Literature DB >> 33404849

Mouse NTCP-Mediated Rosuvastatin Uptake In Vitro and in Slc10a1-Deficient Mice.

Laura E Russell1, Marianne K DeGorter1, Richard H Ho2, Brenda F Leake2, Crystal L Schmerk3, Sara E Mansell3, Richard B Kim4,5.   

Abstract

Entities:  

Keywords:  bile acid transporters; drug transporters; hepatic uptake transport; knockout mice; solute carrier (SLC) transporters

Year:  2021        PMID： 33404849     DOI： 10.1208/s12248-020-00540-2

Source DB:  PubMed          Journal:  AAPS J        ISSN： 1550-7416            Impact factor:   4.009


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  22 in total

1.  Disposition of atorvastatin, rosuvastatin, and simvastatin in oatp1b2-/- mice and intraindividual variability in human subjects.

Authors:  M K DeGorter; B L Urquhart; U Gradhand; R G Tirona; R B Kim
Journal:  J Clin Pharmacol       Date:  2011-12-13       Impact factor: 3.126

Review 2.  Statins: mechanism of action and effects.

Authors:  C Stancu; A Sima
Journal:  J Cell Mol Med       Date:  2001 Oct-Dec       Impact factor: 5.310

3.  Organic anion transporting polypeptide 1a/1b-knockout mice provide insights into hepatic handling of bilirubin, bile acids, and drugs.

Authors:  Evita van de Steeg; Els Wagenaar; Cornelia M M van der Kruijssen; Johanna E C Burggraaff; Dirk R de Waart; Ronald P J Oude Elferink; Kathryn E Kenworthy; Alfred H Schinkel
Journal:  J Clin Invest       Date:  2010-07-19       Impact factor: 14.808

4.  Quantitative assessment of the contribution of sodium-dependent taurocholate co-transporting polypeptide (NTCP) to the hepatic uptake of rosuvastatin, pitavastatin and fluvastatin.

Authors:  Yi-an Bi; Xi Qiu; Charles J Rotter; Emi Kimoto; Mary Piotrowski; Manthena V Varma; Ayman F Ei-Kattan; Yurong Lai
Journal:  Biopharm Drug Dispos       Date:  2013-10-03       Impact factor: 1.627

5.  Preclinical and clinical pharmacology of Rosuvastatin, a new 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor.

Authors:  F McTaggart; L Buckett; R Davidson; G Holdgate; A McCormick; D Schneck; G Smith; M Warwick
Journal:  Am J Cardiol       Date:  2001-03-08       Impact factor: 2.778

6.  Drug and bile acid transporters in rosuvastatin hepatic uptake: function, expression, and pharmacogenetics.

Authors:  Richard H Ho; Rommel G Tirona; Brenda F Leake; Hartmut Glaeser; Wooin Lee; Christopher J Lemke; Yi Wang; Richard B Kim
Journal:  Gastroenterology       Date:  2006-03-06       Impact factor: 22.682

7.  Clinical and pharmacogenetic predictors of circulating atorvastatin and rosuvastatin concentrations in routine clinical care.

Authors:  Marianne K DeGorter; Rommel G Tirona; Ute I Schwarz; Yun-Hee Choi; George K Dresser; Neville Suskin; Kathryn Myers; GuangYong Zou; Otito Iwuchukwu; Wei-Qi Wei; Russell A Wilke; Robert A Hegele; Richard B Kim
Journal:  Circ Cardiovasc Genet       Date:  2013-07-22

8.  Targeted disruption of murine organic anion-transporting polypeptide 1b2 (Oatp1b2/Slco1b2) significantly alters disposition of prototypical drug substrates pravastatin and rifampin.

Authors:  Hani Zaher; Henriette E Meyer zu Schwabedissen; Rommel G Tirona; Melissa L Cox; Leslie A Obert; Nidhi Agrawal; Joe Palandra; Jeffrey L Stock; Richard B Kim; Joseph A Ware
Journal:  Mol Pharmacol       Date:  2008-04-15       Impact factor: 4.436

9.  SLCO1B1 variants and statin-induced myopathy--a genomewide study.

Authors:  E Link; S Parish; J Armitage; L Bowman; S Heath; F Matsuda; I Gut; M Lathrop; R Collins
Journal:  N Engl J Med       Date:  2008-07-23       Impact factor: 91.245

10.  Utility of a novel Oatp1b2 knockout mouse model for evaluating the role of Oatp1b2 in the hepatic uptake of model compounds.

Authors:  Cuiping Chen; Jeffery L Stock; Xingrong Liu; Jilin Shi; Jeffrey W Van Deusen; Debra A DiMattia; Robert G Dullea; Sonia M de Morais
Journal:  Drug Metab Dispos       Date:  2008-06-12       Impact factor: 3.922
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