Literature DB >> 33403087

Iliac Telangiectatic Osteosarcoma - A Rare Presentation and Diagnostic Pitfall: A Case Report.

Y C Khaw1, J K Wong1, Y Sahran1, M Z Nor-Azman1, W I Faisham1.   

Abstract

Telangiectatic osteosarcoma is a rare variant of osteosarcoma and can be easily misdiagnosed as aneurysmal bone cyst. We report an atypical case of iliac telangiectatic osteosarcoma in a young healthy female, who presents with painful slow growing expansile lytic septate lesion in the left hemipelvis, which is initially treated as aneurysmal bone cyst. The diagnosis of aneurysmal bone cyst is made after histopathological examination of core needle biopsy. Her condition became unstable and massive bleeding is noted at the lesion site after sclerosant injection. She undergoes emergency hemipelvectomy and eventually the biopsy turns up to be telangiectatic osteosarcoma. Our case highlights that core needle biopsy is not useful in making diagnosis for iliac telangiectatic carcinoma. Hence, an open biopsy should be carried out in our case. This case also emphasises on careful evaluation for malignancy which is mandatory because bleeding from pelvis after an unsuitable treatment can be grave, to the extent that major amputation hemipelvectomy is an option. Even though telangiectatic osteosarcoma has the same prognosis and treatment with conventional osteosarcoma, the outcome of delayed treatment for telangiectatic osteosarcoma is not good due to the dilemma in establishing an early correct diagnosis.
© 2020 Malaysian Orthopaedic Association (MOA). All Rights Reserved.

Entities:  

Keywords:  biopsy; histopathology; iliac; osteosarcoma; telangiectatic

Year:  2020        PMID: 33403087      PMCID: PMC7751993          DOI: 10.5704/MOJ.2011.034

Source DB:  PubMed          Journal:  Malays Orthop J        ISSN: 1985-2533


  5 in total

1.  [Accuracy of different preoperative biopsy techniques in diagnosis of osteosarcomas and their value in prognostic evaluation].

Authors:  Junqing Yuan; Huizhen Zhang; Zhiming Jiang; Jun Zhou; Qingcheng Yang; Zhichang Zhang
Journal:  Zhonghua Bing Li Xue Za Zhi       Date:  2015-05

Review 2.  Telangiectatic osteosarcoma.

Authors:  Nikhil A Sangle; Lester J Layfield
Journal:  Arch Pathol Lab Med       Date:  2012-05       Impact factor: 5.534

3.  Telangiectatic osteosarcoma: a review of 87 cases.

Authors:  Andrea Angelini; Andreas F Mavrogenis; Giulia Trovarelli; Stefano Ferrari; Piero Picci; Pietro Ruggieri
Journal:  J Cancer Res Clin Oncol       Date:  2016-07-28       Impact factor: 4.553

4.  Telangiectatic osteosarcoma: a review of literature.

Authors:  Jun-Jian Liu; Shen Liu; Jian-Guang Wang; Wei Zhu; Ying-Qi Hua; Wei Sun; Zheng-Dong Cai
Journal:  Onco Targets Ther       Date:  2013-05-28       Impact factor: 4.147

5.  Hemipelvectomy- only a salvage therapy?

Authors:  Christian Wedemeyer; Max Daniel Kauther
Journal:  Orthop Rev (Pavia)       Date:  2011-03-17
  5 in total

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