Koichi Tamura1, Kenji Matsuda1, Tetsuya Horiuchi2, Kohei Noguchi3, Tsukasa Hotta4, Katsunari Takifuji5, Makoto Iwahashi6, Hiromitsu Iwamoto1, Yuki Mizumoto1, Hiroki Yamaue7. 1. Second Department of Surgery, School of Medicine, Wakayama Medical University, Wakayama, Japan. 2. Department of Surgery, National Hospital Organization Osaka Minami Medical Center, Osaka, Japan. 3. Department of Surgery and Endoscopic Surgery, Izumiotsu Municipal Hospital, Osaka, Japan. 4. Department of Surgery, National Hospital Organization Minami Wakayama Medical Center, Wakayama, Japan. 5. Department of Surgery, Saiseikai Arida Hospital, Wakayama, Japan. 6. Department of Surgery, Wakayama Rosai Hospital, Wakayama, Japan. 7. Second Department of Surgery, School of Medicine, Wakayama Medical University, Wakayama, Japan. Electronic address: yamaue-h@wakayama-med.ac.jp.
Abstract
BACKGROUND: In rectal cancer surgery, insertion of transanal tube has been shown to have efficacy to prevent anastomotic leakage. This randomized controlled study aims to clarify the incidence of anastomotic leakage with or without transanal tube in patients with rectal cancer. METHODS:Patients who underwent elective low anterior resection were randomly allocated to either have transanal tube insertion or not for five days after surgery. We examined the incidence of anastomotic leakage, postoperative 30-day morbidity and mortality. RESULTS:157 patients were randomized to the transanal tube group or the no-transanal tube group. Symptomatic anastomotic leakage occurred in six patients (7.6%) of the former group and eight patients (10.3%) in the latter group, without significant difference (p = 0.559). There was also no significant difference in morbidity between groups (p = 0.633) and no mortality was detected. CONCLUSIONS:Transanal tube insertion had no significant benefit towards prevention of anastomotic leakage in rectal cancer surgery.
RCT Entities:
BACKGROUND: In rectal cancer surgery, insertion of transanal tube has been shown to have efficacy to prevent anastomotic leakage. This randomized controlled study aims to clarify the incidence of anastomotic leakage with or without transanal tube in patients with rectal cancer. METHODS:Patients who underwent elective low anterior resection were randomly allocated to either have transanal tube insertion or not for five days after surgery. We examined the incidence of anastomotic leakage, postoperative 30-day morbidity and mortality. RESULTS: 157 patients were randomized to the transanal tube group or the no-transanal tube group. Symptomatic anastomotic leakage occurred in six patients (7.6%) of the former group and eight patients (10.3%) in the latter group, without significant difference (p = 0.559). There was also no significant difference in morbidity between groups (p = 0.633) and no mortality was detected. CONCLUSIONS: Transanal tube insertion had no significant benefit towards prevention of anastomotic leakage in rectal cancer surgery.
Authors: Antonio Sciuto; Roberto Peltrini; Federica Andreoli; Andrea Gianmario Di Santo Albini; Maria Michela Di Nuzzo; Nello Pirozzi; Marcello Filotico; Federica Lauria; Giuseppe Boccia; Michele D'Ambra; Ruggero Lionetti; Carlo De Werra; Felice Pirozzi; Francesco Corcione Journal: J Clin Med Date: 2022-05-07 Impact factor: 4.964