| Literature DB >> 3340394 |
Abstract
Force feeding the Egyptian toads (Bufo regularis) with gibberellin A3 (10 ppm) twice a week for 5 months induced neoplasms in 8 out of 50 (16%) experimental animals. Primary tumours developed in the liver (hepatocellular carcinomas). Two secondary tumours in the kidneys and another 2 in the ovaries of toads developed due to metastases from the hepatocellular carcinomas. The results show that gibberellic acid (gibberellin A3) has a carcinogenic effect in the Egyptian toads.Entities:
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Year: 1988 PMID: 3340394 DOI: 10.1159/000226532
Source DB: PubMed Journal: Oncology ISSN: 0030-2414 Impact factor: 2.935