Literature DB >> 33403171

Decidualized Stroma in Pelvic Lymph Nodes in a Pregnant Patient With Cervical Squamous Cell Carcinoma: A Case Report.

Anoshia Afzal1, Phillip Mingola1, Michael Quinton1, Roy Zhang1.   

Abstract

Decidualized endometrial stroma is an uncommon finding in lymph nodes but is typically found in the setting of endometriosis where endometrial glands give a hint toward the diagnosis. On the other hand, endometrial stroma with no identifiable endometrial glands can be challenging to differentiate from metastatic squamous cell carcinoma. We report a case of a 22-year-old female who presented to our medical center as a known case of cervical squamous cell carcinoma. The patient desired future fertility and became pregnant. She was treated during her second trimester and underwent a radical cesarean hysterectomy at 37 weeks' gestation with bilateral pelvic lymph node dissection. Resection showed residual moderately differentiated squamous cell carcinoma of the cervix with lymphovascular invasion. Two pelvic lymph nodes were found to have decidualized stroma. Immunohistochemistry was done to rule out metastasis and no metastatic carcinoma was identified in any of the lymph nodes. It is necessary to be aware of the possibility of decidualized stromal changes in pelvic lymph nodes to avoid misdiagnosis.
Copyright © 2020, Afzal et al.

Entities:  

Keywords:  decidualized; immunohistochemistry; pelvic lymph nodes; stroma

Year:  2020        PMID: 33403171      PMCID: PMC7773312          DOI: 10.7759/cureus.11741

Source DB:  PubMed          Journal:  Cureus        ISSN: 2168-8184


  8 in total

Review 1.  [Ectopic decidua: variability of presentation in pregnancy and differential diagnoses].

Authors:  G Canlorbe; I Goubin-Versini; E Azria; R Abdul-Razak; J-M Muray
Journal:  Gynecol Obstet Fertil       Date:  2012-03-30

Review 2.  Ectopic decidua mimicking metastatic lesions--report of three cases and review of the literature.

Authors:  A Kondi-Pafiti; D Grapsa; K Kontogianni-Katsarou; K Papadias; E Kairi-Vassilatou
Journal:  Eur J Gynaecol Oncol       Date:  2005       Impact factor: 0.196

3.  Ectopic decidual reaction mimicking peritoneal tubercles: a report of three cases.

Authors:  Shailaja Shukla; Mukta Pujani; Sanjeet Kumar Singh
Journal:  Indian J Pathol Microbiol       Date:  2008 Oct-Dec       Impact factor: 0.740

4.  Pregnancy-associated ectopic decidua.

Authors:  P Zaytsev; J B Taxy
Journal:  Am J Surg Pathol       Date:  1987-07       Impact factor: 6.394

5.  Ectopic decidual cell reaction in para-aortic and pelvic lymph nodes in the presence of cervical squamous cell carcinoma during pregnancy.

Authors:  M Ashraf; C B Boyd; W A Beresford
Journal:  J Surg Oncol       Date:  1984-05       Impact factor: 3.454

6.  Ectopic decidual reaction of the uterine cervix: frequency and cytologic presentation.

Authors:  V Schneider; L A Barnes
Journal:  Acta Cytol       Date:  1981 Nov-Dec       Impact factor: 2.319

7.  Ectopic decidua of pelvic lymph nodes: a potential diagnostic pitfall.

Authors:  Debbie C Wu; Sharon Hirschowitz; Sathima Natarajan
Journal:  Arch Pathol Lab Med       Date:  2005-05       Impact factor: 5.534

8.  Ectopic decidua and metastatic squamous carcinoma: presentation in a single pelvic lymph node.

Authors:  C J Cobb
Journal:  J Surg Oncol       Date:  1988-06       Impact factor: 3.454

  8 in total

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