Literature DB >> 3341382

Assessment of aneuploidy in the human female by using cytogenetics of IVF failures.

F Pellestor1, B Sèle.   

Abstract

The karyotype was determined for 201 unfertilized human oocytes recovered from 87 women participating in an in vitro fertilization program. Their mean age was 30.6 years (range 22-40 years). Thirteen oocytes did not exhibit the first polar body and were found to be in the first-metaphase stage. The remaining 188 eggs were assessed as mature and classified into two groups according to the supposed origin of fertilization failure. The overall incidence of aneuploidy was 18.6%. This rate was higher in the group of unexplained fertilization failure (22.5%) than in the group of fertilization failure due to sperm deficiency (10.2%). This may reflect a relationship between the genomic constitution of the oocyte and its fertilizability. On the other hand, no increase of aneuploidy was observed with maternal aging.

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Mesh：

Year:  1988        PMID： 3341382      PMCID： PMC1715262     

Source DB:  PubMed          Journal:  Am J Hum Genet        ISSN： 0002-9297            Impact factor:   11.025


  35 in total

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Journal:  Hum Genet       Date:  1986-12       Impact factor: 4.132

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Journal:  Pathol Biol (Paris)       Date:  1985-11

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Authors:  H Spielmann; C Krüger; M Stauber; R Vogel
Journal:  J In Vitro Fert Embryo Transf       Date:  1985-09

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Authors:  B Sele; F Pellestor
Journal:  J Gynecol Obstet Biol Reprod (Paris)       Date:  1985

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Authors:  H Wramsby; K Fredga; P Liedholm
Journal:  N Engl J Med       Date:  1987-01-15       Impact factor: 91.245

6.  Chromosomes of human sperm: variability among normal individuals.

Authors:  B Brandriff; L Gordon; L Ashworth; G Watchmaker; D Moore; A J Wyrobek; A V Carrano
Journal:  Hum Genet       Date:  1985       Impact factor: 4.132

7.  Cytogenetics of human sperm: meiotic segregation in two translocation carriers.

Authors:  B Brandriff; L Gordon; L K Ashworth; V Littman; G Watchmaker; A V Carrano
Journal:  Am J Hum Genet       Date:  1986-02       Impact factor: 11.025

8.  Chromosomal analysis of unfertilized human oocytes.

Authors:  R H Martin; M M Mahadevan; P J Taylor; K Hildebrand; L Long-Simpson; D Peterson; J Yamamoto; J Fleetham
Journal:  J Reprod Fertil       Date:  1986-11

9.  Maternal age-specific rates of numerical chromosome abnormalities with special reference to trisomy.

Authors:  T Hassold; D Chiu
Journal:  Hum Genet       Date:  1985       Impact factor: 4.132

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Authors:  R R Angell; A A Templeton; R J Aitken
Journal:  Hum Genet       Date:  1986-04       Impact factor: 4.132
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  13 in total

1.  Hormonal stimulation for in vitro fertilization: a comparison of fertilization rates and cytogenetic findings in unfertilized oocytes.

Authors:  P De Sutter; M Dhont; D Vandekerckhove
Journal:  J Assist Reprod Genet       Date:  1992-06       Impact factor: 3.412

2.  Direct segregation analysis of reciprocal translocations: a study of 283 sperm karyotypes from four carriers.

Authors:  F Pellestor; B Sèle; H Jalbert; P Jalbert
Journal:  Am J Hum Genet       Date:  1989-04       Impact factor: 11.025

3.  Factors associated with premature chromosome condensation (PCC) following in vitro fertilization.

Authors:  M I Tejada; M R Mendoza; B Corcóstegui; J A Benito
Journal:  J Assist Reprod Genet       Date:  1992-02       Impact factor: 3.412

4.  Chromosomal analysis of unfertilized oocytes and morphologically abnormal preimplantation embryos from an in vitro fertilization program.

Authors:  G Michaeli; M Fejgin; Y Ghetler; I Ben Nun; Y Beyth; A Amiel
Journal:  J In Vitro Fert Embryo Transf       Date:  1990-12

5.  Frequency and distribution of aneuploidy in human female gametes.

Authors:  F Pellestor
Journal:  Hum Genet       Date:  1991-01       Impact factor: 4.132

6.  Chromosome analysis of single- and multipronucleated human zygotes proceeded after the intracytoplasmic sperm injection procedure.

Authors:  E Macas; B Imthurn; M Roselli; P J Keller
Journal:  J Assist Reprod Genet       Date:  1996-04       Impact factor: 3.412

7.  Rapid chromosome detection in human gametes, zygotes, and preimplantation embryos using the PRINS technique.

Authors:  F Pellestor; A Girardet; G Lefort; B Andréo; J P Charlieu
Journal:  J Assist Reprod Genet       Date:  1996-09       Impact factor: 3.412

8.  The microtubular cytoskeleton and chromosomes of unfertilized human oocytes aged in vitro.

Authors:  U Eichenlaub-Ritter; A Stahl; J M Luciani
Journal:  Hum Genet       Date:  1988-11       Impact factor: 4.132

9.  A 45,X/46,XX/47,XXX female mosaic detected by cytogenetic analysis of unfertilized IVF oocytes.

Authors:  P De Sutter; M Dhont; E Merchiers; T Coetsier; M R Verschraegen-Spae; M Coppens
Journal:  J Assist Reprod Genet       Date:  1993-08       Impact factor: 3.412

10.  Cytogenetics of uncleaved oocytes and arrested zygotes in IVF programs.

Authors:  M Benkhalifa; Y Menezo; L Janny; J L Pouly; M B Qumsiyeh
Journal:  J Assist Reprod Genet       Date:  1996-02       Impact factor: 3.412
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