Literature DB >> 33406725

RAB11-Mediated Trafficking and Human Cancers: An Updated Review.

Elsi Ferro1,2, Carla Bosia1,2, Carlo C Campa1,2.   

Abstract

Many disorders block and subvert basic cellular processes in order to boost their progression. One protein family that is prone to be altered in human cancers is the small GTPase RAB11 family, the master regulator of vesicular trafficking. RAB11 isoforms function as membrane organizers connecting the transport of cargoes towards the plasma membrane with the assembly of autophagic precursors and the generation of cellular protrusions. These processes dramatically impact normal cell physiology and their alteration significantly affects the survival, progression and metastatization as well as the accumulation of toxic materials of cancer cells. In this review, we discuss biological mechanisms ensuring cargo recognition and sorting through a RAB11-dependent pathway, a prerequisite to understand the effect of RAB11 alterations in human cancers.

Entities:  

Keywords:  RAB11; RAB25; cancer; endosome; sorting

Year:  2021        PMID： 33406725      PMCID： PMC7823896          DOI： 10.3390/biology10010026

Source DB:  PubMed          Journal:  Biology (Basel)        ISSN： 2079-7737


  115 in total

1.  The Arp2/3 activator WASH controls the fission of endosomes through a large multiprotein complex.

Authors:  Emmanuel Derivery; Carla Sousa; Jérémie J Gautier; Bérangère Lombard; Damarys Loew; Alexis Gautreau
Journal:  Dev Cell       Date:  2009-11       Impact factor: 12.270

2.  Rab25 associates with alpha5beta1 integrin to promote invasive migration in 3D microenvironments.

Authors:  Patrick T Caswell; Heather J Spence; Maddy Parsons; Dominic P White; Katherine Clark; Kwai Wa Cheng; Gordon B Mills; Martin J Humphries; Anthea J Messent; Kurt I Anderson; Mary W McCaffrey; Bradford W Ozanne; Jim C Norman
Journal:  Dev Cell       Date:  2007-10       Impact factor: 12.270

Review 3.  Rab proteins and the compartmentalization of the endosomal system.

Authors:  Angela Wandinger-Ness; Marino Zerial
Journal:  Cold Spring Harb Perspect Biol       Date:  2014-10-23       Impact factor: 10.005

4.  Rab11 activity and PtdIns(3)P turnover removes recycling cargo from endosomes.

Authors:  Carlo Cosimo Campa; Jean Piero Margaria; Abhishek Derle; Marco Del Giudice; Emilio Hirsch; Maria Chiara De Santis; Luca Gozzelino; Francesca Copperi; Carla Bosia
Journal:  Nat Chem Biol       Date:  2018-06-18       Impact factor: 15.040

5.  Loss of Rab25 promotes the development of intestinal neoplasia in mice and is associated with human colorectal adenocarcinomas.

Authors:  Ki Taek Nam; Hyuk-Joon Lee; J Joshua Smith; Lynne A Lapierre; Vidya P Kamath; Xi Chen; Bruce J Aronow; Timothy J Yeatman; Sheela G Bhartur; Benjamin C Calhoun; Brian Condie; Nancy R Manley; R Daniel Beauchamp; Robert J Coffey; James R Goldenring
Journal:  J Clin Invest       Date:  2010-02-08       Impact factor: 14.808

Review 6.  Endosomal microdomains: Formation and function.

Authors:  Anne Norris; Barth D Grant
Journal:  Curr Opin Cell Biol       Date:  2020-04-01       Impact factor: 8.382

7.  Expression of Rab25 correlates with the invasion and metastasis of gastric cancer.

Authors:  Chuanwu Cao; Chenhui Lu; Jichong Xu; Jiaxing Zhang; Jun Zhang; Maoquan Li
Journal:  Chin J Cancer Res       Date:  2013-04       Impact factor: 5.087

8.  A phosphoinositide conversion mechanism for exit from endosomes.

Authors:  Katharina Ketel; Michael Krauss; Anne-Sophie Nicot; Dmytro Puchkov; Marnix Wieffer; Rainer Müller; Devaraj Subramanian; Carsten Schultz; Jocelyn Laporte; Volker Haucke
Journal:  Nature       Date:  2016-01-13       Impact factor: 49.962

9.  Array CGH profiling of favourable histology Wilms tumours reveals novel gains and losses associated with relapse.

Authors:  R Natrajan; R D Williams; S N Hing; A Mackay; J S Reis-Filho; K Fenwick; M Iravani; H Valgeirsson; A Grigoriadis; C F Langford; O Dovey; S G Gregory; B L Weber; A Ashworth; P E Grundy; K Pritchard-Jones; C Jones
Journal:  J Pathol       Date:  2006-09       Impact factor: 7.996

10.  Statin use and breast cancer survival - a Swedish nationwide study.

Authors:  Signe Borgquist; Per Broberg; Jasaman Tojjar; Håkan Olsson
Journal:  BMC Cancer       Date:  2019-01-11       Impact factor: 4.430
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  7 in total

1.  Persistent cell migration emerges from a coupling between protrusion dynamics and polarized trafficking.

Authors:  Kotryna Vaidžiulytė; Anne-Sophie Macé; Aude Battistella; William Beng; Kristine Schauer; Mathieu Coppey
Journal:  Elife       Date:  2022-03-18       Impact factor: 8.713

Review 2.  Dance of The Golgi: Understanding Golgi Dynamics in Cancer Metastasis.

Authors:  Rakhee Bajaj; Amanda N Warner; Jared F Fradette; Don L Gibbons
Journal:  Cells       Date:  2022-04-28       Impact factor: 7.666

3.  Mitochondrial respiration restricts Listeria monocytogenes infection by slowing down host cell receptor recycling.

Authors:  Anna Spier; Michael G Connor; Thomas Steiner; Filipe Carvalho; Pascale Cossart; Wolfgang Eisenreich; Timothy Wai; Fabrizia Stavru
Journal:  Cell Rep       Date:  2021-11-09       Impact factor: 9.423

Review 4.  Deliver on Time or Pay the Fine: Scheduling in Membrane Trafficking.

Authors:  Giampaolo Placidi; Carlo C Campa
Journal:  Int J Mol Sci       Date:  2021-10-29       Impact factor: 5.923

5.  Alteration in Rab11-mediated endocytic trafficking of LDL receptor contributes to angiotensin II-induced cholesterol accumulation and injury in podocytes.

Authors:  Jijia Hu; Zijing Zhu; Zhaowei Chen; Qian Yang; Wei Liang; Guohua Ding
Journal:  Cell Prolif       Date:  2022-05-14       Impact factor: 8.755

Review 6.  Rab GTPases: The principal players in crafting the regulatory landscape of endosomal trafficking.

Authors:  Jing Zhang; Zongyan Jiang; Anbing Shi
Journal:  Comput Struct Biotechnol J       Date:  2022-08-11       Impact factor: 6.155

Review 7.  Linking Late Endosomal Cholesterol with Cancer Progression and Anticancer Drug Resistance.

Authors:  Mai K L Nguyen; Jaimy Jose; Mohamed Wahba; Marc Bernaus-Esqué; Andrew J Hoy; Carlos Enrich; Carles Rentero; Thomas Grewal
Journal:  Int J Mol Sci       Date:  2022-06-29       Impact factor: 6.208
  7 in total

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