Silvia Caristia1, Margherita Ferranti2,3, Edira Skrami4, Elena Raffetti5, Daniela Pierannunzio6, Raffeele Palladino7, Flavia Carle8, Rodolfo Saracci9, Chiara Badaloni2, Francesco Barone-Adesi1,10, Valeria Belleudi2, Carla Ancona2. 1. Department of Translational Medicine, University Piemonte Orientale, Novara (Italy). 2. Department of Epidemiology, Lazio Regional Health Service, Local Health Unit 1, Rome (Italy). 3. Department of Woman and Child Health and Public Health, Public Health Area, University Polyclinic Foundation "A. Gemelli" IRCCS, Rome (Italy). 4. Centre of Epidemiology and Biostatistics, Università politecnica delle Marche, Ancona (Italy); e.skrami@staff.univpm.it. 5. Epidemiology and public health intervention research group (EPHIR), Department of Global Public Health, Karolinska Institutet, Solna (Sweden). 6. National centre of disease prevention and health promotion, Italian National Health Institute, Rome (Italy). 7. Department of Public Health, "Federico II" University, Naples (Italy). 8. Centre of Epidemiology and Biostatistics, Università politecnica delle Marche, Ancona (Italy). 9. former president International Epidemiological Association. 10. Research Center in Emergency and Disaster Medicine (CRIMEDIM), University Piemonte Orientale, Novara (Italy).
Abstract
OBJECTIVES: to describe and compare the effectiveness of national and local lockdowns in controlling the spread of COVID-19. METHODS: a rapid review of published and grey literature on COVID-19 pandemic was conducted following predefined eligibility criteria by searching electronic databases, repositories of pre-print articles, websites and databases of international health, and research related institutions and organisations. RESULTS: of 584 initially identified records up to 5 July 2020, 19 articles met the inclusion criteria and were included in the review. Most of the studies (No. 11) used the reproduction number (Rt) as a measure of effect and in all of them areduction of the estimated value at post-intervention period was found. The implementation of lockdown in 11 European countries was associated with an average 82% reduction of Rt, ranging from a posterior Rt of 0.44 (95%CI 0.26-0.61) for Norway to a posterior Rt of 0.82 (95%CI 0.73- 0.93) for Belgium. Changes in infection rates and transmission rates were estimated in 8 studies. Daily changes in infection rates ranged from -0.6% (Sweden) to -11.3% (Hubei and Guangdong provinces). Additionally, other studies reported a change in the trend of hospitalizations (Italy, Spain) and positive effects on the doubling time of cases (Hubei, China) after lockdown. CONCLUSIONS: results of this rapid review suggest a positive effect of the containment measures on the spread of COVID-19 pandemic, with a major effect in countries where lockdown started early and was more restrictive. Rigorous research is warranted to evaluate which approach is the most effective in each stage of the epidemic and in specific social contexts, in particular addressing if these approaches should be implemented on the whole population or target specific risk groups.
OBJECTIVES: to describe and compare the effectiveness of national and local lockdowns in controlling the spread of COVID-19. METHODS: a rapid review of published and grey literature on COVID-19 pandemic was conducted following predefined eligibility criteria by searching electronic databases, repositories of pre-print articles, websites and databases of international health, and research related institutions and organisations. RESULTS: of 584 initially identified records up to 5 July 2020, 19 articles met the inclusion criteria and were included in the review. Most of the studies (No. 11) used the reproduction number (Rt) as a measure of effect and in all of them areduction of the estimated value at post-intervention period was found. The implementation of lockdown in 11 European countries was associated with an average 82% reduction of Rt, ranging from a posterior Rt of 0.44 (95%CI 0.26-0.61) for Norway to a posterior Rt of 0.82 (95%CI 0.73- 0.93) for Belgium. Changes in infection rates and transmission rates were estimated in 8 studies. Daily changes in infection rates ranged from -0.6% (Sweden) to -11.3% (Hubei and Guangdong provinces). Additionally, other studies reported a change in the trend of hospitalizations (Italy, Spain) and positive effects on the doubling time of cases (Hubei, China) after lockdown. CONCLUSIONS: results of this rapid review suggest a positive effect of the containment measures on the spread of COVID-19 pandemic, with a major effect in countries where lockdown started early and was more restrictive. Rigorous research is warranted to evaluate which approach is the most effective in each stage of the epidemic and in specific social contexts, in particular addressing if these approaches should be implemented on the whole population or target specific risk groups.
Authors: Francisco Javier Candel; Jesús San-Román; Pablo Barreiro; Jesús Canora; Antonio Zapatero; Mar Carretero; Antonio Lastra; Francisco Javier Martínez-Peromingo Journal: Lancet Reg Health Eur Date: 2021-03-19
Authors: Z Y Sheng; M Li; R Yang; Y H Liu; X X Yin; J R Mao; Heidi E Brown; J An; H N Zhou; P G Wang Journal: Emerg Microbes Infect Date: 2022-12 Impact factor: 7.163
Authors: Rebecca Crowder; Donna Mae Geocaniga-Gaviola; Ronald Allan Fabella; Alexander Lim; Evanisa Lopez; Jillian L Kadota; Tania F Reza; Adithya Cattamanchi; Anna Marie Celina Garfin Journal: J Clin Tuberc Other Mycobact Dis Date: 2021-10-16
Authors: Raffaele Palladino; Daniele Ceriotti; Damiano De Ambrosi; Marta De Vito; Marco Farsoni; Giuseppina Seminara; Francesco Barone-Adesi Journal: Vaccines (Basel) Date: 2021-06-08