| Literature DB >> 33411176 |
Marco Ripa1, Stefania Chiappetta1, Barbara Castiglioni1, Eustachio Agricola2, Elena Busnardo3, Silvia Carletti4, Alessandro Castiglioni5, Michele De Bonis5, Giovanni La Canna2, Chiara Oltolini1, Ursola Pajoro3, Renée Pasciuta4, Chiara Tassan Din1, Paolo Scarpellini6.
Abstract
The purpose of this study was to evaluate the impact of surgical timing on survival in patients with left-sided infective endocarditis (IE). This was a retrospective study including 313 patients with left-sided IE between 2009 and 2017. Surgery was defined as urgent (US) or early (ES) if performed within 7 or 28 days, respectively. A multivariable Cox regression analysis including US and ES as time-dependent variables was performed to assess the impact on 1-year mortality. ES was associated with a better survival (aHR 0.349, 95% CI 0.135-0.902), as US (aHR 0.262, 95% CI 0.075-0.915). ES and US were associated with a better prognosis in patients with left-sided IE.Entities:
Keywords: Infective endocarditis; Surgery; Time-dependent; Timing
Year: 2021 PMID： 33411176 DOI： 10.1007/s10096-020-04133-x
Source DB: PubMed Journal: Eur J Clin Microbiol Infect Dis ISSN： 0934-9723 Impact factor: 3.267