Kamlesh Kaitholia1, Hirak Ranjan Dash1, Pankaj Shrivastava2, R K Kumawat3, Shivani Dixit1, Gyaneshwer Chaubey4. 1. DNA Fingerprinting Unit, State Forensic Science Laboratory, Sagar, Madhya Pradesh, 470001, India. 2. DNA Fingerprinting Unit, State Forensic Science Laboratory, Sagar, Madhya Pradesh, 470001, India. pankaj.shrivastava@rediffmail.com. 3. DNA Division, State Forensic Science Laboratory, Jaipur, Rajasthan, 302016, India. 4. Cytogenetics Laboratory, Dept. of Zoology, Banaras Hindu University, Varanasi, 221005, India.
Abstract
INTRODUCTION: Forensic characterization and genetic evaluation study in the 539 randomly selected unrelated adult healthy individuals belonging to the Central Indian population was undertaken. METHODS: The study was performed using a multiplex of 27 Y-STRs incoporated in Yfiler™ Plus multiplex kit. RESULTS: Out of 539 samples, 6 samples were observed for large deletion and tri-allelic patterns, which were removed from the analysis, and out of 533 samples, a total of 507 haplotypes were found, and out of these haplotypes, 482 unique haplotypes were found in this piece of work. The forensically important parameters, i.e., gene diversity (GD) and discrimination capacity (DC), were found to be 0.669 and 0.951, respectively, for the tested Y STR loci. The genetic data of this study will enrich the Y STR data bank and being used as a potential tool for forensic DNA and various genetic studies.
INTRODUCTION: Forensic characterization and genetic evaluation study in the 539 randomly selected unrelated adult healthy individuals belonging to the Central Indian population was undertaken. METHODS: The study was performed using a multiplex of 27 Y-STRs incoporated in Yfiler™ Plus multiplex kit. RESULTS: Out of 539 samples, 6 samples were observed for large deletion and tri-allelic patterns, which were removed from the analysis, and out of 533 samples, a total of 507 haplotypes were found, and out of these haplotypes, 482 unique haplotypes were found in this piece of work. The forensically important parameters, i.e., gene diversity (GD) and discrimination capacity (DC), were found to be 0.669 and 0.951, respectively, for the tested Y STR loci. The genetic data of this study will enrich the Y STR data bank and being used as a potential tool for forensic DNA and various genetic studies.
Entities:
Keywords:
Forensic; Haplotype; India; Madhya Pradesh; Population data; Y-STR