward trend in the indices of the COVID-19 pandemic death rate.

Authors:  Sonali Shinde; Pratima Ranade; Milind Watve
Journal:  PeerJ       Date:  2021-04-20       Impact factor: 2.984

3.  Analysis of Key Factors of a SARS-CoV-2 Vaccination Program: A Mathematical Modeling Approach.

Authors:  David Martínez-Rodríguez; Gilberto Gonzalez-Parra; Rafael-J Villanueva
Journal:  Epidemiologia (Basel)       Date:  2021-04-01

4.  On the heterogeneous spread of COVID-19 in Chile.

Authors:  Danton Freire-Flores; Nyna Llanovarced-Kawles; Anamaria Sanchez-Daza; Álvaro Olivera-Nappa
Journal:  Chaos Solitons Fractals       Date:  2021-06-12       Impact factor: 5.944

5.  Analysis of Delayed Vaccination Regimens: A Mathematical Modeling Approach.

Authors:  Gilberto Gonzalez-Parra
Journal:  Epidemiologia (Basel)       Date:  2021-07-20
  5 in total

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